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February 2022

Ryplazim requires prior authorization for Medicare Advantage members

For dates of service on or after Jan. 17, 2022, Ryplazim® (plasminogen, human-tvmh), HCPCS code J3590, requires prior authorization through the NovoLogix® online tool. This requirement applies to Medicare Plus Blue℠ and BCN Advantage℠ members.

Prior authorization is required when this drug is administered in any site of care other than inpatient hospital (place of service code 21) and is billed as follows:

  • Electronically through an 837P transaction or on a professional CMS-1500 claim form
  • Electronically through an 837I transaction or by using the UB04 claim form for a hospital outpatient type of bill 013x

Submitting prior authorization requests

Submit prior authorization requests for this drug through NovoLogix. It offers real-time status checks and immediate approvals for certain medications.

If you have access to Provider Secured Services, you already have access to NovoLogix. If you need to request access to Provider Secured Services, complete the Provider Secured Access Application form and fax it to the number on the form.

List of requirements

For a list of requirements related to drugs covered under the medical benefit, please see the Medical Drug and Step Therapy Prior Authorization List for Medicare Plus Blue PPO and BCN Advantage members.

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*CPT codes, descriptions and two-digit numeric modifiers only are copyright 2021 American Medical Association. All rights reserved.