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February 2021

All Providers

Blue Cross and BCN provide $0 cost sharing for COVID‑19 vaccine coverage

Blue Cross Blue Shield of Michigan and Blue Care Network are waiving all copays, deductibles and coinsurance for the administration of COVID-19 vaccines to all commercial members during the government’s multi-phased approach to vaccine distribution. Medicare is covering the vaccine costs for Medicare members.

To assist you, we’ve created a new document to support provider offices preparing for COVID-19 vaccines. The COVID-19 vaccine information for providers document includes guidelines on distribution, coverage, billing, reporting and more, using the most current information available.

We also encourage health care providers to review their list of patients to determine which ones are now eligible to receive the vaccine, and to consider reaching out to assist them in their efforts to obtain a vaccine.

You can find the COVID-19 vaccine information for providers document on the Coronavirus information updates for providers link on the on the BCBSM Newsletters and Resources and BCN Provider Publications and Resources pages of web-DENIS under COVID-19 vaccine information. It’s also on our public website at bcbsm.com/coronavirus.

For more information about our decision to provide COVID-19 vaccine coverage at 0% cost sharing, read the Blue Cross news release.


Addressing implicit bias in health care can improve care delivery

You might have heard that implicit bias plays a role in how health care is delivered in doctor’s offices, hospitals and other health care settings. But what exactly is meant by implicit bias?

Implicit bias refers to the attitudes, stereotypes and generalizations that affect our understanding, actions and decisions in an unconscious manner. It often results in  prejudices in favor of — or against — a thing, person or group.

“All human beings are wired to have bias, and biases are often based on assumptions and stereotypes that are learned over time,” explained Bridget Hurd, vice president of Inclusion and Diversity for Blue Cross Blue Shield of Michigan. “These unrealized or unconscious beliefs can affect our decision-making.”

In a health care setting, implicit bias can have dangerous consequences.

“Every medical professional is mission-driven to heal their patient, but research indicates that bias shows in various ways in the delivery of health care — more often implicitly rather than explicitly,” said President and CEO Daniel J. Loepp in a recent blog “It benefits all medical professionals to spend time working to recognize where implicit bias may be present in the delivery of care and developing approaches to address it to the benefit of patients everywhere.”

Consider these examples:

  • Non-white patients presenting to the emergency room with the same symptoms as white Americans are less likely to receive pain medication, according to an article in Physician’s Weekly.
  • An article published in the National Academy of Sciences reported that a survey of white medical students in 2016 showed that many had false beliefs about the biological differences between Blacks and whites, leading to different treatment recommendations.
  • Early in the COVID-19 pandemic, reports indicated that African-Americans with concerning symptoms weren’t tested as often as their white counterparts, according to a review of billing information conducted by a biotech data firm.

Creating widespread understanding of these disparities in how health care delivery differs based on implicit bias is the first step in successfully addressing this issue.

That’s why Blue Cross is rolling out implicit bias education to health care providers over the next two years. It covers such topics as the science of bias, how it influences behaviors and patient outcomes, and how to make efforts to overcome implicit bias.

In September, leaders and staff at 40 physician organizations that participate in the Physician Group Incentive Program were introduced to implicit bias education. Next, it’s being rolled out to patient-centered medical home physicians and office staff.

“Creating awareness among physicians and office staff is an important step in building cultural competency and addressing gaps in care that may occur due to biases related to race, ethnicity, gender, sexual orientation, obesity or socioeconomic status,” said Hurd, who is leading the new Office of Health and Health Care Disparities.

Practices with PCMH designation will be required to take part in implicit bias educational opportunities this year to continue to receive value-based reimbursement tied to the PCMH designation.

Additionally, Gov. Gretchen Whitmer announced a directive last year that requires medical professionals to go through implicit bias training when obtaining or renewing their licenses.


Get ready for Availity: Technical requirements

Online provider toolsThis is part of a series of articles on Availity®, the new provider portal that will become available later this year

As we’ve communicated previously, Blue Cross Blue Shield of Michigan and Blue Care Network will move to the Availity provider portal later in 2021. We want your organization to have the best experience possible when using Availity. For a smooth transition, you should have the following:

  • A high-speed internet connection
  • Google Chrome as your browser (Chrome is the preferred browser, but Microsoft Edge, version 79 or higher, and Firefox® are also supported. Internet Explorer®, version 11.0 or higher, is supported but not recommended.)
  • The ability to enable pop-up windows, allow JavaScript and allow images to load automatically
  • 1024 x 768 pixels or greater screen resolution
  • Up-to-date antivirus software
  • The latest version of Adobe® Reader, to view PDF documents

Tip: The latest Availity technical requirements are available on the Availity website.** Scroll down and click on the Requirements tab.

Questions?

If you have questions about the move to Availity, check our Frequently Asked Questions document first. If your question isn’t already answered there, submit your question to ProviderPortalQuestions@bcbsm.com so we can consider adding it to the FAQ document. If you need immediate assistance or have a question specific to a certain member or situation, use our website resources or contact Provider Inquiry.

Web resources:

  • Log in as a provider at bcbsm.com.
  • Find prior authorization information for Michigan providers at ereferrals.bcbsm.com.
  • Find prior authorization information for non-Michigan providers and medical policy information by going to bcbsm.com/providers and clicking on Quick Links.

Provider Inquiry numbers are available at bcbsm.com/providers:

  • Click on Contact Us.
  • Click on the type of provider you are.
  • Click on Provider Inquiry.

Call the Blue Cross Web Support Help Desk at 1-877-258-3932 if you have problems with the current Blue Cross Provider Secured Services site.

**Blue Cross Blue Shield of Michigan doesn’t own or control this website.

Previous articles about Availity
In case you missed them, here are the articles about Availity we’ve already published:


2021 CPT and HCPCS Update now available

We recently created a new document, the 2021 CPT and HCPCS Update, to let you know about new and deleted CPT and HCPCS codes. It’s been posted on web-DENIS on the Clinical Criteria & Resources page.

As you may have read in the January Record, the Centers for Medicare & Medicaid Services had delayed the release of its 2021 HCPCS codes so we were only able to share a CPT Update document at that time.

This new document also includes updated information about the coverage decisions for certain CPT codes, so you’ll want to use it as your reference for new CPT and HCPCS codes for 2021. As future updates occur throughout the year, we’ll let you know via Record articles.

To access the 2021 CPT and HCPCS Update from web-DENIS, follow these steps:

  1. Click on BCBSM Provider Publications and Resources.
  2. Click on Newsletters and Resources.
  3. Click on Clinical Criteria & Resources (or look under What’s New).
  4. Scroll down to HCPCS and CPT Updates.

Blue Cross adds Billing/Claims page

At the end of 2020, we added a Billing/Claims page to the BCBSM Newsletters & Resources section of our secure website. It organizes useful billing and claims information and links on one convenient page for Blue Cross Blue Shield of Michigan commercial and Medicare Plus Blue℠. You’ll find:

  • Provider manuals for Blue Cross commercial and Medicare Plus Blue
  • User guides and job aids
  • Commonly used forms
  • Additional resources

Take a moment to discover all the information included on the new Blue Cross Billing/Claims page. Here’s how to find it:

  1. Log in as a provider at bcbsm.com.
  2. Click on BCBSM Provider Publications and Resources.
  3. Click on Newsletters & Resources.
  4. Under Popular Links, click on Billing/Claims.

Billing chart: Blues highlight medical, benefit policy changes

You’ll find the latest information about procedure codes and Blue Cross Blue Shield of Michigan billing guidelines in the following chart.

This billing chart is organized numerically by procedure code. Newly approved procedures will appear under the New Payable Procedures heading. Procedures for which we have changed a billing guideline or added a new payable group will appear under Updates to Payable Procedures. Procedures for which we are clarifying our guidelines will appear under Policy Clarifications. New procedures that are not covered will appear under Experimental Procedures.

You will also see that descriptions for the codes are no longer included. This is a result of recent negotiations with the AMA on use of the codes.

We will publish information about new BCBS groups or changes to group benefits under the Group Benefit Changes heading.

For more detailed descriptions of the BCBSM policies for these procedures, please check under the Medical/Payment Policy tab in Explainer on web-DENIS. To access this online information:

  • Log in to web-DENIS.
  • Click on BCBSM Provider Publications & Resources.
  • Click on Benefit Policy for a Code.
  • Click on Topic.
  • Under Topic Criteria, click on the drop-down arrow next to Choose Identifier Type and then click on HCPCS Code.
  • Enter the procedure code.
  • Click on Finish.
  • Click on Search.
Code* BCBSM changes to:
Basic Benefit and Medical Policy, Group
Variations Payment Policy, Guidelines
UPDATES TO PAYABLE PROCEDURES

J9047

Basic benefit and medical policy
 
Kyprolis (carfilzomib)

Kyprolis (carfilzomib), procedure code J9047, is payable for U.S. Food and Drug Administration-approved clarified indications. Effective Aug. 1, 2020, These indications have been updated to include treatment of adult patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy in combination with lenalidomide and dexamethasone; or dexamethasone; or daratumumab and dexamethasone.

J9228

Basic benefit and medical policy
 
Yervoy (ipilimumab)

Yervoy (ipilimumab), procedure code J9228, is payable for the updated FDA-approved indications.

Indications have been updated to include treatment of patients with hepatocellular carcinoma who have been previously treated with sorafenib, in combination with nivolumab. Also, Yervoy has been approved for treatment of adult patients with metastatic non-small cell lung cancer expressing PD-L1 (≥1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations, as first-line treatment in combination with nivolumab. In addition to treatment of adult patients with metastatic or recurrent non-small cell lung cancer with no EGFR or ALK genomic tumor aberrations as first-line treatment, in combination with nivolumab and two cycles of platinum doublet chemotherapy.

J9999

Basic benefit and medical policy

Monjuvi (tafasitamab-cxix)

Monjuvi (tafasitamab-cxix) is payable when billed for FDA-approved indications, effective July 31, 2020. Monjuvi (tafasitamab-cxix) should be reported with procedure code J9999 and the appropriate national drug code until a permanent code is established.

URMBT groups are excluded from coverage of this drug.

