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April 2024

Starting April 1, additional preferred product required for Soliris, Ultomiris for most commercial members

For dates of service on or after April 1, 2024, step therapy requirements will change for Soliris® (eculizumab), HCPCS code J1300, and Ultomiris® (ravulizumab), HCPCS code J1303.

Preferred products for Soliris and Ultomiris

Before April 1, 2024

On or after April 1, 2024

Members must try and fail:

  • Vyvgart®

Members must try and fail both:

  • Rystiggo®
  • Either Vyvgart or Vyvgart Hytrulo


This change affects Blue Cross Shield of Michigan commercial members and Blue Care Network commercial members.

By April 1, we’ll update the Blue Cross and BCN utilization management medical drug list to reflect the new preferred drugs.

The drugs discussed above continue to require prior authorization through the NovoLogix® online tool.

Some Blue Cross commercial groups aren’t subject to these requirements

For Blue Cross commercial groups, this prior authorization requirement applies only to groups that participate in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. To determine whether a group participates in the prior authorization program, see the Specialty Pharmacy Prior Authorization Master Opt-in/out Group list.

Note: Blue Cross and Blue Shield Federal Employee Program® members and UAW Retiree Medical Benefits Trust (non-Medicare) members don’t participate in the standard prior authorization program.

Additional information

For more information about medical benefit drugs, see the following pages on ereferrals.bcbsm.com:

Prior authorization isn’t a guarantee of payment. Health care practitioners need to verify eligibility and benefits for members.

No portion of this publication may be copied without the express written permission of Blue Cross Blue Shield of Michigan, except that BCBSM participating health care providers may make copies for their personal use. In no event may any portion of this publication be copied or reprinted and used for commercial purposes by any party other than BCBSM.

*CPT codes, descriptions and two-digit numeric modifiers only are copyright 2023 American Medical Association. All rights reserved.