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July 2020

All Providers

Here’s an update on temporary changes due to COVID-19 pandemic

Blue Cross Blue Shield of Michigan and Blue Care Network have made many temporary changes to support providers and protect members during the COVID-19 pandemic. Some of those changes have ended and one has been extended.

These updates apply to Blue Cross commercial, BCN commercial, Medicare Plus BlueSM and BCN AdvantageSM members, unless otherwise noted.

Temporary changes that have ended
For dates of service on or after June 13, 2020 Clinical review is again required by Blue Cross/BCN Utilization Management for acute care admissions with non-COVID-19-related diagnoses. You’ll need to submit clinical documentation along with your authorization requests.
For dates of service on or after July 1, 2020

Member cost share once again applies for Blue Cross commercial and BCN commercial members for common medical and behavioral health visits that are performed using telemedicine.
Notes:

  • As indicated in the second section of this chart, we’ll continue to waive cost share for COVID-19-related treatment through Dec. 31, 2020. This includes COVID-19-related treatment delivered through telemedicine.
  • For Medicare Plus Blue and BCN Advantage members, cost share will be waived for common medical and behavioral health services through Dec. 31, 2020, for both in-office and telehealth visits. See Blue Cross and BCN waiving cost share for Medicare Advantage members for more information.
For acute care admissions with COVID-19-related diagnoses, clinical review is once again required.
For CT scans of the chest to rule out pneumonia diagnosis associated with COVID-19, AIM Specialty Health® again requires clinical review for procedure codes *71250, *71260 and *71270.
For the first three days of admission to a skilled nursing facility for members transferred from acute care, Blue Cross/BCN Utilization Management and naviHealth once again require clinical review.

For Blue Cross and BCN-primary original claims with submission deadlines of Oct. 1, 2020, and after

The 90-day extension to claim submission time limits, which was in effect for original claims with submission deadlines of Jan. 1, 2020, and after, will end Sept. 30.

For primary original claims with submission deadlines of Oct. 1, 2020, and after, existing participation/affiliation agreement submission deadlines apply for all lines of business, including Blue Cross commercial, BCN commercial, Medicare Plus Blue and BCN Advantage.



Temporary change that has been extended
End date extended from June 30, 2020, to until further notice

For Blue Cross’ commercial and BCN commercial members, we’ll waive member cost share for COVID-19 treatment through Dec. 31, 2020. Previously, this was scheduled to end on June 30, 2020.

As previously communicated, we’ll continue to waive cost share for COVID-19 treatment through Dec. 31, 2020, for Medicare Plus Blue and BCN Advantage members. See Blue Cross and BCN waiving cost share for Medicare Advantage members for more information.

To determine end dates for other temporary actions Blue Cross and BCN have taken, see the Temporary changes due to the COVID-19 pandemic document. You can find this document on our public website at bcbsm.com/coronavirus and through Provider Secured Services.


We’ve created billing tips for COVID-19 diagnosis codes

We’ve experienced many changes during the COVID-19 pandemic. To make billing easier for you, we’ve created two reference documents:

Two diagnosis codes for confirmed COVID-19 for dates of service prior to April 1, 2020, were not included in the chart of diagnosis codes in the May Record article on COVID-19 billing guidelines. Please refer to the Billing tips for COVID-19 for a complete list of diagnosis codes for COVID-19.

The billing tips documents can be found on our Coronavirus (COVID-19) information updates for providers page. Log in as a provider at bcbsm.com and click on Coronavirus (COVID-19). You can also find information at bcbsm.com/coronavirus by clicking on For Providers.


COVID-19 HCPCS and CPT codes added

The Centers for Medicare & Medicaid Services has added a new COVID-19 code as part of its quarterly Health Care Procedure Coding System updates. The code, effective date and Blue Cross Blue Shield of Michigan’s coverage decisions are below.

HCPCS code: Pathology and Laboratory

Code Change Coverage comments Effective date
C9803 Added Covered for facility only March 1, 2020

There is also a new COVID-19-related CPT code as follows:

CPT code: Pathology and Laboratory

Proprietary Laboratory Analysis Code

Code Change Coverage comments Effective date
0202U Added Covered May 20, 2020

None of the information included in this article is intended to be legal advice and, as such, it remains the provider’s responsibility to ensure that all coding and documentation are done in accordance with all applicable state and federal laws and regulations.


Changes to Michigan’s auto no-fault insurance law may increase need for coordination of benefits

Effective with auto insurance policies issued or renewed after July 1, 2020, individuals will no longer be required to carry unlimited personal injury protection, or PIP, with their auto insurance. Under certain circumstances, drivers can select different levels — or opt out — of PIP coverage through their auto insurer.

In situations where a member’s auto insurance is considered primary to their Blue Cross Blue Shield of Michigan coverage — and they select a level of PIP coverage that’s less than unlimited — their auto insurance benefits may run out. These changes to Michigan’s auto no-fault insurance law may lead to more instances where providers need to coordinate benefits for their patients.

More of what you need to know

  • Continue to bill auto accidents as you do today.
  • Enter the appropriate value indicating an auto-accident claim.
  • Continue to follow existing Medicare guidelines pertaining to billing and secondary payer rules.
  • PIP is a “lifetime per accident per patient” benefit, not an “annual per family or per individual” maximum.
  • PIP coverage pays for some items that health insurance doesn’t, such as attendant care, lost wages and vehicle or housing modifications. (PIP also pays for services that Medicare coverage may not, such as transportation to and from medical appointments and vehicle modifications.)
  • If the auto insurer is considered the primary payer, Blue Cross will reject the claim if we’re billed as primary payer.
  • When the member’s auto PIP benefits are exhausted, you’ll receive a rejection from the auto insurer. (PR*119 or PR*149 may be indicated on the 835 denial.) You can then bill Blue Cross, indicating Blue Cross is secondary.
  • When you bill Blue Cross as a secondary payer, you’ll need to include the primary auto insurer name along with the primary auto insurance claim decision resolution (value code) on the 837.

Determining which insurance is primary

Provider should ask members:

  • Do you have coverage from more than one insurance carrier?
  • Is your injury the result of an accident?
  • Does your medical coverage have any restrictions, such as not paying for claims related to an auto accident or paying secondary only?

Note: In most cases, Blue Cross is the primary payer and health care providers will continue to bill Blue Cross first.

If you need more information about how Blue Cross coordinates auto insurance benefits, refer to the Blue Cross PPO (Commercial) Provider Manual by logging in to Provider Secured Services. Refer to the auto insurance section of the Coordination of Benefits chapter.

If you have questions about coordinating benefits with a member’s existing auto insurer, call Provider Inquiry. Professional providers can call Provider Inquiry at 1-800-344-8525 and hospital and other facility providers can call 1-800-249-5103.


Blue Cross recognized by J.D. Power for highest member satisfaction among commercial health plans in Michigan

Putting members first is a hallmark of our work at Blue Cross Blue Shield of Michigan. That’s why we at Blue Cross are honored to receive the J.D. Power Award for highest member satisfaction among commercial health plans in Michigan for the second time in three years.

We want to thank our health care providers for the role they’ve played in helping us achieve this honor. The experience members have in provider practices and hospitals influences their impression of Blue Cross.

This award is given to the Michigan health plan that ranks first place overall in the J.D. Power 2020 Commercial Member Health Plan study. It recognizes our efforts at Blue Cross to make sure our members are taken care of with the right care at the right time.

Improving the experience for members has been the focus of many Blue Cross initiatives throughout the past few years. Those include:

  • Making health care more affordable through Value-Based Contracting and  Blueprint for Affordability
  • Working closely with health care providers to improve health care quality through our Physicians Group Incentive Program and Collaborative Quality Initiatives
  • Launching programs to support care management and diabetes management
  • Improving access to health care through the Blue Cross Online Visits app
  • Enhancing our Blue Cross mobile app and bcbsm.com with the new MIBlue Virtual Assistant chat feature, which enables members to get answers to their health plan questions 24/7

We appreciate the care you give to your patients — our members — and your ongoing efforts to improve health care quality and affordability.

Blue Cross Blue Shield of Michigan received the highest score in Michigan in the J.D. Power 2020 U.S. Member Health Plan Study of customers’ satisfaction with their commercial health plan. Visit jdpower.com/awards.


Blue Cross and BCN waiving cost share for Medicare Advantage members

As announced on May 7, Blue Cross Blue Shield of Michigan and Blue Care Network are waiving cost share for their Medicare Advantage individual and fully insured group members for certain in-person and virtual services. Members won’t be liable for any copays, coinsurance or deductibles for the following network services from May 1 through Dec. 31, 2020:

  • In-person primary care services, including laboratory testing processed in the office and radiology services performed in the office
  • Behavioral health office visits
  • Telehealth services for both medical and behavioral health

Some Medicare Advantage groups are still making decisions on this waiver, and we’ll give further guidance as soon as possible for those groups.

During the COVID-19 state of emergency, cost share for these services will also be waived for out-of-network services. Medicare Advantage organizations are required to provide the same cost sharing for the enrollee at a non-contracted facility as if the service or benefit had been furnished at a plan-contracted facility.

The waiving of member cost share will be calculated accurately on the remittance advice but may not be reflected when checking benefits in our systems.

In-person medical services

BCN AdvantageSM members: Cost share is waived for any in-person medical services provided by the member’s primary care provider.

Medicare Plus BlueSM members: Cost share is waived for all in-person medical services billed with a rendering provider based on the designations below with the following places of service: 03, 11, 12, 13, 14, 15, 19, 22, 34, 49, 50, 71 and 72.

  • Certified nurse specialist
  • General practice
  • Geriatric medicine
  • Family nurse practitioner
  • Family practice
  • Internal medicine
  • Obstetrics/gynecology
  • Nurse practitioner
  • Pediatric medicine
  • Pediatric nurse practitioner
  • Physician assistant

Member cost share isn’t waived for:

  • Services provided by medical specialists other than the provider types listed above
  • Services provided in urgent care centers
  • Laboratory services ordered by a physician and sent to an outside laboratory provider (other than COVID-19 testing)
  • Medicare Part B medications administered in the office
  • Supplies received from the physician in the office

In-person behavioral health services

Member cost sharing is waived for Medicare Advantage members seeking behavioral health services in a physician’s office including individual therapy, psychiatric medication consultation and group therapy.

BCN Advantage members: Evaluation and management services are covered at no cost share for the following diagnoses:

  • F10-F1999
  • F55-F558
  • F01-F09
  • F20-F54
  • F59-F99

Medicare Plus Blue members: Evaluation and management services are covered at no cost share when used with the following specialties:

  • Psychiatry
  • Clinical psychologist (billing independently)
  • Addiction medicine
  • Licensed clinical social worker
  • Neuropsychiatry
  • Adult psychiatric mental health nursing

The following are CPT codes for behavioral health in-person visits covered with no cost share for both Medicare Plus Blue and BCN Advantage members:

Evaluation and management services: *99201-*99205, *99211-*99215

Other: *90791, *90792, *90832, *90833, *90834, *90836, *90837, *90838, *90846, *90847, *90853, *96101, *96102, *96111, *90839, *90840, *90849

Telehealth services

On April 30, the Centers for Medicare & Medicaid Services further expanded the list of services covered through telehealth to allow providers to care for patients and mitigate the risk of spreading the coronavirus. Clinicians can provide these services to new or established patients.

Blue Cross and BCN are waiving cost share for telehealth services for both medical and behavioral health for their Medicare Advantage members effective March 16 through Dec. 31. Medicare Plus Blue and BCN Advantage members can receive telehealth and other communications technology-based services wherever they are located. As mentioned earlier in this article, some self-funded Medicare Advantage groups are still making decisions on this waiver but have waived cost share through at least June 30 for these telehealth services. We’ll give further guidance as soon as possible for those groups.

Refer to our Telehealth procedure codes for COVID-19 document for the list of covered telehealth services for our Medicare Advantage members as well as Blue Cross commercial and BCN commercial members.


We invite you to join PGIP as a physician organization

Our Physician Group Incentive Program offers incentives to participating practitioners, physician organizations and organized systems of care for improving health care delivery. We’re pleased to announce that we’ll accept applications for PGIP from new POs from Aug. 1 through Aug. 31, 2020.

To request application materials, send an email to valuepartnerships@bcbsm.com.

A PGIP physician organization consists of Blue Cross Blue Shield of Michigan TRUST or Traditional network physicians working together to:

  • Transform systems of care to effectively manage patient populations.
  • Build the infrastructure needed to optimize, measure and monitor quality of care.
  • Promote collaborative relationships.
  • Support the most cost-effective delivery of services to improve patient outcomes.

About PGIP
PGIP is an innovative provider program developed with input from providers across Michigan to help improve the quality and efficiency of health care in the state. PGIP facilitates change through approximately 20 initiatives, including our nationally recognized Patient-Centered Medical Home program. PGIP rewards physician organizations and organized systems of care for improving health care delivery to their attributed patient population.

If you’re interested in participating in PGIP as an individual practitioner, click here to learn more about PGIP physician organizations.

For more information on PGIP, visit the Physician Group Incentive Program section of valuepartnerships.com.


Vaccine Affiliation Agreement amended

We’re amending our Vaccine Affiliation Program to permit pharmacies participating in the program to submit medical claims to Blue Care Network for services listed on the Medical Immunization Pharmacy Providers Payable Vaccines Fee Schedule, which is updated occasionally.