Monjuvi (tafasitamab-cxix) is a CD19-directed cytolytic antibody indicated in combination with lenalidomide for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma, or DLBCL, not otherwise specified, including DLBCL arising from low-grade lymphomawho aren’t eligible for autologous stem cell transplant.

Dosage and administration:

Administer premedications prior to starting Monjuvi
The recommended dosage of Monjuvi is 12 mg/kg as an intravenous infusion according to the following dosing schedule:

  • Cycle 1: Days 1, 4, 8, 15 and 22 of the 28-day cycle.
  • Cycles 2 and 3: Days 1, 8, 15 and 22 of each 28-day cycle.
  • Cycle 4 and beyond: Days 1 and 15 of each 28-day cycle.

Administer Monjuvi in combination with lenalidomide for a maximum of 12 cycles and then continue Monjuvi as monotherapy until disease progression or unacceptable toxicity.

Dosage forms and strengths:

For injection: 200 mg of tafasitamab-cxix as lyophilized powder in single dose vial for reconstitution. Instillation volume based on volumetric measurements using pyelography, not to exceed 15 mL (60 mg of mitomycin).

Condition code 89

Basic benefit and medical policy

Condition code 89 approved

The National Uniform Billing Committee approved new condition code 89. This is effective Jan. 1, 2021.

POLICY CLARIFICATIONS

33215, 33216, 33217, 33218, 33220, 33223, 33230, 33231, 33240, 33241, 33243, 33244, 33249, 33262, 33263, 33264, 33270, 33271, 33272, 33273, 93260, 93261, 93282, 93283, 93284, 93287, 93289, 93295, 93296 

Not covered:

0571T, 0572T, 0573T, 0574T, 0575T, 0576T, 0577T, 0578T, 0614T

Basic benefit and medical policy

Implantable Cardioverter Defibrillator (ICD), Including Subcutaneous ICDs, policy

The safety and effectiveness of an automatic implantable cardioverter defibrillator, or ICD, and electronic surveillance of the AICD have been established. It may be considered a useful therapeutic option for patients who meet selection criteria.

The safety and effectiveness of a subcutaneous automatic implantable cardioverter defibrillator and electronic surveillance of the AICD have been established. It may be considered a useful therapeutic option for patients who meet selection criteria.

Inclusionary criteria for the indication of cardiac sarcoid have been added, effective Jan. 1, 2021.

Inclusions:

Standard automatic implantable cardioverter defibrillators

I. Adults

The use of the automatic implantable cardioverter defibrillator may be considered established in adults who meet the following criteria:

Primary prevention

Inclusions (one of the following):

  • Ischemic cardiomyopathy with New York Heart Association, or NYHA, functional Class II or Class III symptoms, a history of myocardial infarction at least 40 days before ICD treatment and left ventricular ejection fraction of 35% or less
  • Ischemic cardiomyopathy with NYHA functional Class I symptoms, a history of myocardial infarction at least 40 days before ICD treatment and left ventricular ejection fraction of 30% or less
  • Nonischemic dilated cardiomyopathy and left ventricular ejection fraction of 35% or less, after reversible causes have been excluded, and the response to optimal medical therapy has been adequately determined
  • Hypertrophic cardiomyopathy, or HCM, with one or more major risk factors for sudden cardiac death (history of premature HCM-related sudden death in one or more first-degree relatives younger than 50 years; left ventricular hypertrophy greater than 30 mm; one or more runs of nonsustained ventricular tachycardia at heart rates of 120 beats per minute or greater on 24-hour Holter monitoring; prior unexplained syncope inconsistent with neurocardiogenic origin) and judged to be at high risk for sudden cardiac death by a physician experienced in the care of patients with HCM.
  • Diagnosis of any one of the following cardiac ion channelopathies and considered to be at high risk for sudden cardiac death:
    • Congenital long QT syndrome
    • Brugada syndrome
    • Short QT syndrome
    • Catecholaminergic polymorphic ventricular tachycardia
  • Diagnosis of cardiac sarcoid and considered to be at high risk for sudden cardiac death:
    • Spontaneous sustained ventricular arrhythmias, including prior cardiac arrest, if meaningful survival of greater than one year is expected;
    • LVEF 35% or less, despite optimal medical therapy and a period of immunosuppression (if there is active inflammation), if meaningful survival of greater than one year is expected;
    • LVEF greater than 35%, if meaningful survival of greater than one year is expected; and one of the following:
      • Syncope or near-syncope, believed to be arrhythmic in etiology
      • Evidence of myocardial scar by cardiac MRI or positron emission tomographic scan
      • Inducible sustained ventricular arrhythmias (>30 seconds of monomorphic VT orpolymorphic VT) or clinically relevant VF
    • An indication for permanent pacemaker implantation

Secondary prevention

Inclusions:

  • Patients with a history of a life-threatening clinical event associated with ventricular arrhythmic events, such as sustained ventricular tachyarrhythmia after reversible causes (e.g., acute ischemia) have been excluded.

II. Pediatrics

Inclusions:

The use of the ICD or SCD may be considered established in children who meet any of the following criteria:

  • Survivors of cardiac arrest, after reversible causes have been excluded.
  • Symptomatic, sustained ventricular tachycardia in association with congenital heart disease in patients who have undergone hemodynamic and electrophysiologic evaluation
  • Congenital heart disease with recurrent syncope of undetermined origin in the presence of either ventricular dysfunction or inducible ventricular arrhythmias
  • Hypertrophic cardiomyopathy, or HCM, with one or more major risk factors for sudden cardiac death (history or premature HCM-related sudden death in one or more first-degree relatives younger than 50 years; massive left ventricular hypertrophy based on age-specific norms; prior unexplained syncope inconsistent with neurocardiogenic origin) and judged to be at high risk for sudden cardiac death by a physician experienced in the care of patients with HCM
  • Diagnosis of any one of the following cardiac ion channelopathies and considered to be at high risk for sudden cardiac death:
    • Congenital long QT syndrome
    • Brugada syndrome
    • Short QT syndrome
    • Catecholaminergic polymorphic ventricular tachycardia

Subcutaneous automatic implantable cardioverter defibrillators

FDA-approved subcutaneous cardioverter-defibrillators are established for adults who meet patient selection criteria for an implanted cardioverter defibrillator and who don’t need pacing and the placement of a conventional AICD is precluded due to any of the following conditions. These also apply to pediatric patients in addition to those inclusions in the pediatric section:

  • Poor vascular access secondary to dialysis or other vascular conditions
  • A high risk for infection, e.g., immunocompromised patients or those with a history of a previous transvenous infection
  • History of congenital heart disease with anatomic limitations for transvenous placement of the AICD
  • History of need for explantation of a transvenous ICD due to a complication, with ongoing need for ICD therapy

Exclusions:

The use of the ICD is considered experimental in primary prevention patients who:

  • Have had an acute myocardial infarction (e.g., less than 40 days before ICD treatment);
  • Have New York Heart Association class IV congestive heart failure (unless patient is eligible to receive a combination cardiac resynchronization therapy ICD device)
  • Have had a cardiac revascularization procedure in past three months (coronary artery bypass graft or percutaneous transluminal coronary angioplasty) or are candidates for a cardiac revascularization procedure
  • Have noncardiac disease that would be associated with life expectancy less than one year

The use of the ICD in secondary prevention is considered experimental for all other indications than those listed above.

The use of the ICD in pediatric patients is considered experimental for all other indications than those listed above.

33361, 33362, 33363, 33364, 33365, 33366, 33367, 33368, 33369

Not covered:
33999**

**Not Otherwise Classified code used to report non-FDA-approved systems

Basic benefit and medical policy

Transcatheter aortic valve replacement

Transcatheter aortic valve replacement performed with an FDA-approved transcatheter heart valve system, when performed using an approach consistent with the device’s FDA-approved labeling may be indicated for patients with aortic stenosis.

Exclusionary criteria have been updated, effective Jan. 1, 2021.

Inclusions:

Transcatheter aortic valve replacement with a device approved by the FDA and performed using an approach consistent with the device’s FDA-approved labeling is established for patients with aortic stenosis when all of the following conditions are present:

  • Severe aortic stenosis with a calcified aortic annulus or failure (stenosed, insufficient or combined) of a surgical bioprosthetic aortic valve
  • New York Heart Association heart failure, Class II, III or IV symptoms
  • Left ventricular ejection fraction greater than 20%
  • One of the following:
    • Patient isn’t an operable candidate for open surgery, as judged by at least two cardiovascular specialists including a cardiac surgeon.
    • Patient is an operable candidate but is at high risk** for open surgery.
    • Patient is at intermediate or greater surgical risk for open aortic valve replacement (only when used in concordance with FDA regulations for Sapiens XT Transcatheter Heart Valve, see below)
    • Patient is at low surgical risk** for open aortic valve replacement (only when used in concordance with FDA regulations for Sapien 3, Sapien 3 Ultra, CoreValve Evolut R or CoreValve Evolut PRO)

Edwards SAPIEN XT Transcatheter Heart Valve:

  1. Severe aortic stenosis with a calcified aortic annulus and one or more of the following:
    • An aortic valve area of ≤ 1.0 cm² or aortic valve area index ≤ 0.6 cm2/m2
    • A mean aortic valve gradient ≥ 40 mmHg
    • A peak aortic-jet velocity ≥ 4.0 m/sec
    • Native anatomy appropriate for the 23, 26, or 29 mm valve system (between 18 and 28 mm)
  1. New York Heart Association heart failure Class II, III or IV symptoms
  2. Patient isn’t a candidate for open surgery, as judged by a heart team, including a cardiac surgeon or to be at high or greater risk** for open surgical therapy.
  3. Patient is at intermediate surgical risk** for open aortic valve replacement.

Edwards SAPIEN and Edwards SAPIEN 3 Ultra
Patient with severe aortic valve stenosis who is at low risk** for death or major complications associated with open heart surgery.

LOTUS Edge™ Valve System

  1. Aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis
    • An aortic valve area of ≤ 1.0 cm2 OR aortic valve area index ≤ 0.6 cm2/m2)
  1. Patient isn’t a candidate for open surgery, as judged by a heart team, including a cardiac surgeon, or is at high or greater risk** for open surgical therapy.

