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March 2024

Pemfexy to have step therapy requirements starting in April

Members must try and fail two other pemetrexed drugs before we’ll approve prior authorization requests for Pemfexy® (pemetrexed), HCPCS code J9304, for dates of service on or after April 26, 2024.

Members must try and fail two of the following drugs:

  • Alimta® (pemetrexed), HCPCS code J9305
  • Pemrydi® RTU (pemetrexed), HCPCS code J9324
  • Pemetrexed (generic, various brands), HCPCS codes J9294, J9296, J9297, J9314, J9322, J9323

These drugs are covered under the members’ medical benefits, not their pharmacy benefits.

All of the drugs listed above continue to require prior authorization through Carelon Medical Benefits Management, as specified in the pertinent drug lists, which are linked below. We’ll update these lists to reflect the new step therapy requirement prior to the effective date.

Prior authorization isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.

Members affected by this change

This new requirement applies to:

  • Blue Cross Blue Shield of Michigan commercial:
  • Blue Care Network commercial members
  • Medicare Plus Blue℠ members
  • BCN Advantage℠ members

More about the prior authorization requirements
For a full list of requirements related to drugs covered under the medical benefit, see the following lists:

Carelon Medical Benefits Management is an independent company that contracts with Blue Cross Blue Shield of Michigan and Blue Care Network to manage prior authorizations for select services.

No portion of this publication may be copied without the express written permission of Blue Cross Blue Shield of Michigan, except that BCBSM participating health care providers may make copies for their personal use. In no event may any portion of this publication be copied or reprinted and used for commercial purposes by any party other than BCBSM.

*CPT codes, descriptions and two-digit numeric modifiers only are copyright 2023 American Medical Association. All rights reserved.