Our Vaccine Affiliation Agreement remains unchanged for Blue Cross Blue Shield of Michigan members.

A previous amendment to the agreement expanded the program to pharmacies participating with BCN with certain exceptions. One of the exceptions was that covered services for BCN members were limited to adult immunizations only.

The Second Amendment to the Vaccine Affiliation Agreement removes this limitation and now provides that covered services for BCN members include adult immunizations and certain other testing as described in the fee schedule, subject to the other terms and conditions of the agreement.

As background, we announced in The Record in 2016 that Blue Cross members could get select vaccines under the pharmacy benefit starting Oct. 1, 2016.


2020 second-quarter CPT update: New and deleted codes

Pathology and laboratory
Proprietary laboratory analysis codes

Code Change Coverage comments Effective date
0124U Deleted Deleted June 30, 2020
0125U Deleted Deleted June 30, 2020
0126U Deleted Deleted June 30, 2020
0127U Deleted Deleted June 30, 2020
0128U Deleted Deleted June 30, 2020
0172U Added Not covered July 1, 2020
0173U Added Not covered July 1, 2020
0174U Added Not covered July 1, 2020
0175U Added Not covered July 1, 2020
0176U Added Not covered July 1, 2020
0177U Added Covered July 1, 2020
0178U Added Not covered July 1, 2020
0179U Added Not covered July 1, 2020
0180U Added Not covered July 1, 2020
0181U Added Not covered July 1, 2020
0182U Added Not covered July 1, 2020
0183U Added Not covered July 1, 2020
0184U Added Not covered July 1, 2020
0185U Added Not covered July 1, 2020
0186U Added Not covered July 1, 2020
0187U Added Not covered July 1, 2020
0188U Added Not covered July 1, 2020
0189U Added Not covered July 1, 2020
0190U Added Not covered July 1, 2020
0191U Added Not covered July 1, 2020
0192U Added Not covered July 1, 2020
0193U Added Not covered July 1, 2020
0194U Added Not covered July 1, 2020
0195U Added Not covered July 1, 2020
0196U Added Not covered July 1, 2020
0197U Added Not covered July 1, 2020
0198U Added Not covered July 1, 2020
0199U Added Not covered July 1, 2020
0200U Added Not covered July 1, 2020
0201U Added Not covered July 1, 2020

Category III
Surgery

Code Change Coverage comments Effective date
0594T Added Not covered July 1, 2020
0614T Added Not covered July 1, 2020
0619T Added Not covered July 1, 2020

Category III
Surgery/Eye and ocular adnexa

Code Change Coverage comments Effective date
0617T Added Not covered July 1, 2020
0618T Added Not covered July 1, 2020

Category III
Surgery
Eye and ocular adnexa intraocular lens procedure

Code Change Coverage comments Effective date
0616T Added Not covered July 1, 2020

Category III codes
Cardiovascular services

Code Change Coverage comments Effective date
0607T Added Not covered July 1, 2020
0608T Added Not covered July 1, 2020

Category III
Medicine
Ophthalmology

Code Change Coverage comments Effective date
0604T Added Not covered July 1, 2020

Category III
Medicine
Ophthalmology special ophthalmological services

Code Change Coverage comments Effective date
0605T Added Not covered July 1, 2020
0606T Added Not covered July 1, 2020

Category III
Other medical service

Code Change Coverage comments Effective date
0602T Added Not covered July 1, 2020
0603T Added Not covered July 1, 2020

Category III
Surgery digestive

Code Change Coverage comments Effective date
0600T Added Not covered July 1, 2020
0601T Added Not covered July 1, 2020

Category III
Diagnostic services
Active wound care Management

Code Change Coverage comments Effective date
0598T Added Not covered July 1, 2020
0599T Added Not covered July 1, 2020

Category III
Surgery urinary

Code Change Coverage comments Effective date
0596T Added Not covered July 1, 2020
0597T Added Not covered July 1, 2020

Category III
Medicine

Code Change Coverage comments Effective date
0615T Added Not covered July 1, 2020

Category III
Surgery cardiovascular

Code Change Coverage comments Effective date
0613T Added Not covered July 1, 2020

Category III
Diagnostic radiology

Code Change Coverage comments Effective date
0609T Added Not covered July 1, 2020
0610T Added Not covered July 1, 2020
0611T Added Not covered July 1, 2020
0612T Added Not covered July 1, 2020

None of the information included in this article is intended to be legal advice and, as such, it remains the provider’s responsibility to ensure that all coding and documentation are done in accordance with all applicable state and federal laws and regulations.


2020 HCPCS update: New code added

The Centers for Medicare & Medicaid Services has added a new code as part of its quarterly Health Care Procedure Coding System updates. The code, effective date and Blue Cross Blue Shield of Michigan’s coverage decision are below.

Code Change Coverage comments Effective date
G2025 Added Covered Jan. 27, 2020

None of the information included in this article is intended to be legal advice and, as such, it remains the provider’s responsibility to ensure that all coding and documentation are done in accordance with all applicable state and federal laws and regulations.


Billing chart: Blues highlight medical, benefit policy changes

You’ll find the latest information about procedure codes and Blue Cross Blue Shield of Michigan billing guidelines in the following chart.

This billing chart is organized numerically by procedure code. Newly approved procedures will appear under the New Payable Procedures heading. Procedures for which we have changed a billing guideline or added a new payable group will appear under Updates to Payable Procedures. Procedures for which we are clarifying our guidelines will appear under Policy Clarifications. New procedures that are not covered will appear under Experimental Procedures.

You will also see that descriptions for the codes are no longer included. This is a result of recent negotiations with the AMA on use of the codes.

We will publish information about new BCBS groups or changes to group benefits under the Group Benefit Changes heading.

For more detailed descriptions of the BCBSM policies for these procedures, please check under the Medical/Payment Policy tab in Explainer on web-DENIS. To access this online information:

  • Log in to web-DENIS.
  • Click on BCBSM Provider Publications & Resources.
  • Click on Benefit Policy for a Code.
  • Click on Topic.
  • Under Topic Criteria, click on the drop-down arrow next to Choose Identifier Type and then click on HCPCS Code.
  • Enter the procedure code.
  • Click on Finish.
  • Click on Search.
Code* BCBSM changes to:
Basic Benefit and Medical Policy, Group
Variations Payment Policy, Guidelines
UPDATES TO PAYABLE PROCEDURES

J3490
J3590

Basic benefit and medical policy

Avsola (infliximab-axxq)

Avsola (infliximab-axxq) is payable when billed for FDA-approved indications, effective Dec. 6, 2019. Avsola (infliximab-axxq) should be reported with procedure code J3490 or J3590 and the appropriate national drug code until a permanent code is established.

URMBT groups are excluded from coverage of this drug. 

Avsola (infliximab-axxq) is a biosimilar to Remicade (infliximab). It’s a tumor necrosis factor, or TNF, blocker indicated for the following:

  • Crohn’s disease
  • Pediatric Crohn’s disease
  • Ulcerative colitis
  • Pediatric ulcerative colitis
  • Rheumatoid arthritis in combination with methotrexate
  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Plaque psoriasis

Dosage and administration:

Avsola (infliximab-axxq) is administered by intravenous infusion over a period of not less than two hours.

Crohn’s disease: 5 mg/kg at zero, two and six weeks, then every eight weeks. Some adult patients who initially respond to treatment may benefit from increasing the dose to 10 mg/kg if they later lose their response.

Pediatric Crohn’s disease: 5 mg/kg at zero, two and six weeks, then every eight weeks.

Ulcerative colitis: 5 mg/kg at zero, two and six weeks, then every eight weeks.

Pediatric ulcerative colitis: 5 mg/kg at zero, two and six weeks, then every eight weeks.

Rheumatoid arthritis: In conjunction with methotrexate, 3 mg/kg at zero, two and six weeks, then every eight weeks. Some patients may benefit from increasing the dose up to 10 mg/kg or treating as often as every four weeks.

Ankylosing spondylitis: 5 mg/kg at zero, two and six weeks, then every six weeks.

Dosage forms and strengths:

For injection: 100 mg of lyophilized infliximab-axxq in a 20 mL single-dose vial for intravenous infusion.

J3490
J3590

Basic benefit and medical policy

Barhemsys (amisulpride)

Barhemsys (amisulpride) is payable when billed for the FDA-approved indications, effective Feb. 26, 2020. Barhemsys (amisulpride) should be reported with procedure code J3490 or J3590 and the appropriate national drug code until a permanent code is established.

URMBT groups are excluded from coverage of this drug. 

Barhemsys (amisulpride) is a dopamine-2, or D2, antagonist indicated in adults for:

  • Prevention of postoperative nausea and vomiting, or PONV, either alone or in combination with an antiemetic of a different class.
  • Treatment of PONV in patients who have received antiemetic prophylaxis with an agent of a different class or haven’t received prophylaxis.

Dosage and administration:

Prevention of PONV, either alone or in combination with another antiemetic: 5 mg as a single intravenous dose infused over one to two minutes at the time of induction of anesthesia.

Treatment of PONV: 10 mg as a single intravenous dose infused over one to two minutes in the event of nausea and/or vomiting after a surgical procedure.

Dosage forms and strengths

Injection: 5 mg/2 mL (2.5 mg/mL) in a single-dose vial.

J9271

Basic benefit and medical policy

Keytruda (pembrolizumab)

Payable diagnoses for Keytruda (pembrolizumab) have been updated. Diagnosis 15.8 and C69.92 have been added as payable for Keytruda (pembrolizumab).
POLICY CLARIFICATIONS

Established
0191T, 0376T, 66179, 66180, 66183, 66184, 66185, 66982, 66983, 66984, 0449T, 0450T, 0474T

Experimental
66999, 0253T

Basic benefit and medical policy

Aqueous Shunts and Stents for Glaucoma policy

The criteria have been updated for the Aqueous Shunts and Stents for Glaucoma policy. Procedure code 0376T is now payable when billed in conjunction with procedure code 0191T.

If procedure code 0376T is billed alone or with any other procedure code, it should remain experimental.

Inclusions:

Insertion of FDA-approved aqueous shunts is considered established as a method to reduce intraocular pressure in patients with mild to moderate open-angle glaucoma when conventional pharmacologic treatments have failed to control intraocular pressure adequately.  

Currently available FDA-approved shunts include:

  • Ahmed™ glaucoma implant
  • Baerveldt® seton
  • Ex-PRESS® mini glaucoma shunt
  • Glaucoma pressure regulator
  • Krupin-Denver valve implant
  • Molteno® implant
  • Schocket shunt
  • Xen® Gel Stent
  • CyPass® Micro-Stent (recalled)
  • iStent®
  • iStent inject®
  • Hydrus™

Note: The CyPass Micro-Stent (recalled), iStent and Hydrus are indicated for use in conjunction with cataract surgery for the reduction of IOP in adult patients with mild to moderate primary open-angle glaucoma.

The iStent Inject comes pre-loaded with two stents.

Exclusions:

  • The use of an aqueous shunt for all other conditions, including patients with glaucoma when intraocular pressure is controlled by medications
  • Insertion of aqueous shunts that aren’t FDA approved
  • For the iStent Micro Bypass Stent, patients with the following conditions aren’t appropriate candidates and the insertion of this stent would be considered experimental:
    • In children
    • In eyes with significant prior trauma
    • In eyes with abnormal anterior segment
    • In eyes with chronic inflammation
    • In glaucoma associated with vascular disorders
    • In pseudophakic patients with glaucoma
    • In uveitic glaucoma
    • In eyes with prior incisional glaucoma surgery or cilioablative procedures
    • In eyes with prior laser trabeculectomy with selective LT within 90 days prior to screening or prior to argon laser trabeculectomy at any time
    • In patients with medicated intraocular pressure greater than 24 mm Hg
    • In patients with unmedicated IOP less than 21 mm Hg nor greater than 36 mm Hg after "washout" of medications
    • After complications during cataract surgery, including but not limited to, severe corneal burn, vitreous removal/vitrectomy required, corneal injuries, or complications requiring the placement of an anterior chamber IOL (intraocular lens)
    • When implantation has been without concomitant cataract surgery with IOL implantation for visually significant cataract
    • In patients with pseudoexfoliative glaucoma or pigmentary glaucoma, or in patients with other secondary open-angle glaucoma
  • For the iStent Inject, patients with the following conditions are not appropriate candidates and the insertion of this stent would be considered experimental:
    • Quick or sudden increase in eye pressure
    • Inflammation of the eye tissue (uvea)
    • Neovascular glaucoma
    • Noticeable birth irregularities on the front of the eye
    • Orbital tumor
    • Thyroid eye disease
    • Sturge-Weber syndrome
    • Any other type of condition that may cause elevated pressure in the veins of the eye
  • For the Hydrus Microstent, patients with the following conditions aren’t appropriate candidates and the insertion of this stent would be considered experimental:
    • When the colored part of the eye (iris) is pushed up against the drainage pathway or when other material blocks the drainage pathway
    • Traumatic glaucoma, malignant glaucoma or inflammation of the eye tissue
    • Glaucoma associated with the growth of abnormal blood vessels in the eye
    • Noticeable birth irregularities of the anterior chamber angle

The policy effective date is Nov. 1, 2019.