Medtronic CoreValve™ (Evolut) System

  1. Severe aortic stenosis with a calcified aortic annulus and one or more of the following:
    • An aortic valve area of ≤ 1.0 cm² or aortic valve area index ≤ 0.6 cm2/m2
    • A mean aortic valve gradient ≥ 40 mmHg
    • A peak aortic-jet velocity ≥ 4.0 m/sec
    • Native aortic annulus diameters between 23 and 31 mm
  1. New York Heart Association heart failure Class II, III or IV symptoms
  2. Patient with severe aortic valve stenosis who is at low risk or higher** for death or major complications associated with open-heart surgery.

**Definition of predictive risk factor based on the Society of Thoracic Surgeons, known as STS, predicted risk score for major complications and other clinical comorbidities unmeasured by the STS risk calculator for open surgery.

  • Low risk – predicted operative risk score of less than 3% or 4%
  • Intermediate risk – predicted operative risk score of 3% to 7%
  • High risk – predicted operative risk score of 8% or higher; or judged by a heart team, which includes an experienced cardiac surgeon and a cardiologist, to have an expected mortality risk of ≥ 15% within 30 days

Exclusions:

Transcatheter aortic valve replacement is considered experimental for all other indications including, but not limited to:

  • The individual is an appropriate candidate for the standard, open surgical approach but has refused
  • Hypersensitivity or contraindication to an anticoagulation/antiplatelet regimen
  • Presence of active bacterial endocarditis or other active infections
  • Presence of unicuspid or bicuspid aortic valve
  • Non-FDA-approved systems or approaches including:
    • Portico, and JenaValve systems
    • Transcaval approach

Relative contraindications:

In some cases, the benefits of transcatheter aortic valve implantation may exceed potential risks. In such instances, the cardiologist should provide an attestation indicating that relative contraindications exist and that the patient fully understands all risks. While the items below aren’t absolute exclusions, the safety and effectiveness of transcatheter aortic valve implantation haven’t been evaluated in patients with the following characteristics or co-morbidities:

  • Patients without aortic stenosis
  • Untreated, clinically significant coronary artery disease requiring revascularization
  • Cardiogenic shock manifested by low cardiac output, vasopressor dependence, or mechanical hemodynamic support
  • Trans arterial access not able to accommodate an 18-Fr sheath
  • Sinus of valsalva anatomy that would prevent adequate coronary perfusion
  • End-stage renal disease requiring chronic dialysis or creatinine clearance <20 cc/min
  • Symptomatic carotid or vertebral artery disease
  • Safety, effectiveness and durability haven’t been established for valve-in-valve procedures
  • Non-calcified aortic annulus
  • Severe ventricular dysfunction with ejection fraction < 20%
  • Congenital unicuspid or congenital bicuspid aortic valve
  • Mixed aortic valve disease (aortic stenosis and aortic regurgitation with predominant aortic regurgitation > 3+)
  • Prosthetic ring in any position
  • Severe mitral annular calcification, severe mitral insufficiency, moderate to severe mitral or tricuspid regurgitation, or Gorlin syndrome
  • Moderate to severe mitral stenosis
  • Blood dyscrasias defined as: leukopenia, acute anemia (Hb < 9 g/dL), thrombocytopenia, history of bleeding diathesis or coagulopathy, or hypercoagulable states
  • Hypertrophic cardiomyopathy with or without obstruction
  • Echocardiographic evidence of intracardiac mass, thrombus, or vegetation
  • Excessive calcification of vessel at access site
  • Bulky calcified aortic valve leaflets in close proximity to coronary ostia
  • The safety and effectiveness of the Medtronic CoreValve™ system haven’t been evaluated in the pediatric population.

81210, 81445

Basic benefit and medical policy

Genetic testing  ̶  BRAF mutation in selecting melanoma patients for targeted therapy

The medical policy statement has been updated for the Genetic Testing  ̶  BRAF Mutation in Selecting Melanoma Patients for Targeted Therapy policy. The policy effective date is Jan. 1, 2021.

Medical policy statement

Testing for BRAF V600 variants in tumor tissue of patients with unresectable or metastatic melanoma is established to select patients for treatment with FDA-approved BRAF or MEK inhibitors.

Testing for BRAF V600 variants in tumor tissue of patients with resected stage III melanoma is established to select patients for treatment with FDA-approved BRAF or MEK inhibitors.

Testing for BRAF V600 variants for all other patients with melanoma is considered experimental.

Testing for genetic mutations using a panel with 5-50 genes may also be considered appropriate for cutaneous melanoma (Stage 3 and Stage 4).

Testing for BRAF V600 or the above panel with 5-50 genes for all other reasons is experimental.

Inclusions and exclusions:

Refer to the pharmacy policies (Vemurafenib, Trametinib, Cobimetinib) for patient selection.

81420, 81507, 81599,** 81479***

Not covered:
81422, 0060U, 0168U

Payment policy

**Not Otherwise Classified code used to report test of multianalyte assays with algorithmic analysis

***NOC code used if others don’t apply and the test doesn’t involve an algorithmic analysis

Basic benefit and medical policy

Noninvasive prenatal screening

The safety and effectiveness of noninvasive prenatal screening for fetal aneuploidies using cell-free fetal DNA have been established. It may be considered a useful diagnostic option when indicated.

The peer-reviewed medical literature hasn’t demonstrated the clinical utility of noninvasive prenatal screening for microdeletions using cell-free fetal DNA. Therefore, this service is considered experimental.

Exclusions regarding twin zygosity and Vanadis® have been added, effective Jan. 1, 2021.

Inclusions:

  • Nucleic acid sequencing-based testing of maternal plasma to screen for trisomy 21 in women with singleton pregnancies. (Karyotyping would be necessary to exclude the possibility of a false positive nucleic acid sequencing-based test.)
  • Concurrent nucleic acid sequencing-based testing of maternal plasma for trisomy 13 or 18 in women who are eligible for and are undergoing nucleic acid sequencing-based testing of maternal plasma for trisomy 21.

Exclusions:

  • Nucleic acid sequencing-based testing of maternal plasma for trisomy 21 in women with twin or multiple gestation pregnancies
  • Nucleic acid sequencing-based testing of maternal plasma for trisomy 13 or 18, other than in the situations specified above
  • Nucleic acid sequencing-based testing of maternal plasma for fetal sex chromosome aneuploidies
  • Nucleic acid sequencing-based testing of maternal plasma for microdeletions
  • Nucleic acid sequencing-based testing of maternal plasma for twin zygosity
  • Vanadis® NIPT of maternal plasma to screen for trisomy 21, 18 and 13

Policy guidelines:

Karyotyping would be necessary to exclude the possibility of a false-positive, nucleic acid sequencing-based test. Before testing, women should be counseled about the risk of a false-positive test. In Committee Opinion No. 640, the American College of Obstetricians and Gynecologists (2015) recommended that all patients receive information on the risks and benefits of various methods of prenatal screening and diagnostic testing for fetal aneuploidies, including the option of no testing.

Studies published to date on noninvasive prenatal screening for fetal aneuploidies have reported rare but occasional false positives. False-positive findings have been found to be associated with factors including placental mosaicism, vanishing twins and maternal malignancies. Diagnostic testing is necessary to confirm positive cell-free fetal DNA tests, and management decisions should not be based solely on the results of cell-free fetal DNA testing. The American College of Obstetricians and Gynecologists further recommended that patients with indeterminate or uninterpretable (i.e., “no call”) cell-free fetal DNA test results be referred for genetic counseling and offered ultrasound evaluation and diagnostic testing because “no call” findings have been associated with an increased risk of aneuploidy.

Cell-free DNA screening doesn’t assess risk of neural tube defects. Patients should continue to be offered ultrasound or maternal serum alpha-fetoprotein screening.

Genetic counseling

Experts recommend formal genetic counseling for patients who are at risk for inherited disorders and who wish to undergo genetic testing. Interpreting the results of genetic tests and understanding risk factors can be difficult for some patients; genetic counseling helps individuals understand the impact of genetic testing, including the possible effects the test results could have on the individual or their family members. It should be noted that genetic counseling may alter the utilization of genetic testing substantially and may reduce inappropriate testing; further genetic counseling should be performed by an individual with experience and expertise in genetic medicine and genetic testing methods.

81479, 81599, 84999

Basic benefit and medical policy

Gene expression profiling for cutaneous melanoma

The medical policy statement has been updated for the Gene Expression Profiling for Cutaneous Melanoma policy.

Medical policy statement

The peer-reviewed medical literature hasn’t demonstrated the clinical utility of gene expression profiling for the diagnosis or prognosis of cutaneous melanoma. Therefore, this service is considered experimental.

Inclusions and exclusions:

Excluded tests include but are not limited to:

  • Pigmented Lesion Assay
  • myPath Melanoma
  • DecisionDx-Melanoma

The policy effective date is Jan. 1, 2021.

Established

86294, 86386, 88120, 88121

Experimental

0012M, 0013M, 81599

Basic benefit and medical policy

Urinary biomarkers for bladder cancer

The safety and effectiveness of FDA-approved urinary tumor marker tests for bladder cancer have been established.

An FDA-approved urinary tumor marker test may be considered a useful diagnostic option when used as an adjunct to cytology and cystoscopy. The policy effective date is Jan. 1, 2021.

Inclusions:

The assessment of FDA-approved urinary tumor markers for bladder cancer, as an adjunct to cytology and cystoscopy, is considered established in:

  • The diagnosis of urinary bladder malignancy in members at very high risk.
  • The follow-up of members with a history of urinary bladder malignancy when the measurements of these markers is deemed essential in making management decisions.

Exclusions:

  • All other indications for bladder cancer not specified under the inclusions

The peer-reviewed medical literature hasn’t demonstrated the analytical validity and clinical utility outcomes of Cxbladde™ therefore, Cxbladder tests are considered experimental.

Established

94772, 94774, 94775, 94776, 94777, A4556, A4557, E0619

Experimental

E0618

Basic benefit and medical policy

Home cardiorespiratory monitoring  ̶  pediatric

The criteria have been updated for the Home Cardiorespiratory Monitoring  ̶  Pediatric policy, effective Jan. 1, 2021.

Inclusions:

Home cardiorespiratory monitoring when initiated in infants younger than 12 months of age in any of the following situations:

  • Those who have experienced a brief resolved unexplained event (previously known as apparent life-threatening event) and aren’t considered lower risk following clinical evaluation
  • Those with tracheostomies or anatomic abnormalities that make them vulnerable to airway compromise.
  • Those with neurologic or metabolic disorders affecting respiratory control, including central apnea and apnea of prematurity
  • Those with chronic lung disease (e.g.., bronchopulmonary dysplasia)

Home cardiorespiratory monitoring in children over 12 months of age in any of the following situations:

  • Those with home noninvasive ventilator use
  • Those with home invasive ventilator use
  • Those with chronic lung disease
  • Those with cyanotic heart disease

Exclusions:

  • Home cardiorespiratory monitoring when used as a strategy to reduce the risk of sudden infant death syndrome
  • Home cardiorespiratory monitoring in all other conditions including, but not limited to, the diagnosis of obstructive sleep apnea
  • Apnea monitors without an event recorder

J0585

Basic benefit and medical policy

Botox (onabotulinumtoxinA)

Effective July 8, 2020, Botox (onabotulinumtoxinA) is payable for the following updated FDA-approved indications:

  • Treatment of spasticity in patients ages 2 years and older.

  Dosage and administration:

  • Adult upper limb spasticity: Select dose based on muscles affected, severity of muscle activity, prior response to treatment and adverse event history. Electromyographic guidance recommended
  • Adult lower limb spasticity: Recommended total dose 300 units to 400 units divided across ankle and toe muscles
  • Pediatric upper limb spasticity: Recommended total dose 3 units/kg to 6 units/kg (maximum 200 units) divided among affected muscles

Pediatric lower limb spasticity: Recommended total dose of 4 units/kg to 8 units/kg (maximum 300 units) divided among affected muscles

J0587

Basic benefit and medical policy

Myobloc (rimabotulinumtoxinB)

Effective Aug. 20, 2019, Myobloc (rimabotulinumtoxinB) is payable for the following updated FDA-approved indications:

  • Treatment of chronic sialorrhea in adults

Dosage and administration:

Chronic sialorrhea: Recommended dosage is 1,500 units to 3,500 units; 500 units to 1,500 units per parotid gland and 250 units per submandibular gland; no more frequent than every 12 weeks

J0588

Basic benefit and medical policy

Xeomin (incobotulinumtoxinA)

Effective Aug. 18, 2020, Xeomin (incobotulinumtoxinA) is payable for the following updated FDA-approved indications:

  • Upper limb spasticity in pediatric patients 2 to 17 years of age, excluding spasticity caused by cerebral palsy

 Dosage and administration:

Upper limb spasticity in pediatric patients, excluding spasticity caused by cerebral palsy: the recommended total dose is 8 units/kg (maximum 200 units) per single upper limb or 16 units/kg (maximum 400 units) in both upper limbs, divided among affected muscles

J3490
J3590

Basic benefit and medical policy

Spravato (esketamine)

Effective July 31, 2020, Spravato (esketamine) is covered for the following FDA-approved indications:

  • Depressive symptoms in adults with major depressive disorder with acute suicidal ideation or behavior

Limitations of use:

  • The effectiveness of Spravato in preventing suicide or in reducing suicidal ideation or behavior hasn’t been demonstrated. Use of Spravato doesn’t preclude the need for hospitalization if clinically warranted, even if patients experience improvement after an initial dose of Spravato.
This drug isn’t a benefit for URMBT.

J3490
J3590

Basic benefit and medical policy

Veklury (remdesivir)

Effective Oct. 22, 2020, Veklury (remdesivir) is covered for the following FDA-approved indications:

Veklury is a SARS-CoV-2 nucleotide analog RNA polymerase inhibitor indicated for adults and pediatric patients (ages 12 and older and weighing at least 40 kg) for the treatment of coronavirus disease 2019 requiring hospitalization. Veklury should only be administered in a hospital or in a health care setting capable of providing acute care comparable to inpatient hospital care.

Dosage and administration:

  • Testing: In all patients, before initiating Veklury and during treatment as clinically appropriate, perform renal and hepatic laboratory testing and assess prothrombin time.
  • Recommended dosage in adults and pediatric patients ages 12 and older and weighing at least 40 kg: A single loading dose of Veklury 200 mg on Day 1 followed by once-daily maintenance doses of Veklury 100 mg from Day 2 infused over 30 to 120 minutes.
  • For patients not requiring invasive mechanical ventilation or ECMO, the recommended total treatment duration is five days. If a patient doesn’t demonstrate clinical improvement, treatment may be extended for up to five additional days for a total treatment duration of up to 10 days.
  • For patients requiring invasive mechanical ventilation or ECMO, the recommended total treatment duration is 10 days.
  • Administer Veklury via intravenous infusion over 30 to 120 minutes.
  • Renal impairment: Veklury isn’t recommended in patients with eGFR less than 30 mL/min. 
  • Dose preparation and administration: Refer to the full prescribing information for further details for both formulations.
  • Storage of prepared dosages: Veklury contains no preservative.

Dosage forms and strengths:

  • For injection: 100 mg of remdesivir as a lyophilized powder, in a single-dose vial.
  • Injection: 100 mg/20 mL (5 mg/mL) remdesivir, in a single-dose vial.

This drug isn’t a benefit for URMBT.

J7645

Payment policy

Procedure code J7645

Procedure code J7645 is payable to urgent care providers.

J9023

Basic benefit and medical policy

Bavencio (avelumab)

Effective June 30, 2020, Bavencio (avelumab) is approved for the following updated FDA-approved indication:

Maintenance treatment of patients with locally advanced or metastatic urothelial carcinoma that hasn’t progressed with first-line platinum-containing chemotherapy.

EXPERIMENTAL PROCEDURES

New codes added

0604T, 0605T, 0606T

Experimental

0378T, 0379T

Basic benefit and medical policy

Home monitoring device for age-related macular degeneration

Home monitoring devices using preferential hyperacuity perimetry, or PHP, and telemonitoring of results for age-related macular degeneration are considered experimental. There is insufficient evidence in the peer-reviewed medical literature to demonstrate that these devices improve clinical outcomes over standard monitoring approaches.

New procedure codes have been added to this policy.

The policy effective date is Jan. 1, 2021.

Established

52441, 52442, C9769

Experimental

0619T

Basic benefit and medical policy

Prostatic urethral lift procedure for the treatment of BPH

The safety and efficacy of the prostatic urethral lift procedure for the treatment of benign prostatic hypertrophy, or BPH, have been established. 

It’s a useful therapeutic option for men with symptomatic BPH who have failed conventional pharmacologic therapy. 

New procedure codes C9769 and 0619T have been added to this policy. The policy effective date is Jan. 1, 2021.

Inclusions:

Candidates for the prostatic urethral lift procedure must meet all the following guidelines:

  • Age 45 years or older
  • A documented diagnosis of symptomatic benign prostatic hypertrophy of the lateral lobes of the prostate including, but not limited to, the following symptoms:
    • Difficulty starting and stopping urination (hesitancy and straining)
    • Decreased strength of the urine stream (weak flow)
    • Dribbling after urination
    • Feeling that the bladder isn’t completely empty
    • An urge to urinate again soon after urinating (urgency)
    • Pain during urination (dysuria)
    • Nocturia – waking up several times during the night with the urge to urinate
    • Frequent urinary tract infections secondary to urinary obstruction
  • Documented failure of, inability to tolerate or undesirable side effects of pharmacologic intervention for BPH including, but not limited to:
    • Alpha blockers, such as Uroxatral, Cardura, Rapaflo, Flomax or Hytrin
    • 5-alpha reductase inhibitors for BPH, such as Avodart or Proscar
    • Combination drugs using both an alpha blocker and a 5-alpha reductase inhibitor

Exclusions:

Patients not meeting the patient selection criteria above.

Professional

HEDIS medical record reviews begin in February

Each year from February through May, Blue Cross Blue Shield of Michigan conducts Healthcare Effectiveness Data and Information Set, or HEDIS®, medical record reviews for members who live in Michigan. This year, Blue Cross’ HEDIS clinical consultants will conduct HEDIS reviews for members with Blue Cross PPO plans (including commercial, Medicare Plus Blue℠ and individual products) who had services in 2020.

As part of their efforts to support HEDIS and government-required programs, the Blue Cross and Blue Shield Association mandates who can retrieve medical records for patients living in Michigan but enrolled in another state’s Blue plan. Blue Cross is authorized to retrieve medical records for patients enrolled in a Blue Medicare Advantage PPO plan in another state.

Inovalon, an independent data and analytics firm, is authorized to retrieve medical records for patients enrolled in all Blue Cross commercial plans, as well as Blue Medicare Private Fee-for-Service and HMO plans.

For the HEDIS reviews, Blue Cross looks for details that may not have been captured in claims data, such as blood pressure readings, HbA1c lab results and colorectal screenings. This information helps us improve health care quality for our members.

Blue Cross’ HEDIS clinical consultants will contact you to schedule an appointment for a HEDIS review or request that you fax the necessary records. The HEDIS review also requires proof of service documentation for data collected from a medical record.

If you have questions or concerns, contact Laurie Latvis at llatvis@bcbsm.com.

HEDIS® is a registered trademark of the National Committee for Quality Assurance


CAHPS research offers insights into improving the patient experience

Research from the Consumer Assessment of Healthcare Providers and Systems, or CAHPS®, survey can help providers better understand their Medicare patients’ needs and expectations. The Centers for Medicare & Medicaid Services annually compiles findings about improving the patient experience and understanding health outcomes through this survey.

You can access reports, articles and case studies through the Research on Improving the Patient Experience page** of the Agency for Healthcare Research and Quality website.

Check out the CAHPS survey tip sheet to learn more about why this annual survey is important, how it’s conducted, what questions are asked and ways you can successfully address care opportunities for patients.

**Blue Cross Blue Shield of Michigan doesn’t own or control this website.


Date change: CareCentrix to manage Medicare Advantage home health care prior authorizations starting June 1

As reported in the December 2020 issue of The Record and in the January-February 2021 issue of BCN Provider News, Blue Cross Blue Shield of Michigan and Blue Care Network have contracted with CareCentrix® to manage prior authorizations for home health care services for Medicare Plus Blue℠ and BCN Advantage℠ members.