20930, 20931, 20939, 20999, 0565T, 0566T

Procedures added
20930, 20931, 0565T, 0566T

Basic benefit and medical policy

Orthopedic Applications of Stem-Cell Therapy (including Allografts and Bone Substitutes used with Autologous Bone Marrow) policy

New procedure codes have been added to the Orthopedic Applications of Stem-Cell Therapy (including Allografts and Bone Substitutes used with Autologous Bone Marrow) policy.

Medical policy statement

Mesenchymal stem cell therapy is considered experimental for all orthopedic applications, including use in repair or regeneration of musculoskeletal tissue.

Allograft bone products containing viable stem cells, including but not limited to demineralized bone matrix with stem cells, are considered experimental for all orthopedic applications.

Allograft or synthetic bone graft substitutes that must be combined with autologous blood or bone marrow are considered experimental for all orthopedic applications.

The safety and efficacy of these treatments haven’t been established.

The policy effective date is July 1, 2020.

66820, 66821, 66830, 66840, 66850, 66852, 66920, 66930, 66940, 66982, 66983, 66984, 66987, 66988

Basic benefit and medical policy

Cataract removal surgery

The safety and efficacy of cataract removal surgery, with or without intraocular lens, or IOL, implantation, have been established. It’s considered an effective treatment when clinical criteria are met.

Policy criteria have been updated regarding intraocular lenses, effective July 1, 2020.

Inclusions:

Cataract removal surgery (with or without IOL implantation) may be an appropriate treatment for adult members when all the following criteria are met:

  • The patient has a decreased ability to carry out activities of daily living such as reading, watching television, driving or meeting occupational or vocational expectations.
  • The patient has a best corrected visual acuity of 20/40 or worse at distance or near; or additional testing reveals one of the following:
    • Consensual light testing decreases visual acuity by two lines
    • Glare testing decreases visual acuity by two lines
  • Other eye diseases, such as macular degeneration or diabetic retinopathy, have been ruled out as the only cause of decreased visual function.
  • Significant improvement in visual function can be expected as a result of cataract extraction.
  • The patient has undergone a preoperative ophthalmologic evaluation that includes a comprehensive ophthalmologic exam and ophthalmic biometry
  • If cataracts exist in both eyes and require surgery, the surgery will be performed on each eye at separate times, usually four to eight weeks apart.
  • The patient has been educated about the risks and benefits of cataract surgery and the alternatives to surgery (e.g., avoidance of glare, optimal eyeglass prescription, etc.).

Additional indications for cataract removal may include:

  • Lens-induced disease or angle closure (phacomorphic glaucoma, phagolytic glaucoma, phacolysis, phacoanaphylaxis and other lens-induced disease may require cataract surgery and the need for extraction may be urgent)
  • The need to visualize the fundus (e.g., the patient has diabetes with significant risk of reduced visual acuity from diabetic retinopathy requiring management through visualization for diagnosis or clear media laser therapy)
  • Capsular rupture with lens swelling
  • Other trauma-induced ocular pathology necessitating surgery
  • Reduced contrast sensitivity that correlates with the patient’s subjective and objective assessments
  • Double vision in the affected eye
  • Clinically significant anisometropia in the presence of a cataract
  • The lens opacity interferes with optimal diagnosis or management of posterior segment conditions
  • Refractory correcting IOLs**

**Refractory correcting IOLs are considered deluxe items and are therefore considered not medically necessary. Patients must be advised in advance that deluxe or enhancement items are the financial responsibility of the member. It’s the providers’ responsibility to obtain a signed copy of the Advanced Notice of Member Responsibility form from the member and bill with the appropriate modifiers. Failure to appropriately execute an Advanced Notice of Member Responsibility form and bill with the correct modifiers will cause the claim to reject. The provider will be liable for the item and/or service and the member may not be billed.

For pediatric members, cataract removal surgery without IOL implantation may be considered an appropriate treatment when any of the following criteria are met:
 

  • Dense central opacity larger than 3 mm in diameter
  • In partial cataracts, surgery is indicated when the visual acuity is less than 6/18 or, in preverbal children, when fixation is poor
  • Capsular rupture with lens swelling
  • Other trauma-induced ocular pathology necessitating cataract surgery

Note: IOL implants are not FDA approved for children under the age 18.

Exclusions:

For adult members:

  • Glasses or visual aids provide functional vision satisfactory to the patient's needs and desires
  • Surgery isn’t expected to improve visual function, and no other indication for lens removal exists
  • The patient can’t safely undergo surgery because of coexisting medical or ocular conditions
  • Functional improvement is unlikely due to concomitant disease
  • Active proliferative diabetic retinopathy (unless cataract removal is necessary to allow visualization of the retina)
  • The presence of rubeosis iridis and/or neovascular glaucoma

For pediatric members:

  • IOLs haven’t received regulatory approval for use in children under the age of 18
  • The presence of a severe life-limiting disease
  • Cases of severe microphthalmia (corneal diameter less than 5 mm)
  • Cases in which the retina is irreparably detached or the posterior segment is disorganized
  • The presence of untreated retinoblastoma

Established codes:
78608, 78609, 78811, 78812, 78813, 78814, 78815, 78816, 78899, G0235, 78812, 78813, 78814, G0253
           
Other codes (experimental, not medically necessary, etc.):
G0219, G0252

Basic benefit and medical policy

Positron Emission Tomography for Oncologic Conditions policy

The criteria have been updated for the Positron Emission Tomography for Oncologic Conditions medical policy.

The policy is effective July 1, 2020.

General statements:

All inclusionary/exclusionary statements apply to both PET scans and PET/computed tomography scans, i.e., PET scans with or without PET/CT fusion.

A PET or PET/CT may be appropriate for a patient with known diagnosis of a malignancy to determine the optimal anatomic site for a biopsy or other invasive diagnostic procedure if standard imaging is equivocal. It also may replace conventional imaging when conventional imaging would be inadequate for accurate staging, and when clinical management will depend upon the stage of disease. In general, for most solid tumors, a tissue diagnosis is made prior to the performance of PET scanning. PET scans following a tissue diagnosis are performed for staging, not diagnosis. If the results of the PET scan won’t influence treatment decisions, these situations would be considered not medically necessary.

PET scans may be considered appropriate for the following oncologic conditions:

Anal cancer
Inclusions:

  • For the diagnosis, staging, restaging and monitoring of anal cancer

Exclusions:

  • Conditions not listed above

Bladder cancer
Inclusions:

  • For the staging or restaging of muscle invasive bladder cancer

Exclusions:

  • Conditions not listed above

Bone cancer
Inclusions:

  • For the staging of Ewing sarcoma and osteosarcoma

Exclusions:

  • For the staging of chondrosarcoma

Brain cancer
Inclusions:

  • For diagnosis and staging, where lesions metastatic from the brain are identified but no primary is found
  • For restaging, to distinguish recurrent tumor from radiation necrosis

Exclusions:

  • Conditions not listed above

Breast cancer
Inclusions:

  • Staging and restaging of breast cancer
  • Detecting locoregional or distant recurrence or metastasis (except axillary lymph nodes) when suspicion of disease is high and other imaging is inconclusive
  • Staging axillary lymph nodes

Exclusions:

  • For the differential diagnosis in patients with suspicious breast lesions or an indeterminate/low suspicion finding on mammography
  • For predicting pathologic response to neoadjuvant therapy for locally advanced disease

Cancer of unknown primary
Inclusions:

  • Patients with an unknown primary who meet all of the following criteria:
    • In patients with a single site of disease outside the cervical lymph nodes.
    • Patient is considering local or regional treatment for a single site of metastatic disease.
    • Patient has received a negative workup for a occult primary tumor.
    • The PET scan will be used to rule out or detect additional sites of disease that would eliminate the rationale for local or regional treatment.

Exclusions:

  • For patients with an unknown primary, including, but not limited to, the following:
    • As part of the initial workup of an unknown primary
    • As part of the workup of patients with multiple sites of disease

Cervical cancer
Inclusions:

  • For the initial staging of patients with locally advanced cervical cancer
  • For the evaluation of known or suspected recurrence

Exclusions:

  • For the initial diagnosis of cervical cancer in all other situations

Colorectal cancer
Inclusions:

  • Staging and restaging (initial and subsequent treatment strategy) to detect and assess resectability of hepatic or extrahepatic metastases of colorectal cancer
  • To evaluate a rising and persistently elevated carcinoembryonic antigen, or CEA, level when standard imaging, including CT scan, is negative

Exclusions:

  • When used as a technique to assess the presence of scarring versus local bowel recurrence in patients with previously resected colorectal cancer
  • When used as a technique contributing to radiotherapy treatment planning

Endometrial cancer
Inclusions:

  • Detection of lymph node metastases
  • Assessment of endometrial cancer recurrence

Exclusions:

  • Conditions not listed above

Esophageal cancer
Inclusions:

  • Staging and restaging of esophageal cancer 
  • Determining response to preoperative induction therapy

Exclusions:

  • Detection of primary esophageal cancer

Gastric (stomach) cancer
Inclusions:

  • Diagnosis, staging and restaging of gastric carcinoma if other imaging is inconclusive
  • Determining response to preoperative induction therapy

Exclusions:

  • Conditions not listed above

Head and neck cancer
Inclusions:

  • For the evaluation of the head and neck in the diagnosis of suspected head and neck cancer
  • For the initial staging of the disease
  • For restaging of residual or recurrent disease during follow up after treatment for their head and neck cancer

Exclusions:

  • Conditions not listed above

Hepatobiliary cancer
Inclusions:

  • When standard imaging studies are equivocal or nondiagnostic regarding extent of disease
  • When standard imaging prior to planned curative surgery has been performed and hasn’t demonstrated metastatic disease

Exclusions:

  • Conditions not listed above

Lung cancer
Inclusions:

  • Patients with a solitary pulmonary nodule as a single-scan technique (not dual-time) to distinguish between benign and malignant disease when prior CT scan and chest X-ray findings are inconclusive or discordant
  • To determine resect ability for patients with a presumed solitary metastatic lesion from lung cancer
  • As a staging or restaging technique in those with known non-small-cell lung cancer
  • PET scanning may be considered established in staging of small-cell lung cancer if limited stage is suspected based on standard imaging

Exclusions:

  • PET scanning in staging of small-cell lung cancer if extensive stage is established and in all other aspects of managing small-cell lung cancer
  • Conditions not listed above

Lymphoma, including Hodgkin’s disease
Inclusions:

  • PET scanning as a technique for staging lymphoma either during initial staging or for restaging at follow-up

Exclusions:

  • Conditions not listed above

Melanoma
Inclusions:

  • Assessing extranodal spread of malignant melanoma at initial staging or at restaging during follow-up treatment for advanced disease

Exclusions:

  • In managing Stage 0, I or II melanoma.
  • When used as a technique to detect regional lymph node metastases in patients with clinically localized melanoma who are candidates to undergo sentinel node biopsy

Multiple myeloma
Inclusions:

  • For the initial and subsequent treatment strategy of multiple myeloma

Exclusions:

  • Not applicable

Merkel cell carcinoma
Inclusions:

  • As clinically indicated

Neuroendocrine tumors
Inclusions:

  • For the diagnosis, staging, restaging and monitoring of neuroendocrine tumors

Exclusions:

  • Conditions not listed above

Ovarian cancer
Inclusions:

  • Initial staging of ovarian cancer.
  • For the evaluation of patients with signs or symptoms of suspected ovarian cancer recurrence (restaging) when standard imaging, including CT scan, is inconclusive

Exclusions:

  • For the initial evaluation (not staging) of known or suspected ovarian cancer in all other situations

Pancreatic cancer
Inclusions:

  • For the initial diagnosis and staging of pancreatic cancer when other imaging and biopsy are inconclusive

Exclusions:

  • Evaluating other aspects of pancreatic cancer

Penile cancer
Inclusions:

  • Staging inguinal lymph nodes in patients with squamous cell carcinoma of the penis

Exclusions:

  • All other indications

Pleural, thymus, heart and mediastinum cancer
Inclusions:

  • For surgical resection being considered and metastatic disease hasn’t been detected by CT or MRI
  • For restaging after induction chemotherapy, if the patient is a surgical candidate

Exclusions:

  • All other indications

Prostate cancer
Inclusions:

  • PET scanning with 11C-choline for evaluating response to primary treatment in prostate cancer

Exclusions:

  • PET scanning with 68Gallium in all aspects of managing prostate cancer
  • PET scanning for all other indications

Renal cell carcinoma
Inclusions:

  • For initial treatment strategy, subsequent treatment strategy and surveillance of biopsy proven kidney cancer

Exclusions:

  • Not applicable

Soft tissue sarcoma
Inclusions:

  • For initial staging prior to resection of an apparently solitary metastasis
  • When the grade of an unresectable tumor remains in doubt after biopsy
  • Differentiation of suspected tumor from radiation or surgical fibrosis
  • Determination of response to therapy, gastrointestinal stromal tumor for initial staging and re-staging when there is documented recurrence

Exclusions:

  • When used in evaluation of soft tissue sarcoma, including but not limited to the following applications:
    • Distinguishing between low-grade and high-grade soft tissue sarcoma
    • Detecting locoregional recurrence
    • Detecting distant metastasis

Testicular cancer
Inclusions:

  • PET canning in the evaluation of residual mass following chemotherapy of Stage IIB and III seminomas

Exclusions:
•     All other indications

Thyroid cancer
Inclusions:

  • For the initial treatment strategy of thyroid cancer types known not to concentrate radioactive iodine, or RAI
  • For subsequent treatment strategy for differentiated thyroid cancer of follicular cell origin, which is known to concentrate radioactive iodine, in all the following situations:
    • When done following prior treatment with thyroidectomy and radioiodine ablation
    • With a current serum thyroglobulin > 10 ng/ml (except in the setting of documented anti-thyroglobulin antibodies)
    • With a negative whole-body RAI scan in the past

Exclusions:

  • For the evaluation of known or suspected differentiated or poorly differentiated thyroid cancer in all other situations

Vaginal/vulvar cancers
Inclusions:

  • Radiation planning
  • Standard imaging studies are equivocal or nondiagnostic for recurrent or progressive disease
  • Restaging of local recurrence when pelvic exenteration surgery is planned

Exclusions:

  • All other indications

Cancer surveillance
Inclusions:

  • Not applicable

Exclusions:

When used as a surveillance tool for patients with cancer or with a history of cancer. A scan is considered surveillance if performed more than six months after completion of cancer therapy (12 months for lymphoma) in patients without objective signs or symptoms suggestive of cancer recurrence.