We’re delaying the date on which this program will begin. CareCentrix will manage home health service authorizations for episodes of care starting on or after June 1, 2021.

For episodes of care that start before June 1, 2021, you don’t need to submit prior authorization requests for home health care services.


Telehealth visits, including annual wellness visits, available to Medicare Advantage patients

We encourage health care professionals to remind their Medicare Advantage patients that they can use telehealth services for appointments with their health care providers.

Remember that for all telehealth visits, the documentation in the office note must include the following information:

  • Type of telehealth contact (for example, visual, audio, email or portal)
  • Type of video service (for example, Skype, Zoom or BlueJeans)
  • Location of patient and provider
  • Patient-informed consent documented (in other words, he or she understands and accepts the privacy and security risks of telehealth medicine)

The following may also be documented for telehealth, telephone, e-visits and virtual check-ins:

  • Patient self-reported blood pressure readings from any digital device
  • Advanced illness and frailty exclusions

Keep in mind that Medicare Advantage patients can complete their free annual wellness visit in one of the following ways:

  • A traditional face-to-face visit in your office
  • An online telehealth visit using a smartphone, computer or tablet with audio and video capability
  • A telephone-only visit for patients who don’t have video capability

The procedure codes are:

  • G0402: Welcome to Medicare visit
  • G0438: Annual wellness visit, initial
  • G0439: Annual wellness visit, subsequent

For more information, view the Controlling Blood Pressure tip sheet and the Advanced Illness and Frailty Exclusions Guide.


Changes coming to preferred products for drugs covered under the medical benefit for most members

For dates of service on or after April 1, 2021, we’re designating certain medications as preferred products. This change will affect most Blue Cross Blue Shield of Michigan commercial and all Medicare Plus Blue℠, Blue Care Network commercial and BCN Advantage℠ members.

Here’s what you need to know when prescribing these products:

  • Preferred products vary based on members’ health care plans.
  • For members who start treatment on or after April 1, prescribe preferred products when possible. (See the “Submitting requests for prior authorization” section of this article for details.)
  • For members who receive nonpreferred products for bevacizumab, trastuzumab and rituximab for courses of treatment that start before April 1, they can continue using the nonpreferred product until their authorizations expire. (We’ll contact our commercial members who receive these nonpreferred products and encourage them to discuss treatment options with you.)

Note: For commercial members, the requirements outlined in this article:

  • Apply only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs covered under the medical benefit
  • Do not apply to UAW Retiree Medical Benefits Trust non-Medicare members or to members covered by the Blue Cross and Blue Shield Federal Employee Program® or MESSA.

Preferred and nonpreferred products

We’re designating the following products as preferred and nonpreferred for Blue Cross commercial fully insured groups, Blue Cross commercial members with individual coverage, Medicare Plus Blue members, BCN commercial members and BCN Advantage members:

Bevacizumab (reference product: Avastin®)

  • Preferred products:
    • Mvasi™ (bevacizumab-awwb), HCPCS code Q5107
    • Zirabev® (bevacizumab-bvzr), HCPCS code Q5118
  • Nonpreferred product: Avastin (bevacizumab), HCPCS code J9035

Rituximab (reference product: Rituxan®)

  • Preferred products:
    • Ruxience™ (rituximab-pvvr), HCPCS code Q5119
    • Riabni™ (rituximab-arrx), HCPCS code J3590 (will become a unique code)
  • Nonpreferred products:
    • Rituxan (rituximab), HCPCS code J9312
    • Truxima® (rituximab-abbs), HCPCS code Q5115

Trastuzumab (reference product: Herceptin®)

  • Preferred products:
    • Kanjinti™ (trastuzumab-anns), HCPCS code Q5117
    • Trazimera™ (trastuzumab-qyyp), HCPCS code Q5116
  • Nonpreferred products:
    • Herceptin (trastuzumab), HCPCS code J9355
    • Herzuma® (trastuzumab-pkrb), HCPCS code Q5113
    • Ogivri® (trastuzumab-dkst), HCPCS code Q5114
    • Ontruzant® (trastuzumab-dttb), HCPCS code Q5112

Additional preferred and nonpreferred products for most commercial members

We’re designating the following products as preferred and nonpreferred for Blue Cross commercial fully insured groups, Blue Cross commercial members with individual coverage and BCN commercial members.

Pegfilgrastim (reference product: Neulasta®)

  • Preferred products:
    • Neulasta/Neulasta Onpro® (pegfilgrastim), HCPCS code J2505
    • Nyvepria™ (pegfilgrastim-apgf), HCPCS code J3590
  • Nonpreferred products
    • Fulphila® (pegfilgrastim-jmdb), HCPCS code Q5108
    • Udenyca® (pegfilgrastim-cbqv), HCPCS code Q5111
    • Ziextenzo™ (pegfilgrastim-bmez), HCPCS code Q5120

Additional preferred and nonpreferred products for Medicare Advantage members

We’re designating the following products as preferred and nonpreferred for Medicare Plus Blue members and BCN Advantage members: 

Pegfilgrastim (reference product: Neulasta)

  • Preferred products:
    • Neulasta/Neulasta Onpro® (pegfilgrastim), HCPCS code J2505
    • Udenyca® (pegfilgrastim-cbqv), HCPCS code Q5111
  • Nonpreferred products:
    • Fulphila® (pegfilgrastim-jmdb), HCPCS code Q5108
    • Ziextenzo™ (pegfilgrastim-bmez), HCPCS code Q5120
    • Nyvepria™ (pegfilgrastim-apgf), HCPCS code J3590

Submitting requests for prior authorization

Here’s how to submit prior authorization requests for preferred products and nonpreferred products.

  • For select preferred products: These products require prior authorization through AIM Specialty Health®. Submit the request through the AIM provider portal** or by calling the AIM Contact Center at 1-844-377-1278. For information about registering for and accessing the AIM ProviderPortal, see the Frequently Asked Questions page** on the AIM website.
  • For nonpreferred products — for members who must take nonpreferred products: These products have authorization requirements. Submit the prior authorization request through the NovoLogix online tool. NovoLogix offers real-time status checks and immediate approvals for certain medications. If you have access to Provider Secured Services, you can enter authorization requests through NovoLogix. If you need to request access to Provider Secured Services, complete the Provider Secured Access Application form and fax it to the number on the form.

Authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.

Lists of requirements

See the following lists to view requirements for these products.

For commercial members:

For Medicare Advantage members, see the Medical Drug and Step Therapy Prior Authorization List for Medicare Plus Blue PPO and BCN Advantage members.

We’ll update the requirements lists with the new information before April 1.

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


For nonpreferred filgrastim products, submit prior authorization requests using NovoLogix® starting in April

For courses of treatment that start on or after April 1, 2021, you’ll need to submit prior authorization requests for all members for nonpreferred filgrastim products using the NovoLogix® online tool.

As we’ve communicated previously, for courses of treatment that started Oct. 1, 2020, through March 31, 2021, you should submit requests to AIM Specialty Health® for Blue Care Network commercial, Medicare Plus Blue℠ and BCN Advantage℠ members. And for Blue Cross Blue Shield of Michigan fully insured commercial members, for courses of treatment that started on or after Oct. 1, 2020, you’re already submitting these requests using NovoLogix so nothing will change.

Note: For commercial members, these requirements:

  • Apply only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs covered under the medical benefit
  • Do not apply to members covered by the Blue Cross and Blue Shield Federal Employee Program®, the Michigan Education Special Services Association or UAW Retiree Medical Benefits Trust non-Medicare members

For details on the preferred and nonpreferred filgrastim products, refer to the August 2020 Record article.

As a reminder, authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.


Some drugs won’t be payable when administered by a health care provider to Blue Cross and BCN commercial members

For dates of service on or after April 1, 2021, the medications listed below won’t be payable by Blue Cross Blue Shield of Michigan and Blue Care Network when administered by a physician or other health care professional.

This change affects Blue Cross commercial and Blue Care Network commercial members. The reason for the change is that these drugs can safely and conveniently be self-administered by the member in the member’s home. They don’t require administration by a health care professional.

The following drugs are currently payable under either the medical benefit or the pharmacy benefit. Starting April 1, they’re payable only under the pharmacy benefit.

  • Actimmune® (interferon gamma-1b), HCPCS code J9216
  • Akynzeo® (netupitant / palonosetron), HCPCS code J8655
  • Arcalyst® (rilonacept), HCPCS code J2793
  • Banophen™ / Ormir™ / Pharbedryl™ (diphenhydramine), HCPCS code Q0163
  • Emend® (aprepitant), HCPCS code J8501
  • Imitrex® (sumatriptan succinate), HCPCS code J3030
  • Granisetron HCl® (granisetron hydrochloride), HCPCS code Q0166 / S0091
  • Marinol® / Syndros® (dronabinol), HCPCS code Q0167
  • Megestrol acetate®, HCPCS code S0179
  • Pegasys® (peginterferon alfa-2a), HCPCS code S0145
  • Pegintron® (peginterferon alfa-2b), HCPCS code S0148
  • Promethazine HCl® (phenadoz), HCPCS code Q0169
  • Regranex® (becaplermin), HCPCS code S0157
  • Sensipar® (cinacalcet), HCPCS code J0604
  • Varubi® (rolapitant), HCPCS code J8670
  • Zofran® / Zuplenz® (ondansetron), HCPCS code Q0162 / S0119

There are no other changes that apply to the management of these therapies at this time.

For more information

To view requirements for drugs covered under the pharmacy benefit, see the Blue Cross and BCN Prior authorization and step therapy coverage criteria document. This document is available from the following pages on the ereferrals.bcbsm.com website:

For a list of requirements related to drugs covered under the medical benefit, see the Blue Cross and BCN utilization management medical drug list for Blue Cross PPO (commercial) and BCN HMO (commercial) members document.

We’ll update the requirements lists with the new information prior to April 1, 2021.