Established codes:
Genetic testing in patients at risk for FAP: 81201, 81202, 81203

Genetic testing in patients at risk for Lynch syndrome (HNPCC): 81210, 81288, 81292, 81293, 81294, 81295, 81296, 81297, 81298, 81299, 81300, 81301, 81317, 81318 81319, 81401, 81403, 81406, 81435, 81436

Note: 81401 and 81406 include MUTYH (e.g., MYH-associated polyposis)

Other codes (experimental, not medically necessary, etc.): 81327, 81528

Basic benefit and medical policy

Genetic Testing for Lynch Syndrome and Other Inherited Colon Cancer Syndromes policy

The safety and effectiveness of genetic testing for polyposis and non-polyposis cancer syndromes have been established. They may be considered useful diagnostic options for individuals who meet clinical criteria for increased risk of hereditary colorectal cancer. This policy is effective July 1, 2020.

Inclusions:

These guidelines refer to the different types of genetic tests available for colorectal cancer.

  1. Genetic testing of the adenomatous polyposis coli gene, or APC, is established in any of the following:
    • At-riska (first- and second-degree) relatives of patients with familial adenomatous polyposis, or FAP, or attenuated familial adenomatous polyposis, or AFAP, or a known APC variant
    • Patients with a differential diagnosis of attenuated FAP versus MUTYH-associated polyposis, or MAP, versus Lynch syndrome. Whether testing begins with APC variants or screening for mismatch repair MMR variants depends on clinical presentation.

aDue to the high lifetime risk of cancer of the majority of the genetic syndromes discussed in this policy, “at-risk relatives” primarily refers to first-degree (i.e., siblings, parents and offspring) and second-degree (i.e., grandparents, aunts, uncles, nieces, nephews, grandchildren and half-siblings) relatives. However, some judgment must be allowed; for example, in the case of a small family pedigree, when extended family members may need to be included in the testing strategy.

Note: It’s recommended that, when possible, initial genetic testing for familial adenomatous polyposis or Lynch syndrome be performed in an affected family member so that testing in unaffected family members can focus on the variant found in the affected family member.

  1. Genetic testing for MUTYH gene variants is established in all of the following:
    • Patients with a differential diagnosis of attenuated familial adenomatous polyposis versus MUTYH-associated polyposis versus Lynch syndrome
    • Negative result for APC gene variants
    • Negative family history of no parents or children with FAP is consistent with autosomal recessive MAP

Note: In many cases, genetic testing for MUTYH gene variants should first target the specific variants Y165C and G382D, which account for more than 80% of variants in white populations, and subsequently proceed to sequencing only as necessary. In other ethnic populations, however, proceeding directly to sequencing is appropriate.

  1. Genetic testing for MMR gene variants (MLH1, MSH2, MSH6, PMS2) to determine the carrier status of Lynch syndrome is established in any of the following:
    • Patients with colorectal cancer to test for the diagnosis of Lynch syndrome
    • Patients with endometrial cancer and one first-degree relative or ≥ two second-degree relatives diagnosed with a Lynch-associated cancer, for the diagnosis of Lynch syndrome
    • At-riska (first- and second-degree) relatives of patients with Lynch syndrome with a known MMR variant
    • Patients with a differential diagnosis of attenuated FAP versus MAP versus Lynch syndrome. Whether testing begins with APC variants or screening for MMR genes depends on clinical presentation
    • Patients without colorectal cancer but with a family history meeting the Amsterdam or Revised Bethesda criteria, or documentation of 5% or higher predicted risk of the syndrome on a validated risk prediction model (e.g., MMRpro, PREMM5 or MMRpredict) when no affected family members have been tested for MMR variants.

aDue to the high lifetime risk of cancer of the majority of the genetic syndromes discussed in this policy, “at-risk relatives” primarily refers to first-degree (i.e., siblings, parents and offspring) and second-degree (i.e., grandparents, aunts, uncles, nieces, nephews, grandchildren and half-siblings) relatives. However, some judgment must be allowed; for example, in the case of a small family pedigree, when extended family members may need to be included in the testing strategy.

Note: For patients with colorectal cancer being evaluated for Lynch syndrome, either the microsatellite instability, or MSI, test or the immunohistochemical, or IHC, test with or without BRAF gene variant testing, should be used as an initial evaluation of tumor tissue before mismatch repair MMR gene analysis. Both tests aren’t necessary. Proceeding to MMR gene sequencing would depend on results of MSI or IHC testing. In particular, IHC testing may help direct which MMR gene likely contains a variant, if any, and may also provide additional information if MMR genetic testing is inconclusive.

Note: When indicated, genetic sequencing for MMR gene variants should begin with MLH1 and MSH2 genes, unless otherwise directed by the results of IHC testing. Standard sequencing methods won’t detect large deletions or duplications; when MMR gene variants are expected based on IHC or MSI studies but none are found by standard sequencing, additional testing for large deletions or duplications is appropriate.

  1. Genetic testing for EPCAM gene variants is established when any of the following major criteria (solid bullets) is met:
    • Patients with colorectal cancer for the diagnosis of Lynch syndrome in one of the following:
      • Tumor tissue shows lack of MSH2 protein expression by immunohistochemistry and patient is negative for a MSH2 germline variant
      • Tumor tissue shows a high level of microsatellite instability and patient is negative for a germline variant in MSH2, MLH1, PMS2, and MSH6
    • At-riska (first- and second-degree) relatives of patients with Lynch syndrome with a known EPCAM variant
    • Patients without colorectal cancer but with a family history meeting the Amsterdam or Revised Bethesda criteria, or documentation of 5% or higher predicted risk of the syndrome on a validated risk prediction model (e.g., MMRpro, PREMM5 or MMRpredict) when both of the following are met:
      • No affected family members have been tested for MMR variants.
      • Sequencing for MMR variants is negative.

aDue to the high lifetime risk of cancer of the majority of the genetic syndromes discussed in this policy, “at-risk relatives” primarily refers to first-degree (i.e., siblings, parents and offspring) and second-degree (i.e., grandparents, aunts, uncles, nieces, nephews, grandchildren and half-siblings) relatives. However, some judgment must be allowed; for example, in the case of a small family pedigree, when extended family members may need to be included in the testing strategy.

The Amsterdam II Clinical Criteria (all criteria must be fulfilled) are the most stringent criteria for defining
families at high risk for Lynch syndrome (Vasen et al., 1999):

  • Three or more relatives with an associated cancer (colorectal cancer or cancer of the endometrium, small intestine, ureter or renal pelvis)
  • One should be a first-degree relative of the other two
  • Two or more successive generations affected
  • One or more relatives diagnosed before the age of 50
  • Familial adenomatous polyposis should be excluded in cases of colorectal carcinoma
  • Tumors should be verified by pathologic examination
  • Modifications, one of the following:
    • Very small families, which can’t be further expanded, can be considered to have hereditary nonpolyposis colorectal cancer, or  HNPCC, with only two colorectal cancers in first-degree relatives if at least two generations have the cancer and at least one case of colorectal cancer was diagnosed by the age of 55 years.
    • In families with two first-degree relatives affected by colorectal cancer, the presence of a third relative with an unusual early-onset neoplasm or endometrial cancer is sufficient.

The Revised Bethesda Guidelines (fulfillment of any criterion meets guidelines) are less strict than the Amsterdam criteria and are intended to increase the sensitivity of identifying at-risk families (Umar et al., 2004). The Bethesda guidelines are also considered more useful in identifying which patients with colorectal cancer should have their tumors tested for microsatellite instability and/or immunohistochemistry:

  • Colorectal carcinoma, or CRC, diagnosed in a patient who is less than 50 years old
  • Presence of synchronous or metachronous CRC or other HNPCC‒associated tumors,** regardless of age
  • CRC with high microsatellite instability histology diagnosed in a patient less than 60 years old
  • CRC diagnosed in one or more first-degree relatives with a Lynch syndrome-associated tumor, with one of the cancers being diagnosed at younger than 50 years of age
  • CRC diagnosed in two or more first- or second-degree relatives with HNPCC-related tumors,**  regardless of age.

 

**HNPCC-related tumors include colorectal, endometrial, stomach, ovarian, pancreas, ureter and renal pelvis, biliary tract, brain (usually glioblastoma as seen in Turcot syndrome), sebaceous bland adenomas and keratoacanthomas in Muir-Torre syndrome, and carcinoma of the small bowel.

  1. Genetic testing for BRAF V600E or MLH1 promoter methylation are established to exclude a diagnosis of Lynch syndrome when:
    • MLH1 protein isn’t expressed in a colorectal cancer tumor on immunohistochemical analysis.
  1. Genetic testing for SMAD4 and BMPR1A gene variants are established when any of the following major criteria (solid bullets) is met:
    • Individual has a clinical diagnosis of juvenile polyposis syndrome based on the presence of any one of the following:
      • At least three to five juvenile polyps in the colon
      • Multiple juvenile polyps in other parts of the gastrointestinal tract
      • Any number of juvenile polyps in a person with a known family history of juvenile polyps
    • Individual is an at-risk relative of a patient suspected of or diagnosed with juvenile polyposis syndrome.
  1. Genetic testing for STK11 gene variants is established when any of the following major criteria (solid bullets) is met:
    • Individual has a clinical diagnosis of Peutz-Jeghers syndrome based on the presence of any two of the following secondary criteria:
      • Presence of two or more histologically confirmed Peutz-Jeghers polyps of the small intestine
      • Characteristic mucocutaneous pigmentation of the mouth, lips, nose, eyes, genitalia or fingers
      • Family history of Peutz-Jeghers syndrome
    • Individual is an at-riska relative of a patient suspected of or diagnosed with Peutz-Jeghers syndrome.

aDue to the high lifetime risk of cancer of the majority of the genetic syndromes discussed in this policy, “at-risk relatives” primarily refers to first-degree (i.e., siblings, parents and offspring) and second-degree (i.e., grandparents, aunts, uncles, nieces, nephews, grandchildren and half-siblings) relatives. However, some judgment must be allowed; for example, in the case of a small family pedigree, when extended family members may need to be included in the testing strategy.

Pre- and post-test genetic counseling is established as an adjunct to genetic testing.

Note: Genetic counseling is primarily aimed at patients who are at risk for inherited disorders, and experts recommend formal genetic counseling in most cases when genetic testing for an inherited condition is considered. The interpretation of the results of genetic tests and the understanding of risk factors can be very difficult and complex. Therefore, genetic counseling will assist individuals in understanding the possible benefits and harms of genetic testing, including the possible impact of the information on the individual’s family. Genetic counseling may alter the utilization of genetic testing substantially and may reduce inappropriate testing. Genetic counseling should be performed by an individual with experience and expertise in genetic medicine and genetic testing methods.

Exclusions:

Genetic testing for APC gene variants is considered experimental for colorectal cancer patients with classical FAP for confirmation of the FAP diagnosis.

Genetic testing for all other gene variants for Lynch syndrome or colorectal cancer is considered experimental.

81519, 81520, 81521

Experimental:
S3854, 0045U, 81518, 81522,84999

Basic benefit and medical policy

Genetic tests for the prognosis of breast cancer

The safety and effectiveness of the use of the 21-gene reverse transcriptase-polymerase chain reaction (RT-PCR) assay (i.e., Oncotype DX®, the EndoPredict®, the Breast Cancer IndexSM, MammaPrint and Prosigna™ tests) to determine recurrence risk for deciding whether or not to undergo adjuvant chemotherapy have been established. They are useful diagnostic tests for determining the likelihood of distant cancer recurrence in women for patients who meet the inclusionary guidelines.

The use of the 21-gene reverse transcriptase-polymerase chain reaction assay (e.g., Oncotype DX, the EndoPredict®, the Breast Cancer IndexSM, MammaPrint and Prosigna™ tests, this is not an all-inclusive list) to determine hormonal therapy after five years is considered experimental.

Other genetic testing for determining the likelihood of distant cancer recurrence in women is experimental (refer to exclusions below).

This policy has been updated effective July 1, 2020.