Quarterly update: Requirements changed for some commercial medical benefit drugs

Blue Cross Blue Shield of Michigan and Blue Care Network encourage proper utilization of high-cost medications that are covered under the medical benefit. As part of this effort, we maintain a comprehensive list of requirements for both Blue Cross and BCN commercial members.

During the fourth quarter of 2020, there were changes to prior authorization requirements, site-of-care requirements or both for Blue Cross commercial members for the following medical benefit drugs:

HCPCS code Brand name Generic name
J0596

Ruconest®

c-1 inhibitor recombinant
J0597

Berinert®

c-1 esterase
J0598

Cinryze®

c-1 esterase
J1290

Kalbitor®

ecallantide
J1442

Neupogen®

filgrastim
J1447

Granix®

tbo-filgrastim
J1444

Firazyr®

icatibant
J1444

Icatibant

icatibant hcl

For a detailed list of requirements, see the Blue Cross and BCN utilization management medical drug list.

This list is available on the Blue Cross Medical Benefit Drugs page at ereferrals.bcbsm.com.

These authorization requirements apply only to groups that currently participate in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. To view the list of Blue Cross commercial groups that don’t participate in the program, see the Specialty Pharmacy Prior Authorization Master Opt-in/out Group List.

As a reminder, an authorization approval isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.


Blue Cross offers additional mileage reimbursement for ground ambulance providers in 2021

During the first quarter of 2021, Blue Cross Blue Shield of Michigan and Blue Care Network are offering ground ambulance providers an opportunity to become eligible for additional reimbursement for mileage.

Ground ambulance providers who participate under the BCBSM and BCN Ambulance Provider Participation Agreement will be eligible for additional reimbursement associated with HCPCS code A0425. Reimbursement will depend on the number of providers who sign the agreement. This additional reimbursement is in addition to the 2.25% overall ambulance fee schedule increase for 2021.

The program will be reassessed every 12 months.

To receive this additional reimbursement, follow these steps:

  • Sign the joint BCBSM and BCN Ambulance Provider Participation Agreement if you haven’t already done so.
    • The signing period runs from Jan. 1 to March 31, 2021, for initial qualification.
  • Receive an additional percentage reimbursement for mileage.
    • The percentage will depend on the number of providers who sign the joint agreement (see table below).
    • The appropriate additional reimbursement percentage will be applied to code A0425 beginning on April 1, 2021.
Provider participation Additional percentage for mileage
If providers currently participate under the joint ambulance contract or sign it between Jan. 1 and March 31, 2021

5%

If all participating Blue Cross commercial providers participate under the combined agreement (allowing Blue Cross to retire the individual provider agreement) 15%
If the percentage of providers who sign the joint contract equals 90%, thereby expanding the number of participating providers.

20%


Reminder: AIM to handle prior authorization for some high-tech radiology services for Michigan FEP members

As we reported in the January issue of The Record, starting Feb. 1, 2021, AIM Specialty Health® will handle select high-tech radiology services for Michigan Blue Cross and Blue Shield Federal Employee Program® members receiving services in Michigan. AIM is an independent company that manages authorizations of select services for Blue Cross Blue Shield of Michigan.

Information about the AIM high-tech radiology prior authorization program for FEP members can be found on the ereferrals.bcbsm.com website.

To find the codes that require prior authorization through AIM for Michigan FEP members:

  • Go to ereferrals.bcbsm.com.
  • Click on Blue Cross on the blue bar.
  • Click on AIM-Managed Procedures.
  • Scroll down to Resources.
  • Click on Radiology services for Michigan Blue Cross and Blue Shield Federal Employee Program® members that requires authorization by AIM Specialty Health.

How to submit authorization requests

Submit authorization requests using one of the following methods:

As a reminder, requests should be submitted before the services are provided.

Note: Make sure to verify members have active coverage on the date of service and that services are covered under the FEP Blue Cross and Blue Shield Service Benefit Plan.

Additional information

Information about requesting authorization from AIM, including how to register for and use the AIM ProviderPortal,** can be found below.

Questions?

If you have questions, call AIM at 1-800-728-8008 or visit the AIM website.** You can also contact your provider consultant.

**Blue Cross Blue Shield of Michigan doesn’t own or control this website.


Helping patients with medication management

Medication adherence can be challenging for patients with a chronic illness, such as asthma, cardiovascular disease, diabetes or hypertension. Unfortunately, not all patients take their medication as prescribed and may be reluctant to discuss their reasons with their doctor.

A complete and accurate medication list maintained by patients is the foundation for addressing medication management issues, according to the Agency for Healthcare Research and Quality. Keeping a medication list may help identify behaviors that put some patients at risk for overdosing, underdosing or missing doses.

Following are several online resources to help patients keep track of their prescribed and over-the-counter medications:

Additional resources available to Blue Cross and Blue Shield Federal Employee Program® members include:

  • Personal Health Record, which stores members’ health care information to help them keep track of medical history, appointments, medications and more. Members can access the PHR in the MyBlue® member portal at fepblue.org or the MyBlue® app.
  • Nurse line at 1-888-258-3432, which can be used 24/7 if they have questions about health-related issues, including medications.
  • Telehealth services
    • Online or phone visits with a board-certified primary care doctor or specialist 24/7
    • Members can contact Teladoc® by phone at 1-855-636-1579, online at fepblue.org/telehealth or by using the FEP MyBlue® app
  • Coordinated Care program at 1-800-775-BLUE (2583) for support in coordinating care to manage health conditions, including medications, at home

If you or your patients have questions about FEP support services and benefits, call the Customer Service line at 1-800-482-3600.


Reminder: Register for upcoming training webinars

Provider Experience is continuing its series of training webinars for health care providers and staff. The webinars are designed to help you work more efficiently with Blue Cross Blue Shield of Michigan and Blue Care Network.

Here’s information on the upcoming training webinars:

Webinar name Date and time Registration
Blue Cross 201 — Claims Basics — Professional

Wednesday, Feb. 3, 2021
10 to 11 a.m.

Click here to register.
Blue Cross 201 — Claims Basics — Professional

Wednesday, Feb. 3, 2021
2 to 3 p.m.

Click here to register.
Autism Overview

Thursday, Feb. 4, 2021
10 to 11 a.m.

Click here to register.
Autism Overview

Thursday, Feb. 4, 2021
2 to 3 p.m.

Click here to register.
Autism Overview

Wednesday, Feb. 10, 2021
10 to 11 a.m.

Click here to register.
Autism Overview

Wednesday, Feb. 10, 2021
2 to 3 p.m.

Click here to register.
Blue Cross 201 — Claims Basics — Professional

Tuesday, March 2, 2021
10 to 11 a.m.

Click here to register.
Blue Cross 201 — Claims Basics — Professional

Tuesday, March 2, 2021
2 to 3 p.m.

Click here to register.

The Blue Cross 201 webinar series provides an in-depth learning opportunity and builds on information shared in our Blue Cross 101: Understanding the Basics webinar. This new webinar reviews the processes and tools available when submitting claims.

The Autism Overview webinar reviews current processes related to providing services to members with autism.

Recordings of previous webinars are available through web-DENIS on the Blue Cross Provider Publications and Resources and BCN Provider Publications and Resources pages as follows:

Blue Cross Provider Publications and Resources

  1. Log in to Provider Secured Services.
  2. Click on BCBSM Provider Publications and Resources.
  3. Click on BCBSM Newsletters and Resources.
  4. Click on Provider Training.
  5. In the Featured Links section of the page, check out 2020 Provider Training Webinars.

You can also get more information about online training, presentations and videos by clicking on the E-Learning icon at the top of the page.

BCN Provider Publications and Resources

  1. Log in to Provider Secured Services.
  2. Go to BCN Provider Publications and Resources.
  3. Under Other Resources, click on Learning Opportunities.
  4. Find the most recent webinars under 2020 Provider Training Webinars.

As additional training webinars become available, we’ll let you know via web-DENIS, The Record and BCN Provider News.

Facility

Date change: CareCentrix to manage Medicare Advantage home health care prior authorizations starting June 1

As reported in the December 2020 issue of The Record and in the January-February 2021 issue of BCN Provider News, Blue Cross Blue Shield of Michigan and Blue Care Network have contracted with CareCentrix® to manage prior authorizations for home health care services for Medicare Plus Blue℠ and BCN Advantage℠ members.

We’re delaying the date on which this program will begin. CareCentrix will manage home health service authorizations for episodes of care starting on or after June 1, 2021.

For episodes of care that start before June 1, 2021, you don’t need to submit prior authorization requests for home health care services.


Changes coming to preferred products for drugs covered under the medical benefit for most members

For dates of service on or after April 1, 2021, we’re designating certain medications as preferred products. This change will affect most Blue Cross Blue Shield of Michigan commercial and all Medicare Plus Blue℠, Blue Care Network commercial and BCN Advantage℠ members.

Here’s what you need to know when prescribing these products:

  • Preferred products vary based on members’ health care plans.
  • For members who start treatment on or after April 1, prescribe preferred products when possible. (See the “Submitting requests for prior authorization” section of this article for details.)
  • For members who receive nonpreferred products for bevacizumab, trastuzumab and rituximab for courses of treatment that start before April 1, they can continue using the nonpreferred product until their authorizations expire. (We’ll contact our commercial members who receive these nonpreferred products and encourage them to discuss treatment options with you.)

Note: For commercial members, the requirements outlined in this article:

  • Apply only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs covered under the medical benefit
  • Do not apply to UAW Retiree Medical Benefits Trust non-Medicare members or to members covered by the Blue Cross and Blue Shield Federal Employee Program® or MESSA.