Inclusions (must meet all):

The use of Oncotype Dx, the EndoPredict, the Breast Cancer Index, MammaPrint and Prosigna tests to determine recurrence risk for deciding whether or not to undergo adjuvant chemotherapy may be considered established in women with breast cancer meeting all of the following characteristics:

  • Unilateral tumor
  • Hormone receptor-positive (that is, estrogen-receptor [ER] positive or progesterone-receptor [PR]-positive)
  • Human epidermal growth factor receptor (HER) 2-negative
  • Tumor size 0.6-1 cm with moderate/poor differentiation or unfavorable features OR tumor size larger than 1 cm
  • Node negative (lymph nodes with micrometastases [less than 2 mm in size] are considered node negative for this policy).
  • Who will be treated with adjuvant endocrine therapy, i.e., tamoxifen or aromatase inhibitors
  • When the test result will aid the patient in making the decision regarding chemotherapy (i.e., when chemotherapy is a therapeutic option)
  • When ordered within six months after diagnosis, since the value of the test for making decisions regarding delayed chemotherapy is unknown. 

Or
Use of multigene assay to assess prognosis and determine chemotherapy benefit for node-positive, ER+, HER2- breast cancer with pN1mi (≤2 mm axillary node metastasis) or N1 (<4 nodes) is established.

These tests should only be ordered on a tissue specimen obtained during surgical removal of the tumor and after subsequent pathology examination of the tumor has been completed and determined to meet the above criteria (i.e., the test should not be ordered on a preliminary core biopsy). The test should be ordered in the context of a physician-patient discussion regarding risk preferences when the test result will aid in making decisions regarding chemotherapy.

For patients who otherwise meet the above characteristics but who have multiple ipsilateral primary tumors, a specimen from the tumor with the most aggressive histological characteristics should be submitted for testing. It isn’t necessary to conduct testing on each tumor; treatment is based on the most aggressive lesion.

Exclusions:

  • Gene expression assays when used in tandem with other similar assays is considered investigational, only a single assay should be used (i.e., Oncotype DX and MammaPrint should not be ordered on the same patient).
  • Use of a subset of genes from the 21-gene RT-PCR assay for predicting recurrence risk in patients with noninvasive ductal carcinoma in situ (DCIS) (i.e., Oncotype DX DCIS) to inform treatment planning following excisional surgery is considered experimental.
  • The use of other gene expression assays (e.g., Mammostrat® Breast Cancer Test, the BreastOncPx™, NexCourse® Breast IHC4, BreastPRS™, etc.) for any indication is experimental.
  • The use of gene expression assays in men with breast cancer is considered experimental.
  • The use of gene expression assays to molecularly subclassify breast cancer (e.g., BluePrint®) is considered experimental.
The use of gene expression assays for quantitative assessment of ER, PR and HER2 overexpression (e.g., TargetPrint®) is considered experimental.

95004, 95017, 95018, 95024, 95027, 95028, 95044, 95052, 95056, 95070, 95071, 95076, 95079, 95115, 95117, 95120, 95125, 95130, 95131, 95132, 95133, 95134, 95144, 95145, 95146, 95147, 95148, 95149, 95165, 95170, 95180, 82785, 86001, 86003, 86005, 86008

Experimental/not covered:
86343, 95060, 95065, 95199, 30999

Basic benefit and medical policy

Allergy testing and immunotherapy treatment

The safety and effectiveness of selected allergy testing and immunotherapy treatment of allergies have been established. They may be considered useful diagnostic and therapeutic options when indicated.

Inclusionary and exclusionary criteria have been updated, effective July 1, 2020. 

Inclusions:

  • Allergy testing:
    • Bronchial challenge tests
    • Direct skin test (percutaneous [scratch, prick or puncture] or intracutaneous [intradermal])
    • Double-blind food challenge test
    • Patch test (application test)
    • Photo patch test
    • In vitro IgE antibody tests (RAST, MAST, FAST, ELISA, ImmunoCAP)
    • Total serum IgE concentration
    • Serial (skin) endpoint titration (S.E.T. also known as the Rinkel test) when there is a high likelihood for a severe allergic reaction to specific agents such as antibiotics, nuts or other high-risk allergens
  • Immunotherapy treatments:
    • Appropriate in patients with demonstrated allergic hypersensitivity that can’t be managed by medications or avoidance
    • Oral immunotherapy with Palforzia™, when Pharmacy and Therapeutics policy criteria are met

Exclusions:

  • Allergy testing (this list may not be all-inclusive)
    • Antigen leukocyte cellular antibody, or ALCAT, automated food allergy testing (see policy titled “Antigen Leukocyte Antibody Test”)
    • Applied kinesiology or Nambudripad’s allergy elimination test (NAET; i.e., muscle strength testing or measurement after allergen ingestion)
    • Anti-Fc Epsilon receptor antibodies testing
    • Anti-IgE receptor antibody testing
    • Blood, urine or stool micro-nutrient assessments
    • Candidiasis test
    • Chemical analysis of body tissues (e.g., hair)
    • Chlorinated pesticides (serum)
    • Clifford materials reactivity testing
    • Complement (total or components)
    • Complement antigen testing (Sage)
    • C-reactive protein
    • Cytokine and cytokine receptor assay
    • Cytotoxic food, environmental or clinical ecological tests (Bryan’s test, ACT)
    • Direct mucous membrane test (conjunctival/ophthalmic, nasal)
    • Electrodermal testing or electro-acupuncture
    • Electromagnetic sensitivity syndrome/disorder (allergy to electricity, electro-sensitivity, electro-hypersensitivity and hypersensitivity to electricity)
    • Environmental cultures and chemicals
    • Eosinophil cationic protein, or ECP, test
    • Food immune complex assay, or FICA, or food allergenic extract immunotherapy
    • General immune system assessments
    • Immune complex assay
    • Iridology
    • Leukocyte antibodies testing
    • Leukocyte histamine release test, or LHRT/basophil histamine release test
    • Live cell analysis
    • Lymphocytes (B or T subsets)
    • Lymphocyte function assay
    • Mediator release test or the LEAP program
    • Metabolic assessments
    • Multiple chemical sensitivity syndrome (a.k.a., idiopathic environmental intolerance, clinical ecological illness, clinical ecology, environmental illness, chemical AIDS, environmental/chemical hypersensitivity disease, total allergy syndrome, cerebral allergy, 20th century disease)
    • Nasal challenge test
    • Prausnitz-Kustner or P-K testing/passive cutaneous transfer test
    • Provocation tests for food or food additive allergies
    • Pulse response test
    • Qualification of nutritional assessments
    • Rebuck skin window test
    • Secretory IgA (saliva, and other mucous secretions)
    • Allergen specific IgG (RAST/ELISA) testing
    • Sublingual provocative neutralization testing and treatment with hormones
    • Venom blocking antibodies
    • Volatile chemical panels (blood testing for chemicals)
  • Immunotherapy:
    • Oral immunotherapy**
    • Oral mucosal immunotherapy, including compounded toothpaste
    • Provocation and neutralization therapy for food allergies, using intradermal and subcutaneous routes
    • Rinkel injection therapy, also known as serial dilution endpoint titration therapy, for ragweed pollen hay fever
    • Enzyme-potentiated desensitization
    • Repository emulsion therapy
    • Urine auto injections (autogenous urine immunization)
    • Rhinophototherapy

**Exception: Palforzia™, when Pharmacy and Therapeutics Policy criteria are met

95803

Basic benefit and medical policy

Actigraphy

The medical policy statement has been updated for the Actigraphy medical policy. This policy is effective July 1, 2020.

Medical policy statement

Actigraphy is considered experimental when used as the sole technique to record and analyze body movement including, but not limited to, its use in the evaluation of sleep disorders. There is insufficient scientific evidence in the current medical literature to indicate that this technology is as beneficial as the established alternatives.

Note: When used as a component of portable sleep monitoring, actigraphy should not be reported separately.

Established
97151, 97152, 97153, 97154, 97155,**
97156,*** 97157,*** 97158, H0031, H0032
H2014, H2019, S5108, S5111,*** 0362T, 0373T

**Program modification of ABA therapy may be used as a combination of face-to-face and telemedicine services up to 50% of the time – as long as a behavior technician is present face to face.

***Training/treatment guidance may be delivered via telemedicine.

Basic benefit and medical policy

Applied Behavior Analysis for Autism Spectrum Disorder policy

The criteria have been updated for the Applied Behavior Analysis for Autism Spectrum Disorder policy, effective July 1, 2020.

Medical policy statement

The effectiveness of applied behavior analysis in the treatment of autism spectrum disorder has been established. It may be a useful therapeutic option when inclusionary and certificate guidelines are met.

Refer to member’s certificate for benefit specific coverage guidelines.

Inclusions:

  • Full diagnostic criteria for autism spectrum disorder, as published in the most recent edition of the American Psychiatric Association’s “Diagnostic and Statistical Manual,” are met.
  • The maladaptive behavior must affect the child’s personal safety, the safety of others within the child’s environment or must significantly interfere with the child’s ability to function.
  • Services in Michigan must be provided or supervised by one of the following:
    • Clinician who is a licensed behavior analyst
    • Psychiatrist who has the appropriate training
    • Licensed psychologist who has the appropriate education, training and experience
    • Person who holds a license, certificate or registration that authorizes them to perform services included in applied behavior analysis
  • Services outside of Michigan must be provided by a clinician who meets their state requirements to provide ABA therapy.
    • There is a treatment plan that:
      • Is child centered
      • Defines target behaviors
      • Records objective measures of baseline levels and progress
      • Identifies and documents specific interventions and techniques
      • Documents transitional and discharge plans

Exclusions:

  • People who don’t meet the diagnostic criteria based on the most recent criteria by the American Psychiatric Association (i.e., most current version of the Diagnostic and Statistical Manual)
  • In Michigan, therapy delivered or supervised by clinicians who aren’t licensed behavior analysts or those who do not meet state requirements to provide ABA therapy
  • Outside of Michigan, therapy delivered or supervised by clinicians who don’t meet their state requirements to provide ABA therapy
  • Therapy for persons older than age 18
  • Therapy is excluded from telemedicine**

**Exceptions:

  • Parent, guardian or caregiver adaptive behavior treatment training may be performed as a telemedicine service.
  • Program modification of ABA therapy may be used as a combination of face-to-face and telemedicine services up to 50% of the time as long as a behavior technician is present face to face.
Note: Refer to the medical policy Telemedicine Services.

E0766, A4555, 95999

Not covered:
A9900, E1399, 77299

Basic benefit and medical policy

Effective tumor-treating fields therapy

The safety and effectiveness of tumor-treatment fields, known as TTF, therapy have been established. It’s a useful therapeutic option for patients meeting specific selection criteria.

The criteria have been updated, effective July 1, 2020. 

Inclusions:

Treatment of newly diagnosed, histologically confirmed supratentorial glioblastoma multiforme when the following criteria are met:

  • Adults (22 years and older) when one of the following apply:
    • Used as an adjunct therapy to standard treatments that include maximal debulking surgery and completion of radiation together with the chemotherapy drug temozolomide (TMZ)
    • Continued as maintenance therapy, after TMZ completion, in responsive tumors
    • Monotherapy as an alternative to standard medical therapy in the reoccurrence of histologically or radiologically confirmed supratentorial glioblastoma multiforme tumor

Exclusions:

Tumor treating field therapy with any of the following:

  • Combined with chemotherapy other than TMZ
  • As an adjunct to standard medical therapy (pemetrexed and platinum-based chemo-therapy) for patients with malignant pleural mesothelioma
  • When used for any indications other than those listed above

J2501

Basic benefit and medical policy

Zemplar

Effective Oct. 17, 2019, Zemplar, procedure code J2502, is payable for the new clarified FDA-approved indications.

Zemplar paricalcitol injection is a vitamin D analog. When used as indicated, for the prevention and treatment of secondary hyperparathyroidism in patients ages 5 and older with chronic kidney disease on dialysis.

J3490
J3590

Basic benefit and medical policy

Jynneos

Jynneos is a vaccine indicated for the prevention of smallpox and monkeypox disease in adults ages 18 and older determined to be at high risk for smallpox or monkeypox infection. Blue Cross Blue Shield of Michigan considers it an established treatment.

J3490
J3590

Basic benefit and medical policy

Scenesse

Scenesse is a melanocortin 1 receptor, or MC1-R, agonist. When used to treat a patient as indicated, to increase pain-free light exposure in adult patients with a history of phototoxic reactions from erythropoietic protoporphyria, or EPP, Blue Cross Blue Shield of Michigan considers it an established treatment.

J9312

Basic benefit and medical policy

Rituxan (rituximab)

Effective Sept. 27, 2019, Rituxan (rituximab) is payable for pediatric patients age 2 years and older for the following updated indication for granulomatosis with polyangiitis, or GPA, (Wegener’s granulomatosis) and microscopic polyangiitis, or MPA:

  • Granulomatosis with polyangiitis (Wegener’s Granulomatosis) and microscopic polyangiitis in adult and pediatric patients ages 2 years and older in combination with glucocorticoids.

Dosing:

The induction dose for pediatric patients with GPA and MPA in combination with glucocorticoids is 375 mg/m2 once weekly for four weeks. The follow-up dose for pediatric patients with GPA and MPA who have achieved disease control with induction treatment, in combination with glucocorticoids is two 250 mg/m2 intravenous infusions separated by two weeks, followed by a 250 mg/m2 intravenous infusion every six months thereafter based on clinical evaluation.

Pharmacy doesn’t require prior authorization of this drug.
EXPERIMENTAL PROCEDURES

22899**

**Unlisted code used to report device

Basic benefit and medical policy

Infuse/Mastergraft™ device

The use of a Infuse/Mastergraft™ posterolateral revision device is considered experimental. It hasn’t been scientifically demonstrated to be as safe and effective as conventional treatment. This policy is effective July 1, 2020. 

Professional

Reminder: We’ve postponed some pharmacy initiatives

As you may have read in a web-DENIS message in April, the effective dates for some pharmacy initiatives that we communicated about in The Record have been postponed due to our efforts to combat COVID-19.

The following are links to the original Record articles, published in March and April, containing effective dates that are no longer valid:

Once the new effective dates for these initiatives have been established, we’ll communicate them through The Record.


New webinar recordings of 2020 sessions now available

Provider Experience continues to offer training resources to help your clinical and administrative staff work more efficiently with Blue Cross Blue Shield of Michigan and Blue Care Network. We’ve added recordings and videos of the following webinars to the Learning Opportunities section of web-DENIS:

  • Blue Cross 201: Claims Appeals Overview
  • e-referral Upgrades
  • Hyaluronic Acid Knee Injections
  • Medical benefit drugs: Prior authorization and claim submission scenarios (E-Learning)

To access recordings of the provider training webinars we’ve delivered so far in 2020 through web-DENIS, follow these steps:

For Blue Cross

  1. Click on BCBSM Provider Publications and Resources.
  2. Click on Newsletters & Resources.
  3. Click on Provider Training under Popular Links.
  4. Find the webinar you want in the Featured Links section.
  5. For Medical benefit drugs, click on E-Learning under Quick Access.

For BCN

  1. Click on BCN Provider Publications and Resources.
  2. Click on Learning Opportunities under Other Resources.
  3. Click on the link you want under 2020 Provider Training Webinars.

As additional training webinars become available, we’ll let you know about them through web-DENIS or The Record.


2020 InterQual® criteria to be implemented Aug. 1

Blue Cross Blue Shield of Michigan and Blue Care Network will start using 2020 InterQual criteria on Aug. 1, 2020, to make utilization management determinations. There is InterQual criteria for behavioral health services, as well as non-behavioral health services. However, for Blue Cross commercial members, New Directions, an independent company that provides behavioral health services for most Blue Cross members, uses its own criteria for making determinations.

Non-behavioral health services
We’ll use updated criteria for all levels of care to make utilization management determinations for requests to authorize non-behavioral health services, subject to review, for the following members:

  • Blue Cross commercial
  • Medicare Plus BlueSM
  • BCN commercial
  • BCN AdvantageSM

When clinical information is requested for a medical or surgical admission or for other services, we require submission of the specific components of the medical record that validate that the request meets the criteria.

Blue Cross and BCN also use local rules — modifications of InterQual criteria — in making utilization management determinations. The 2020 local rules will also go into effect on Aug. 1, 2020.

You’ll be able to access the updated versions of the modifications (local rules), as applicable, for [Note to reviewers – updated criteria will be posted by June 26]:

  • Blue Cross — on the Authorization Requirements & Criteria page in the Blue Cross section of our ereferrals.bcbsm.com website. You’ll see links to the criteria in both Blue Cross’ PPO and the Medicare Plus Blue PPO sections of that page. You can also find the 2020 InterQual criteria by the end of July within Provider Secured Services. After you log in, click BCBSM Provider Publications and Resources. Click Newsletters & Resources, click Clinical Criteria & Resources and scroll down to the section titled BCBSM modifications to InterQual criteria.
  • BCN — on the Authorization Requirements & Criteria page in the BCN section of our ereferrals.bcbsm.com website. Look under the Referral and authorization information heading.

Refer to the table below for more specific information on which criteria are used in making determinations for various types of non-behavioral health authorization requests.

Criteria/version Application
InterQual acute — Adult and pediatrics
  • Inpatient admissions
  • Continued stay discharge readiness
InterQual level of care — Subacute and skilled nursing facility
  • Subacute and skilled nursing facility admissions
  • Continued stay discharge readiness
InterQual rehabilitation — Adult and pediatrics
  • Inpatient admissions
  • Continued stay and discharge readiness
InterQual level of care — Long-term acute care
  • Long-term acute care facility admissions
  • Continued stay discharge readiness
InterQual level of care — Home care Home care requests
InterQual imaging Imaging studies and X-rays
InterQual procedures — Adult and pediatrics Surgery and invasive procedures
Medicare coverage guidelines (as applicable) Services that require clinical review for medical necessity and benefit determinations
Blue Cross and BCN medical policies Services that require clinical review for medical necessity
BCN-developed local rules (applies to BCN commercial and BCN Advantage) Exceptions to the application of InterQual criteria that reflect BCN’s accepted practice standards

Note: The information in the table above applies to lines of business and members whose authorizations are managed by Blue Cross or BCN directly and not by an independent company that provides services to Blue Cross Blue Shield of Michigan.

Behavioral health services
BCN commercial, BCN AdvantageSM and Medicare Plus BlueSM will begin using the 2020 InterQual® criteria for behavioral health utilization management determinations on Aug. 1.

In addition, certain types of determinations will be based on modifications to InterQual criteria or on local rules or medical policies, as shown in the table below.

Line of business Modified 2020 InterQual criteria for: Local rules or medical policies for:
BCN commercial

BCN Advantage

Medicare Plus Blue
  • Substance use disorders: Partial hospital program and intensive outpatient program.
  • Mental health disorders: Partial hospital program and intensive outpatient program.
  • Residential mental health treatment (adult/geriatric and child/adolescent)
  • Autism spectrum disorder/applied behavior analysis (for BCN commercial only).
  • Neurofeedback for attention deficit disorder/attention deficit hyperactivity disorder
  • Transcranial magnetic stimulation
  • Telemedicine (telepsychiatry/teletherapy)
  • Substance use disorders: Partial hospital program and intensive outpatient program.
  • Mental health disorders: Partial hospital program and intensive outpatient program.
  • None

Links to the updated versions of the modified criteria, local rules and medical policies will be available on the Blue Cross Behavioral Health page and the BCN Behavioral Health page at ereferrals.bcbsm.com.

As noted earlier in this article, determinations for behavioral health services for Blue Cross commercial members are handled by New Directions, an independent company that provides behavioral health services for most Blue Cross members. New Directions uses its own Medical Necessity Criteria.


Reminder: Providers must submit authorization requests to TurningPoint for musculoskeletal surgical procedures for certain members

As we reported in the May issue  of The Record, you need to submit authorization requests for all surgical procedures related to musculoskeletal conditions to TurningPoint, starting June 1, for dates of service on or after July 1. (The original launch date of June 1 had moved to July 1 due to the COVID-19 pandemic.)

Some important reminders:

  • This is effective for BCN commercial, BCN AdvantageSM and Medicare Plus BlueSM members.
  • Facilities should have an authorization number before scheduling surgery. The ordering physician or provider office must secure the authorization and provide the authorization number to the facility.
  • For inpatient professional claims, make sure to include only the procedure codes authorized for musculoskeletal procedures on your claim.
  • TurningPoint began accepting submitted authorization requests on June 1.

We’ll continue to offer webinar training for providers and facilities. Use the links below to register for webinars:

Where to find more information
For more information about TurningPoint, see the ereferrals webpages for Blue Care Network and Blue Cross Blue Shield of Michigan.

You can find procedure codes for orthopedic and spinal procedures managed by TurningPoint on ereferrals.bcbsm.com. Here are the links:

You can also refer to the Frequently asked questions document on our ereferrals.bcbsm.com website.


Blue Cross, BCN add provider group that addresses OCD, phobias and anxiety disorders by telehealth to network

Blue Cross Blue Shield of Michigan and Blue Care Network recently added a new provider group, called NOCD, that uses telehealth to address obsessive-compulsive disorders, phobias and anxiety disorders.

This addition to our network allows our members greater access to the evidence-based treatment called exposure response prevention, or ERP, therapy, which is a sophisticated version of cognitive behavioral therapy.

CBT has been the first-line treatment for these disorders for many years. While CBT provides relief for many people, exposure response prevention therapy can be helpful when CBT isn’t effective.

Until now, we’ve had a small number of specialized providers that address OCD and phobias, but they’ve been largely focused around the Ann Arbor and Grand Rapids areas.

NOCD’s integrated treatment model pairs a network of master’s level licensed professionals with online adherence tools and a peer community. Professional staff includes licensed psychologists, counselors and social workers who are trained in using exposure response prevention therapy for OCD treatment.

NOCD provides:

  • OCD-specific clinical diagnostic assessments in a video-based session
  • Scheduled video-based teletherapy in all geographic locations
  • Electronic messaging between the member and his or her NOCD professional

Other therapeutic tools include:

  • Structured electronic-based exercises and tools to assist in the therapy process
  • Support during any OCD episode
  • The ability to view treatment data in a secure, centralized area
  • An online, monitored peer support community to provide nonprofessional support and find resources to manage OCD

NOCD will also facilitate psychiatric consultation with a member’s provider for treatment intervention and coordination of care.

During the COVID-19 crisis, Blue Cross and BCN have allowed the use of telehealth services for all our providers. Overall, we’ve seen a 70% increase in the utilization of this type of care. NOCD uses telepsychotherapy and telemedicine visits exclusively, so this doesn’t limit their services geographically.

NOCD maintains an ongoing team of subject matter experts and OCD leading advisers. This includes individuals from the University of California, Los Angeles OCD treatment program; Yale Medical School; University of Southern California Medical School; University of Pennsylvania; Harvard Medical School and the University of Illinois, Chicago.

The addition of this provider adds to our network capacity and provides more evidence-based interventions for our membership. To make an appointment or refer a member, contact NOCD at 312-766-6780 or visit nocd.com.**

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


Preauthorize CT exams of abdomen and pelvis separately

As part of Blue Cross Blue Shield of Michigan’s PPO Radiology Management Program, participating providers must contact AIM Specialty Health® for prior authorization of non-emergency, outpatient imaging procedures.

Recently, Blue Cross has become aware of facilities performing both a CT of the abdomen and a CT of the pelvis when only one of these exams has been deemed medically necessary by AIM. It’s important to note that these exams are separate and distinct, and represented by different CPT codes. If a concurrent performance of these exams requires clinical review for the combination code, the ordering physician or provider must have the exam reviewed for medical necessity. From a clinical perspective, the two exams can be differentiated as follows:

  • CT imaging of the abdomen covers sections obtained from the diaphragmatic dome through the iliac crests. This anatomy includes the liver, biliary tract, pancreas, spleen, ad renal glands, kidneys, proximal ureters, lymph nodes, stomach and portions of the intestinal tract.
  • CT imaging of the pelvis extends from the iliac crests through the pubic symphysis and incudes the distal ureters, urinary bladder, lymph nodes, portions of the intestinal tract, as well as the prostate gland and seminal vesicles in males and the uterus, tubal structures and ovaries in females.

In many cases, concurrent or combined CT imaging of both anatomic areas aren’t required. For example, further characterization of one or more space-occupying liver lesions with triple-phase CT imaging doesn’t require a pelvic CT. Short term follow-up of an abnormality located in either the abdomen or pelvis doesn’t need imaging of the other anatomic region. In these cases, repeat combined imaging of both areas subject the patient to unnecessary radiation and is considered an ineffective use of medical resources.

There are several clinical reasons to perform combined abdominal and pelvic CT imaging. For example, evaluation of obstructive uropathy or work-up of acute intestinal tract abnormalities, such as suspected appendicitis or diverticulitis, may require imaging of both areas. AIM's clinical guidelines list further indications for combined imaging under the section titled “CT of the Abdomen & Pelvis." In these cases, the ordering provider should request clinical appropriateness reviews for both exams.

If it’s discovered that a concurrent and combined CT is medically necessary after the initial request for one of the separate abdomen or pelvis CT modality was already approved through AIM, you should  contact AIM to void the original request and request a medically necessity review through AIM’s provider portal before  the retro review period expires.

The computed tomography angiography, or CTA, also has an individual and concurrent modality. The CTA abdomen and pelvis are distinct from each other and have different medical necessity criteria. If a concurrent CTA is required, the actual combined procedure code should be requested for medical necessity review.

Health care providers providing the imaging should validate the exams included in the clinical review from the ordering provider before rendering the service, either by calling AIM at 1-800-728-8008 or accessing information online through AIM's provider portal at AIMSpecialtyHealth.com.


Hygieia can help Blue Cross members with Type 2 diabetes manage glucose levels

If Blue Cross Blue Shield of Michigan commercial or Medicare Plus BlueSM members with Type 2 diabetes need help managing their glucose levels, you can refer them to Hygieia.

Hygieia’s d-Nav® Insulin Management Program helps members achieve and maintain healthy A1c levels through virtual visits, telephone follow-ups and supplies by mail. This is especially important for members who are trying to manage their diabetes during times of crisis when they can’t leave their homes.

Hygieia also:

  • Provides patients with handheld devices that translate glucose readings into personalized recommended insulin doses
  • Teaches patients how to use the devices
  • Has clinical specialists follow up with patients to offer encouragement, correct usage errors and triage as needed
  • Sends the member back to you, the referring provider, for any issues that aren’t directly related to insulin management
  • Gives you access to detailed data on each member you refer, which is accessible through a secure portal

To refer Blue Cross members to Hygieia:

  • Email the member’s information to appointments@hygieia.com or fax it to 734‑249‑9650. Hygieia will reach out to the member to schedule an appointment.
  • You or the member can call or text 734‑369‑9984 to request an appointment.