Preferred and nonpreferred products

We’re designating the following products as preferred and nonpreferred for Blue Cross commercial fully insured groups, Blue Cross commercial members with individual coverage, Medicare Plus Blue members, BCN commercial members and BCN Advantage members:

Bevacizumab (reference product: Avastin®)

  • Preferred products:
    • Mvasi™ (bevacizumab-awwb), HCPCS code Q5107
    • Zirabev® (bevacizumab-bvzr), HCPCS code Q5118
  • Nonpreferred product: Avastin (bevacizumab), HCPCS code J9035

Rituximab (reference product: Rituxan®)

  • Preferred products:
    • Ruxience™ (rituximab-pvvr), HCPCS code Q5119
    • Riabni™ (rituximab-arrx), HCPCS code J3590 (will become a unique code)
  • Nonpreferred products:
    • Rituxan (rituximab), HCPCS code J9312
    • Truxima® (rituximab-abbs), HCPCS code Q5115

Trastuzumab (reference product: Herceptin®)

  • Preferred products:
    • Kanjinti™ (trastuzumab-anns), HCPCS code Q5117
    • Trazimera™ (trastuzumab-qyyp), HCPCS code Q5116
  • Nonpreferred products:
    • Herceptin (trastuzumab), HCPCS code J9355
    • Herzuma® (trastuzumab-pkrb), HCPCS code Q5113
    • Ogivri® (trastuzumab-dkst), HCPCS code Q5114
    • Ontruzant® (trastuzumab-dttb), HCPCS code Q5112

Additional preferred and nonpreferred products for most commercial members

We’re designating the following products as preferred and nonpreferred for Blue Cross commercial fully insured groups, Blue Cross commercial members with individual coverage and BCN commercial members.

Pegfilgrastim (reference product: Neulasta®)

  • Preferred products:
    • Neulasta/Neulasta Onpro® (pegfilgrastim), HCPCS code J2505
    • Nyvepria™ (pegfilgrastim-apgf), HCPCS code J3590
  • Nonpreferred products
    • Fulphila® (pegfilgrastim-jmdb), HCPCS code Q5108
    • Udenyca® (pegfilgrastim-cbqv), HCPCS code Q5111
    • Ziextenzo™ (pegfilgrastim-bmez), HCPCS code Q5120

Additional preferred and nonpreferred products for Medicare Advantage members

We’re designating the following products as preferred and nonpreferred for Medicare Plus Blue members and BCN Advantage members: 

Pegfilgrastim (reference product: Neulasta)

  • Preferred products:
    • Neulasta/Neulasta Onpro® (pegfilgrastim), HCPCS code J2505
    • Udenyca® (pegfilgrastim-cbqv), HCPCS code Q5111
  • Nonpreferred products:
    • Fulphila® (pegfilgrastim-jmdb), HCPCS code Q5108
    • Ziextenzo™ (pegfilgrastim-bmez), HCPCS code Q5120
    • Nyvepria™ (pegfilgrastim-apgf), HCPCS code J3590

Submitting requests for prior authorization

Here’s how to submit prior authorization requests for preferred products and nonpreferred products.

  • For select preferred products: These products require prior authorization through AIM Specialty Health®. Submit the request through the AIM provider portal** or by calling the AIM Contact Center at 1-844-377-1278. For information about registering for and accessing the AIM ProviderPortal, see the Frequently Asked Questions page** on the AIM website.
  • For nonpreferred products — for members who must take nonpreferred products: These products have authorization requirements. Submit the prior authorization request through the NovoLogix online tool. NovoLogix offers real-time status checks and immediate approvals for certain medications. If you have access to Provider Secured Services, you can enter authorization requests through NovoLogix. If you need to request access to Provider Secured Services, complete the Provider Secured Access Application form and fax it to the number on the form.

Authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.

Lists of requirements

See the following lists to view requirements for these products.

For commercial members:

For Medicare Advantage members, see the Medical Drug and Step Therapy Prior Authorization List for Medicare Plus Blue PPO and BCN Advantage members.

We’ll update the requirements lists with the new information before April 1.

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


For nonpreferred filgrastim products, submit prior authorization requests using NovoLogix® starting in April

For courses of treatment that start on or after April 1, 2021, you’ll need to submit prior authorization requests for all members for nonpreferred filgrastim products using the NovoLogix® online tool.

As we’ve communicated previously, for courses of treatment that started Oct. 1, 2020, through March 31, 2021, you should submit requests to AIM Specialty Health® for Blue Care Network commercial, Medicare Plus Blue℠ and BCN Advantage℠ members. And for Blue Cross Blue Shield of Michigan fully insured commercial members, for courses of treatment that started on or after Oct. 1, 2020, you’re already submitting these requests using NovoLogix so nothing will change.

Note: For commercial members, these requirements:

  • Apply only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs covered under the medical benefit
  • Do not apply to members covered by the Blue Cross and Blue Shield Federal Employee Program®, the Michigan Education Special Services Association or UAW Retiree Medical Benefits Trust non-Medicare members

For details on the preferred and nonpreferred filgrastim products, refer to the August 2020 Record article.

As a reminder, authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.


Some drugs won’t be payable when administered by a health care provider to Blue Cross and BCN commercial members

For dates of service on or after April 1, 2021, the medications listed below won’t be payable by Blue Cross Blue Shield of Michigan and Blue Care Network when administered by a physician or other health care professional.

This change affects Blue Cross commercial and Blue Care Network commercial members. The reason for the change is that these drugs can safely and conveniently be self-administered by the member in the member’s home. They don’t require administration by a health care professional.

The following drugs are currently payable under either the medical benefit or the pharmacy benefit. Starting April 1, they’re payable only under the pharmacy benefit.

  • Actimmune® (interferon gamma-1b), HCPCS code J9216
  • Akynzeo® (netupitant / palonosetron), HCPCS code J8655
  • Arcalyst® (rilonacept), HCPCS code J2793
  • Banophen™ / Ormir™ / Pharbedryl™ (diphenhydramine), HCPCS code Q0163
  • Emend® (aprepitant), HCPCS code J8501
  • Imitrex® (sumatriptan succinate), HCPCS code J3030
  • Granisetron HCl® (granisetron hydrochloride), HCPCS code Q0166 / S0091
  • Marinol® / Syndros® (dronabinol), HCPCS code Q0167
  • Megestrol acetate®, HCPCS code S0179
  • Pegasys® (peginterferon alfa-2a), HCPCS code S0145
  • Pegintron® (peginterferon alfa-2b), HCPCS code S0148
  • Promethazine HCl® (phenadoz), HCPCS code Q0169
  • Regranex® (becaplermin), HCPCS code S0157
  • Sensipar® (cinacalcet), HCPCS code J0604
  • Varubi® (rolapitant), HCPCS code J8670
  • Zofran® / Zuplenz® (ondansetron), HCPCS code Q0162 / S0119

There are no other changes that apply to the management of these therapies at this time.

For more information

To view requirements for drugs covered under the pharmacy benefit, see the Blue Cross and BCN Prior authorization and step therapy coverage criteria document. This document is available from the following pages on the ereferrals.bcbsm.com website:

For a list of requirements related to drugs covered under the medical benefit, see the Blue Cross and BCN utilization management medical drug list for Blue Cross PPO (commercial) and BCN HMO (commercial) members document.

We’ll update the requirements lists with the new information prior to April 1, 2021.


Quarterly update: Requirements changed for some commercial medical benefit drugs

Blue Cross Blue Shield of Michigan and Blue Care Network encourage proper utilization of high-cost medications that are covered under the medical benefit. As part of this effort, we maintain a comprehensive list of requirements for both Blue Cross and BCN commercial members.

During the fourth quarter of 2020, there were changes to prior authorization requirements, site-of-care requirements or both for Blue Cross commercial members for the following medical benefit drugs:

HCPCS code Brand name Generic name
J0596

Ruconest®

c-1 inhibitor recombinant
J0597

Berinert®

c-1 esterase
J0598

Cinryze®

c-1 esterase
J1290

Kalbitor®

ecallantide
J1442

Neupogen®

filgrastim
J1447

Granix®

tbo-filgrastim
J1444

Firazyr®

icatibant
J1444

Icatibant

icatibant hcl

For a detailed list of requirements, see the Blue Cross and BCN utilization management medical drug list.

This list is available on the Blue Cross Medical Benefit Drugs page at ereferrals.bcbsm.com.

These authorization requirements apply only to groups that currently participate in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. To view the list of Blue Cross commercial groups that don’t participate in the program, see the Specialty Pharmacy Prior Authorization Master Opt-in/out Group List.

As a reminder, an authorization approval isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.


Reminder: Register for upcoming training webinars

Provider Experience is continuing its series of training webinars for health care providers and staff. The webinars are designed to help you work more efficiently with Blue Cross Blue Shield of Michigan and Blue Care Network.

Here’s information on the upcoming training webinars:

Webinar name Date and time Registration
Blue Cross 201 — Claims Basics — Professional

Wednesday, Feb. 3, 2021
10 to 11 a.m.

Click here to register.
Blue Cross 201 — Claims Basics — Professional

Wednesday, Feb. 3, 2021
2 to 3 p.m.

Click here to register.
Autism Overview

Thursday, Feb. 4, 2021
10 to 11 a.m.

Click here to register.
Autism Overview

Thursday, Feb. 4, 2021
2 to 3 p.m.

Click here to register.
Autism Overview

Wednesday, Feb. 10, 2021
10 to 11 a.m.

Click here to register.
Autism Overview

Wednesday, Feb. 10, 2021
2 to 3 p.m.

Click here to register.
Blue Cross 201 — Claims Basics — Professional

Tuesday, March 2, 2021
10 to 11 a.m.

Click here to register.
Blue Cross 201 — Claims Basics — Professional

Tuesday, March 2, 2021
2 to 3 p.m.

Click here to register.

The Blue Cross 201 webinar series provides an in-depth learning opportunity and builds on information shared in our Blue Cross 101: Understanding the Basics webinar. This new webinar reviews the processes and tools available when submitting claims.

The Autism Overview webinar reviews current processes related to providing services to members with autism.

Recordings of previous webinars are available through web-DENIS on the Blue Cross Provider Publications and Resources and BCN Provider Publications and Resources pages as follows:

Blue Cross Provider Publications and Resources

  1. Log in to Provider Secured Services.
  2. Click on BCBSM Provider Publications and Resources.
  3. Click on BCBSM Newsletters and Resources.
  4. Click on Provider Training.
  5. In the Featured Links section of the page, check out 2020 Provider Training Webinars.

You can also get more information about online training, presentations and videos by clicking on the E-Learning icon at the top of the page.

BCN Provider Publications and Resources

  1. Log in to Provider Secured Services.
  2. Go to BCN Provider Publications and Resources.
  3. Under Other Resources, click on Learning Opportunities.
  4. Find the most recent webinars under 2020 Provider Training Webinars.