Learn more about Hygieia and the d-Nav program at hygieia.com.**

** Blue Cross Blue Shield of Michigan doesn’t own or control this website.


Starting July 1, 2020, Praluent and Repatha will no longer be designated as specialty drugs

Starting July 1, 2020, the PCSK9 inhibitor drugs Repatha® and Praluent® will no longer be designated as specialty drugs. This means members can fill prescriptions for these drugs at any retail pharmacy in our network. And, if their prescription drug benefit allows it, they can fill a 90-day supply.

Specialty drugs require special handling, administration or monitoring. Some can only be filled by a specialty pharmacy.


Quarterly update: Requirements changed for some commercial medical benefit drugs

Blue Cross Blue Shield of Michigan and Blue Care Network encourage proper utilization of high-cost medications that are covered under the medical benefit. As part of this effort, we maintain a comprehensive list of requirements for both Blue Cross and BCN commercial members.

During April, May and June 2020, the following medical drugs had authorization requirement updates, site-of-care updates or both for Blue Cross commercial (PPO only) members:

HCPCS code Brand name Generic name
J0896*** Reblozyl® luspatercept-aamt
J3590** Palforzia™ peanut (Arachis hypogaea) allergen powder-dnfp
C9061*** Tepezza™ teprotumumab-trbw
J0222 Onpattro® patisiran
J7170 Hemlibra® emicizumab-kxwh
C9053*** Adakveo® crizanlizumab-tmca
C9056*** Givlaari® givosiran
J0202 Lemtrada® alemtuzumab
J2323 Tysabri® natalizumab
C9063*** Vyepti™ eptinezumab-jjmr
Q5121*** Avsola™ infliximab-axxq

** Will become a unique code
***A unique code was assigned to this drug on July 1, 2020. Prior to July 1, this drug was assigned to a not-otherwise-classified, or NOC, code.

For a detailed list of requirements, see the Blue Cross and BCN utilization management medical drug list.

Additional notes
The authorization requirements apply only to groups that are currently participating in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. For PPO groups that don’t require members to participate in the programs, refer to the Specialty Pharmacy Prior Authorization Master Opt-in/out Group List. This list is available on the Blue Cross Drugs Covered Under the Medical Benefit page of the ereferrals.bcbsm.com website.

These changes don’t apply to Federal Employee Program® Service Benefit Plan members.

An authorization approval isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.


Prior authorization lists changing for Medicare Plus Blue, BCN and BCN Advantage members

We’re adding authorization requirements for four specialty drugs covered under the medical benefit for Medicare Plus BlueSM, BCN commercial and BCN AdvantageSM members. The drugs (listed below) will require authorization through AIM Specialty Health®.

For dates of service on or after July 24, 2020:

  • Trodelvy™ (sacituzumab govitecan-hziy; HCPCS codes J3490, J3590, J9999)
  • Jelmyto™ (mitomycin; HCPCS codes J3490, J3590, J9999)
  • Darzalex Faspro™ (daratumumab and hyaluronidase-fihj; HCPCS codes J3490, J3590, J9999)

For dates of service on or after Aug. 24, 2020:

  • Imlygic® (talimogene laherparepvec; HCPCS code J9325)

How to submit AIM authorization requests

To learn more about the AIM ProviderPortal, check out their Frequently Asked Questions page** and register for an account.**

More about the authorization requirements
Authorization isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.

For more information on requirements related to drugs covered under the medical benefit, see:

We’ll update these lists with the new drug information before the effective dates.

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


URMBT’s Health & Well-Being Call program expands to include virtual visits

As we announced in a June Record article, Blue Cross Blue Shield of Michigan is using Signify Health for the UAW Retiree Medical Benefits Trust, or URMBT, Health & Well-Being Call program.

Through the program, a licensed doctor or nurse practitioner calls eligible URMBT subscribers and spouses to discuss their health status and identify any gaps in care. Starting June 1, Signify Health will offer members a virtual visit to conduct the wellness assessment. A virtual visit consists of audio and video components through a computer, tablet or smartphone.

These meetings include checks on the member’s well-being, an opportunity for the member to ask medical questions, and allows the practitioner to share information and care resources available to the member.
 
Signify Health will contact you if they are scheduled to call or virtually contact a patient who identifies you as their primary care physician. Following the call, Signify Health will send you a copy of the completed health assessment with any recommendations it  made to your patient regarding their health and follow-up care.

The program is available to URMBT members who have one of our Medicare Advantage plans (either Medicare Plus BlueSM or BCN AdvantageSM), as well as newly retired URMBT members who have Blue Cross Blue Shield of Michigan’s Enhanced Care Plan, or ECP.


Update your Provider Authorization form when changes occur

Blue Cross Blue Shield of Michigan is dedicated to safeguarding the protected health information of our members. These safeguards include completion of a Trading Partner Agreement and Provider Authorization form as part of the electronic data interchange setup process. All EDI trading partners must complete a TPA and Provider Authorization form before they can exchange PHI with Blue Cross.

Terms of the TPA require you to notify Blue Cross of any changes in your trading partner information. If you switch service bureaus (clearinghouses), software vendors, billing services or the recipient for your 835 files, you must update your Provider Authorization form. Updating the form ensures information is routed to the appropriate destination. You don’t need to update the Provider Authorization form if your submitter and Trading Partner IDs don’t change. 

Keep the following in mind when changes occur. You should review your provider authorization information if you’ve:

  • Joined a new group practice
  • Left a group practice and now bill using your own NPI
  • Hired a new billing service
  • Started submitting claims through a clearinghouse or you’ve changed clearinghouses
  • Decided you no longer want to receive 835 remittance files
  • Selected a new destination for your 835s

You must update your Provider Authorization form if you’ll be sending claims using a different submitter ID or routing your 835s to a different unique receiver or Trading Partner ID. To make changes to your EDI setup, visit bcbsm.com/providers and follow these steps:

  • Click on Quick Links.
  • Click on Electronic Connectivity (EDI).
  • Click on How to use EDI to exchange information with us electronically.
  • Click on Update your Provider Authorization Form under EDI Agreements.

If you have any questions about EDI enrollment, contact the EDI Help Desk at 1-800-542-0945. For assistance with the TPA and Provider Authorization form, click on Download step-by-step instructions for completing the TPA (PDF).


FEP supports prenatal care, well-child visits

Early prenatal care and frequent well-child visits have a significant impact on the start of a healthy life for children. That’s why the Blue Cross and Blue Shield Federal Employee Program® offers benefits and incentives to encourage members to stay healthy.

Prenatal care

  • Prenatal care visits are a covered benefit for all FEP Service Benefit Plan members: Standard Option, Basic Option and FEP Blue Focus.
  • The Pregnancy Care Incentive Program is available to Standard and Basic Option members. The program encourages timely prenatal care by rewarding members with a Pregnancy Care Box when a signed medical record is received showing their first trimester visit.

The Pregnancy Care Box is also available to Standard and Basic Option members upon request. The box includes books, educational pamphlets, samples, coupons and clothing items for the baby. For more information, visit fepblue.org/maternity.

Breastfeeding support

All FEP Service Benefit Plan members have benefit coverage for breastfeeding education and individual coaching by a certified lactation consultant. These members can receive a free breast pump kit and milk storage bags from Caremark by calling 1-800-262-7890.

Well-child visits

Well-child visits are covered 100% for all FEP Service Benefit Plan members when seen by a Preferred provider.

Keeping track of immunizations and developmental milestones can be a lot for parents. The Centers for Disease Control and Prevention provides a helpful and simple chart on immunizations and developmental milestones for children from birth through 6 years old. Click here** to view and share with your patients.

Healthy Families program

Available to all FEP Service Benefit Plan members, the Healthy Families program provides activities and tools to teach children about weight management, nutrition, physical activity and personal well-being. Members can learn more about this program by visiting fepblue.org/wellness-resources-and-tools.

For more information on any of these incentives, benefits or support programs for FEP Service Benefit Plan members, visit fepblue.org or call Customer Service at 1-800-482-3600.

**Blue Cross Blue Shield of Michigan doesn’t own or control this website.

Facility

New webinar recordings of 2020 sessions now available

Provider Experience continues to offer training resources to help your clinical and administrative staff work more efficiently with Blue Cross Blue Shield of Michigan and Blue Care Network. We’ve added recordings and videos of the following webinars to the Learning Opportunities section of web-DENIS:

  • Blue Cross 201: Claims Appeals Overview
  • e-referral Upgrades
  • Hyaluronic Acid Knee Injections
  • Medical benefit drugs: Prior authorization and claim submission scenarios (E-Learning)

To access recordings of the provider training webinars we’ve delivered so far in 2020 through web-DENIS, follow these steps:

For Blue Cross

  1. Click on BCBSM Provider Publications and Resources.
  2. Click on Newsletters & Resources.
  3. Click on Provider Training under Popular Links.
  4. Find the webinar you want in the Featured Links section.
  5. For Medical benefit drugs, click on E-Learning under Quick Access.

For BCN

  1. Click on BCN Provider Publications and Resources.
  2. Click on Learning Opportunities under Other Resources.
  3. Click on the link you want under 2020 Provider Training Webinars.

As additional training webinars become available, we’ll let you know about them through web-DENIS or The Record.


2020 InterQual® criteria to be implemented Aug.

Blue Cross Blue Shield of Michigan and Blue Care Network will start using 2020 InterQual criteria on Aug. 1, 2020, to make utilization management determinations. There is InterQual criteria for behavioral health services, as well as non-behavioral health services. However, for Blue Cross commercial members, New Directions, an independent company that provides behavioral health services for most Blue Cross members, uses its own criteria for making determinations.

Non-behavioral health services
We’ll use updated criteria for all levels of care to make utilization management determinations for requests to authorize non-behavioral health services, subject to review, for the following members:

  • Blue Cross commercial
  • Medicare Plus BlueSM
  • BCN commercial
  • BCN AdvantageSM

When clinical information is requested for a medical or surgical admission or for other services, we require submission of the specific components of the medical record that validate that the request meets the criteria.

Blue Cross and BCN also use local rules — modifications of InterQual criteria — in making utilization management determinations. The 2020 local rules will also go into effect on Aug. 1, 2020.

You’ll be able to access the updated versions of the modifications (local rules), as applicable, for [Note to reviewers – updated criteria will be posted by June 26]:

  • Blue Cross — on the Authorization Requirements & Criteria page in the Blue Cross section of our ereferrals.bcbsm.com website. You’ll see links to the criteria in both Blue Cross’ PPO and the Medicare Plus Blue PPO sections of that page. You can also find the 2020 InterQual criteria by the end of July within Provider Secured Services. After you log in, click BCBSM Provider Publications and Resources. Click Newsletters & Resources, click Clinical Criteria & Resources and scroll down to the section titled BCBSM modifications to InterQual criteria.
  • BCN — on the Authorization Requirements & Criteria page in the BCN section of our ereferrals.bcbsm.com website. Look under the Referral and authorization information heading.

Refer to the table below for more specific information on which criteria are used in making determinations for various types of non-behavioral health authorization requests.

Criteria/version Application
InterQual acute — Adult and pediatrics
  • Inpatient admissions
  • Continued stay discharge readiness
InterQual level of care — Subacute and skilled nursing facility
  • Subacute and skilled nursing facility admissions
  • Continued stay discharge readiness
InterQual rehabilitation — Adult and pediatrics
  • Inpatient admissions
  • Continued stay and discharge readiness
InterQual level of care — Long-term acute care
  • Long-term acute care facility admissions
  • Continued stay discharge readiness
InterQual level of care — Home care Home care requests
InterQual imaging Imaging studies and X-rays
InterQual procedures — Adult and pediatrics Surgery and invasive procedures
Medicare coverage guidelines (as applicable) Services that require clinical review for medical necessity and benefit determinations
Blue Cross and BCN medical policies Services that require clinical review for medical necessity
BCN-developed local rules (applies to BCN commercial and BCN Advantage) Exceptions to the application of InterQual criteria that reflect BCN’s accepted practice standards

Note: The information in the table above applies to lines of business and members whose authorizations are managed by Blue Cross or BCN directly and not by an independent company that provides services to Blue Cross Blue Shield of Michigan.

Behavioral health services
BCN commercial, BCN AdvantageSM and Medicare Plus BlueSM will begin using the 2020 InterQual® criteria for behavioral health utilization management determinations on Aug. 1.

In addition, certain types of determinations will be based on modifications to InterQual criteria or on local rules or medical policies, as shown in the table below.

Line of business Modified 2020 InterQual criteria for: Local rules or medical policies for:
BCN commercial

BCN Advantage

Medicare Plus Blue
  • Substance use disorders: Partial hospital program and intensive outpatient program.
  • Mental health disorders: Partial hospital program and intensive outpatient program.
  • Residential mental health treatment (adult/geriatric and child/adolescent)
  • Autism spectrum disorder/applied behavior analysis (for BCN commercial only).
  • Neurofeedback for attention deficit disorder/attention deficit hyperactivity disorder
  • Transcranial magnetic stimulation
  • Telemedicine (telepsychiatry/teletherapy)
  • Substance use disorders: Partial hospital program and intensive outpatient program.
  • Mental health disorders: Partial hospital program and intensive outpatient program.
  • None

Links to the updated versions of the modified criteria, local rules and medical policies will be available on the Blue Cross Behavioral Health page and the BCN Behavioral Health page at ereferrals.bcbsm.com.