As additional training webinars become available, we’ll let you know via web-DENIS, The Record and BCN Provider News.

Pharmacy

Changes coming to preferred products for drugs covered under the medical benefit for most members

For dates of service on or after April 1, 2021, we’re designating certain medications as preferred products. This change will affect most Blue Cross Blue Shield of Michigan commercial and all Medicare Plus Blue℠, Blue Care Network commercial and BCN Advantage℠ members.

Here’s what you need to know when prescribing these products:

  • Preferred products vary based on members’ health care plans.
  • For members who start treatment on or after April 1, prescribe preferred products when possible. (See the “Submitting requests for prior authorization” section of this article for details.)
  • For members who receive nonpreferred products for bevacizumab, trastuzumab and rituximab for courses of treatment that start before April 1, they can continue using the nonpreferred product until their authorizations expire. (We’ll contact our commercial members who receive these nonpreferred products and encourage them to discuss treatment options with you.)

Note: For commercial members, the requirements outlined in this article:

  • Apply only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs covered under the medical benefit
  • Do not apply to UAW Retiree Medical Benefits Trust non-Medicare members or to members covered by the Blue Cross and Blue Shield Federal Employee Program® or MESSA.

Preferred and nonpreferred products

We’re designating the following products as preferred and nonpreferred for Blue Cross commercial fully insured groups, Blue Cross commercial members with individual coverage, Medicare Plus Blue members, BCN commercial members and BCN Advantage members:

Bevacizumab (reference product: Avastin®)

  • Preferred products:
    • Mvasi™ (bevacizumab-awwb), HCPCS code Q5107
    • Zirabev® (bevacizumab-bvzr), HCPCS code Q5118
  • Nonpreferred product: Avastin (bevacizumab), HCPCS code J9035

Rituximab (reference product: Rituxan®)

  • Preferred products:
    • Ruxience™ (rituximab-pvvr), HCPCS code Q5119
    • Riabni™ (rituximab-arrx), HCPCS code J3590 (will become a unique code)
  • Nonpreferred products:
    • Rituxan (rituximab), HCPCS code J9312
    • Truxima® (rituximab-abbs), HCPCS code Q5115

Trastuzumab (reference product: Herceptin®)

  • Preferred products:
    • Kanjinti™ (trastuzumab-anns), HCPCS code Q5117
    • Trazimera™ (trastuzumab-qyyp), HCPCS code Q5116
  • Nonpreferred products:
    • Herceptin (trastuzumab), HCPCS code J9355
    • Herzuma® (trastuzumab-pkrb), HCPCS code Q5113
    • Ogivri® (trastuzumab-dkst), HCPCS code Q5114
    • Ontruzant® (trastuzumab-dttb), HCPCS code Q5112

Additional preferred and nonpreferred products for most commercial members

We’re designating the following products as preferred and nonpreferred for Blue Cross commercial fully insured groups, Blue Cross commercial members with individual coverage and BCN commercial members.

Pegfilgrastim (reference product: Neulasta®)

  • Preferred products:
    • Neulasta/Neulasta Onpro® (pegfilgrastim), HCPCS code J2505
    • Nyvepria™ (pegfilgrastim-apgf), HCPCS code J3590
  • Nonpreferred products
    • Fulphila® (pegfilgrastim-jmdb), HCPCS code Q5108
    • Udenyca® (pegfilgrastim-cbqv), HCPCS code Q5111
    • Ziextenzo™ (pegfilgrastim-bmez), HCPCS code Q5120

Additional preferred and nonpreferred products for Medicare Advantage members

We’re designating the following products as preferred and nonpreferred for Medicare Plus Blue members and BCN Advantage members: 

Pegfilgrastim (reference product: Neulasta)

  • Preferred products:
    • Neulasta/Neulasta Onpro® (pegfilgrastim), HCPCS code J2505
    • Udenyca® (pegfilgrastim-cbqv), HCPCS code Q5111
  • Nonpreferred products:
    • Fulphila® (pegfilgrastim-jmdb), HCPCS code Q5108
    • Ziextenzo™ (pegfilgrastim-bmez), HCPCS code Q5120
    • Nyvepria™ (pegfilgrastim-apgf), HCPCS code J3590

Submitting requests for prior authorization

Here’s how to submit prior authorization requests for preferred products and nonpreferred products.

  • For select preferred products: These products require prior authorization through AIM Specialty Health®. Submit the request through the AIM provider portal** or by calling the AIM Contact Center at 1-844-377-1278. For information about registering for and accessing the AIM ProviderPortal, see the Frequently Asked Questions page** on the AIM website.
  • For nonpreferred products — for members who must take nonpreferred products: These products have authorization requirements. Submit the prior authorization request through the NovoLogix online tool. NovoLogix offers real-time status checks and immediate approvals for certain medications. If you have access to Provider Secured Services, you can enter authorization requests through NovoLogix. If you need to request access to Provider Secured Services, complete the Provider Secured Access Application form and fax it to the number on the form.

Authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.

Lists of requirements

See the following lists to view requirements for these products.

For commercial members:

For Medicare Advantage members, see the Medical Drug and Step Therapy Prior Authorization List for Medicare Plus Blue PPO and BCN Advantage members.

We’ll update the requirements lists with the new information before April 1.

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


For nonpreferred filgrastim products, submit prior authorization requests using NovoLogix® starting in April

For courses of treatment that start on or after April 1, 2021, you’ll need to submit prior authorization requests for all members for nonpreferred filgrastim products using the NovoLogix® online tool.

As we’ve communicated previously, for courses of treatment that started Oct. 1, 2020, through March 31, 2021, you should submit requests to AIM Specialty Health® for Blue Care Network commercial, Medicare Plus Blue℠ and BCN Advantage℠ members. And for Blue Cross Blue Shield of Michigan fully insured commercial members, for courses of treatment that started on or after Oct. 1, 2020, you’re already submitting these requests using NovoLogix so nothing will change.

Note: For commercial members, these requirements:

  • Apply only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs covered under the medical benefit
  • Do not apply to members covered by the Blue Cross and Blue Shield Federal Employee Program®, the Michigan Education Special Services Association or UAW Retiree Medical Benefits Trust non-Medicare members

For details on the preferred and nonpreferred filgrastim products, refer to the August 2020 Record article.

As a reminder, authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.


Some drugs won’t be payable when administered by a health care provider to Blue Cross and BCN commercial members

For dates of service on or after April 1, 2021, the medications listed below won’t be payable by Blue Cross Blue Shield of Michigan and Blue Care Network when administered by a physician or other health care professional.

This change affects Blue Cross commercial and Blue Care Network commercial members. The reason for the change is that these drugs can safely and conveniently be self-administered by the member in the member’s home. They don’t require administration by a health care professional.

The following drugs are currently payable under either the medical benefit or the pharmacy benefit. Starting April 1, they’re payable only under the pharmacy benefit.

  • Actimmune® (interferon gamma-1b), HCPCS code J9216
  • Akynzeo® (netupitant / palonosetron), HCPCS code J8655
  • Arcalyst® (rilonacept), HCPCS code J2793
  • Banophen™ / Ormir™ / Pharbedryl™ (diphenhydramine), HCPCS code Q0163
  • Emend® (aprepitant), HCPCS code J8501
  • Imitrex® (sumatriptan succinate), HCPCS code J3030
  • Granisetron HCl® (granisetron hydrochloride), HCPCS code Q0166 / S0091
  • Marinol® / Syndros® (dronabinol), HCPCS code Q0167
  • Megestrol acetate®, HCPCS code S0179
  • Pegasys® (peginterferon alfa-2a), HCPCS code S0145
  • Pegintron® (peginterferon alfa-2b), HCPCS code S0148
  • Promethazine HCl® (phenadoz), HCPCS code Q0169
  • Regranex® (becaplermin), HCPCS code S0157
  • Sensipar® (cinacalcet), HCPCS code J0604
  • Varubi® (rolapitant), HCPCS code J8670
  • Zofran® / Zuplenz® (ondansetron), HCPCS code Q0162 / S0119

There are no other changes that apply to the management of these therapies at this time.

For more information

To view requirements for drugs covered under the pharmacy benefit, see the Blue Cross and BCN Prior authorization and step therapy coverage criteria document. This document is available from the following pages on the ereferrals.bcbsm.com website:

For a list of requirements related to drugs covered under the medical benefit, see the Blue Cross and BCN utilization management medical drug list for Blue Cross PPO (commercial) and BCN HMO (commercial) members document.

We’ll update the requirements lists with the new information prior to April 1, 2021.


Quarterly update: Requirements changed for some commercial medical benefit drugs

Blue Cross Blue Shield of Michigan and Blue Care Network encourage proper utilization of high-cost medications that are covered under the medical benefit. As part of this effort, we maintain a comprehensive list of requirements for both Blue Cross and BCN commercial members.

During the fourth quarter of 2020, there were changes to prior authorization requirements, site-of-care requirements or both for Blue Cross commercial members for the following medical benefit drugs:

HCPCS code Brand name Generic name
J0596

Ruconest®

c-1 inhibitor recombinant
J0597

Berinert®

c-1 esterase
J0598

Cinryze®

c-1 esterase
J1290

Kalbitor®

ecallantide
J1442

Neupogen®

filgrastim
J1447

Granix®

tbo-filgrastim
J1444

Firazyr®

icatibant
J1444

Icatibant

icatibant hcl

For a detailed list of requirements, see the Blue Cross and BCN utilization management medical drug list.

This list is available on the Blue Cross Medical Benefit Drugs page at ereferrals.bcbsm.com.

These authorization requirements apply only to groups that currently participate in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. To view the list of Blue Cross commercial groups that don’t participate in the program, see the Specialty Pharmacy Prior Authorization Master Opt-in/out Group List.

As a reminder, an authorization approval isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.

No portion of this publication may be copied without the express written permission of Blue Cross Blue Shield of Michigan, except that BCBSM participating health care providers may make copies for their personal use. In no event may any portion of this publication be copied or reprinted and used for commercial purposes by any party other than BCBSM.

*CPT codes, descriptions and two-digit numeric modifiers only are copyright 2020 American Medical Association. All rights reserved.