As noted earlier in this article, determinations for behavioral health services for Blue Cross commercial members are handled by New Directions, an independent company that provides behavioral health services for most Blue Cross members. New Directions uses its own Medical Necessity Criteria.


Reminder: Providers must submit authorization requests to TurningPoint for musculoskeletal surgical procedures for certain members

As we reported in the May issue  of The Record, you need to submit authorization requests for all surgical procedures related to musculoskeletal conditions to TurningPoint, starting June 1, for dates of service on or after July 1. (The original launch date of June 1 had moved to July 1 due to the COVID-19 pandemic.)

Some important reminders:

  • This is effective for BCN commercial, BCN AdvantageSM and Medicare Plus BlueSM members.
  • Facilities should have an authorization number before scheduling surgery. The ordering physician or provider office must secure the authorization and provide the authorization number to the facility.
  • For inpatient professional claims, make sure to include only the procedure codes authorized for musculoskeletal procedures on your claim.
  • TurningPoint began accepting submitted authorization requests on June 1.

We’ll continue to offer webinar training for providers and facilities. Use the links below to register for webinars:

Where to find more information
For more information about TurningPoint, see the ereferrals webpages for Blue Care Network and Blue Cross Blue Shield of Michigan.

You can find procedure codes for orthopedic and spinal procedures managed by TurningPoint on ereferrals.bcbsm.com. Here are the links:

You can also refer to the Frequently asked questions document on our ereferrals.bcbsm.com website.


Blue Cross, BCN add provider group that addresses OCD, phobias and anxiety disorders by telehealth to network

Blue Cross Blue Shield of Michigan and Blue Care Network recently added a new provider group, called NOCD, that uses telehealth to address obsessive-compulsive disorders, phobias and anxiety disorders.

This addition to our network allows our members greater access to the evidence-based treatment called exposure response prevention, or ERP, therapy, which is a sophisticated version of cognitive behavioral therapy.

CBT has been the first-line treatment for these disorders for many years. While CBT provides relief for many people, exposure response prevention therapy can be helpful when CBT isn’t effective.

Until now, we’ve had a small number of specialized providers that address OCD and phobias, but they’ve been largely focused around the Ann Arbor and Grand Rapids areas.

NOCD’s integrated treatment model pairs a network of master’s level licensed professionals with online adherence tools and a peer community. Professional staff includes licensed psychologists, counselors and social workers who are trained in using exposure response prevention therapy for OCD treatment.

NOCD provides:

  • OCD-specific clinical diagnostic assessments in a video-based session
  • Scheduled video-based teletherapy in all geographic locations
  • Electronic messaging between the member and his or her NOCD professional

Other therapeutic tools include:

  • Structured electronic-based exercises and tools to assist in the therapy process
  • Support during any OCD episode
  • The ability to view treatment data in a secure, centralized area
  • An online, monitored peer support community to provide nonprofessional support and find resources to manage OCD

NOCD will also facilitate psychiatric consultation with a member’s provider for treatment intervention and coordination of care.

During the COVID-19 crisis, Blue Cross and BCN have allowed the use of telehealth services for all our providers. Overall, we’ve seen a 70% increase in the utilization of this type of care. NOCD uses telepsychotherapy and telemedicine visits exclusively, so this doesn’t limit their services geographically.

NOCD maintains an ongoing team of subject matter experts and OCD leading advisers. This includes individuals from the University of California, Los Angeles OCD treatment program; Yale Medical School; University of Southern California Medical School; University of Pennsylvania; Harvard Medical School and the University of Illinois, Chicago.

The addition of this provider adds to our network capacity and provides more evidence-based interventions for our membership. To make an appointment or refer a member, contact NOCD at 312-766-6780 or visit nocd.com.**

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


Preauthorize CT exams of abdomen and pelvis separately

As part of Blue Cross Blue Shield of Michigan’s PPO Radiology Management Program, participating providers must contact AIM Specialty Health® for prior authorization of non-emergency, outpatient imaging procedures.

Recently, Blue Cross has become aware of facilities performing both a CT of the abdomen and a CT of the pelvis when only one of these exams has been deemed medically necessary by AIM. It’s important to note that these exams are separate and distinct, and represented by different CPT codes. If a concurrent performance of these exams requires clinical review for the combination code, the ordering physician or provider must have the exam reviewed for medical necessity. From a clinical perspective, the two exams can be differentiated as follows:

  • CT imaging of the abdomen covers sections obtained from the diaphragmatic dome through the iliac crests. This anatomy includes the liver, biliary tract, pancreas, spleen, ad renal glands, kidneys, proximal ureters, lymph nodes, stomach and portions of the intestinal tract.
  • CT imaging of the pelvis extends from the iliac crests through the pubic symphysis and incudes the distal ureters, urinary bladder, lymph nodes, portions of the intestinal tract, as well as the prostate gland and seminal vesicles in males and the uterus, tubal structures and ovaries in females.

In many cases, concurrent or combined CT imaging of both anatomic areas aren’t required. For example, further characterization of one or more space-occupying liver lesions with triple-phase CT imaging doesn’t require a pelvic CT. Short term follow-up of an abnormality located in either the abdomen or pelvis doesn’t need imaging of the other anatomic region. In these cases, repeat combined imaging of both areas subject the patient to unnecessary radiation and is considered an ineffective use of medical resources.

There are several clinical reasons to perform combined abdominal and pelvic CT imaging. For example, evaluation of obstructive uropathy or work-up of acute intestinal tract abnormalities, such as suspected appendicitis or diverticulitis, may require imaging of both areas. AIM's clinical guidelines list further indications for combined imaging under the section titled “CT of the Abdomen & Pelvis." In these cases, the ordering provider should request clinical appropriateness reviews for both exams.

If it’s discovered that a concurrent and combined CT is medically necessary after the initial request for one of the separate abdomen or pelvis CT modality was already approved through AIM, you should  contact AIM to void the original request and request a medically necessity review through AIM’s provider portal before  the retro review period expires.

The computed tomography angiography, or CTA, also has an individual and concurrent modality. The CTA abdomen and pelvis are distinct from each other and have different medical necessity criteria. If a concurrent CTA is required, the actual combined procedure code should be requested for medical necessity review.

Health care providers providing the imaging should validate the exams included in the clinical review from the ordering provider before rendering the service, either by calling AIM at 1-800-728-8008 or accessing information online through AIM's provider portal at AIMSpecialtyHealth.com.


Quarterly update: Requirements changed for some commercial medical benefit drugs

Blue Cross Blue Shield of Michigan and Blue Care Network encourage proper utilization of high-cost medications that are covered under the medical benefit. As part of this effort, we maintain a comprehensive list of requirements for both Blue Cross and BCN commercial members.

During April, May and June 2020, the following medical drugs had authorization requirement updates, site-of-care updates or both for Blue Cross commercial (PPO only) members:

HCPCS code Brand name Generic name
J0896*** Reblozyl® luspatercept-aamt
J3590** Palforzia™ peanut (Arachis hypogaea) allergen powder-dnfp
C9061*** Tepezza™ teprotumumab-trbw
J0222 Onpattro® patisiran
J7170 Hemlibra® emicizumab-kxwh
C9053*** Adakveo® crizanlizumab-tmca
C9056*** Givlaari® givosiran
J0202 Lemtrada® alemtuzumab
J2323 Tysabri® natalizumab
C9063*** Vyepti™ eptinezumab-jjmr
Q5121*** Avsola™ infliximab-axxq

** Will become a unique code
***A unique code was assigned to this drug on July 1, 2020. Prior to July 1, this drug was assigned to a not-otherwise-classified, or NOC, code.

For a detailed list of requirements, see the Blue Cross and BCN utilization management medical drug list.

Additional notes
The authorization requirements apply only to groups that are currently participating in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. For PPO groups that don’t require members to participate in the programs, refer to the Specialty Pharmacy Prior Authorization Master Opt-in/out Group List. This list is available on the Blue Cross Drugs Covered Under the Medical Benefit page of the ereferrals.bcbsm.com website.

These changes don’t apply to Federal Employee Program® Service Benefit Plan members.

An authorization approval isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.


Prior authorization lists changing for Medicare Plus Blue, BCN and BCN Advantage members

We’re adding authorization requirements for four specialty drugs covered under the medical benefit for Medicare Plus BlueSM, BCN commercial and BCN AdvantageSM members. The drugs (listed below) will require authorization through AIM Specialty Health®.

For dates of service on or after July 24, 2020:

  • Trodelvy™ (sacituzumab govitecan-hziy; HCPCS codes J3490, J3590, J9999)
  • Jelmyto™ (mitomycin; HCPCS codes J3490, J3590, J9999)
  • Darzalex Faspro™ (daratumumab and hyaluronidase-fihj; HCPCS codes J3490, J3590, J9999)

For dates of service on or after Aug. 24, 2020:

  • Imlygic® (talimogene laherparepvec; HCPCS code J9325)

How to submit AIM authorization requests

To learn more about the AIM ProviderPortal, check out their Frequently Asked Questions page** and register for an account.**

More about the authorization requirements
Authorization isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.

For more information on requirements related to drugs covered under the medical benefit, see:

We’ll update these lists with the new drug information before the effective dates.

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


Update your Provider Authorization form when changes occur

Blue Cross Blue Shield of Michigan is dedicated to safeguarding the protected health information of our members. These safeguards include completion of a Trading Partner Agreement and Provider Authorization form as part of the electronic data interchange setup process. All EDI trading partners must complete a TPA and Provider Authorization form before they can exchange PHI with Blue Cross.

Terms of the TPA require you to notify Blue Cross of any changes in your trading partner information. If you switch service bureaus (clearinghouses), software vendors, billing services or the recipient for your 835 files, you must update your Provider Authorization form. Updating the form ensures information is routed to the appropriate destination. You don’t need to update the Provider Authorization form if your submitter and Trading Partner IDs don’t change. 

Keep the following in mind when changes occur. You should review your provider authorization information if you’ve:

  • Joined a new group practice
  • Left a group practice and now bill using your own NPI
  • Hired a new billing service
  • Started submitting claims through a clearinghouse or you’ve changed clearinghouses
  • Decided you no longer want to receive 835 remittance files
  • Selected a new destination for your 835s

You must update your Provider Authorization form if you’ll be sending claims using a different submitter ID or routing your 835s to a different unique receiver or Trading Partner ID. To make changes to your EDI setup, visit bcbsm.com/providers and follow these steps:

  • Click on Quick Links.
  • Click on Electronic Connectivity (EDI).
  • Click on How to use EDI to exchange information with us electronically.
  • Click on Update your Provider Authorization Form under EDI Agreements.

If you have any questions about EDI enrollment, contact the EDI Help Desk at 1-800-542-0945. For assistance with the TPA and Provider Authorization form, click on Download step-by-step instructions for completing the TPA (PDF).

Pharmacy

Reminder: We’ve postponed some pharmacy initiatives

As you may have read in a web-DENIS message in April, the effective dates for some pharmacy initiatives that we communicated about in The Record have been postponed due to our efforts to combat COVID-19.

The following are links to the original Record articles, published in March and April, containing effective dates that are no longer valid:

Once the new effective dates for these initiatives have been established, we’ll communicate them through The Record.


Starting July 1, 2020, Praluent and Repatha will no longer be designated as specialty drugs

Starting July 1, 2020, the PCSK9 inhibitor drugs Repatha® and Praluent® will no longer be designated as specialty drugs. This means members can fill prescriptions for these drugs at any retail pharmacy in our network. And, if their prescription drug benefit allows it, they can fill a 90-day supply.

Specialty drugs require special handling, administration or monitoring. Some can only be filled by a specialty pharmacy.


Quarterly update: Requirements changed for some commercial medical benefit drugs

Blue Cross Blue Shield of Michigan and Blue Care Network encourage proper utilization of high-cost medications that are covered under the medical benefit. As part of this effort, we maintain a comprehensive list of requirements for both Blue Cross and BCN commercial members.

During April, May and June 2020, the following medical drugs had authorization requirement updates, site-of-care updates or both for Blue Cross commercial (PPO only) members:

HCPCS code Brand name Generic name
J0896*** Reblozyl® luspatercept-aamt
J3590** Palforzia™ peanut (Arachis hypogaea) allergen powder-dnfp
C9061*** Tepezza™ teprotumumab-trbw
J0222 Onpattro® patisiran
J7170 Hemlibra® emicizumab-kxwh
C9053*** Adakveo® crizanlizumab-tmca
C9056*** Givlaari® givosiran
J0202 Lemtrada® alemtuzumab
J2323 Tysabri® natalizumab
C9063*** Vyepti™ eptinezumab-jjmr
Q5121*** Avsola™ infliximab-axxq

** Will become a unique code
***A unique code was assigned to this drug on July 1, 2020. Prior to July 1, this drug was assigned to a not-otherwise-classified, or NOC, code.

For a detailed list of requirements, see the Blue Cross and BCN utilization management medical drug list.

Additional notes
The authorization requirements apply only to groups that are currently participating in the standard commercial Medical Drug Prior Authorization Program for drugs administered under the medical benefit. For PPO groups that don’t require members to participate in the programs, refer to the Specialty Pharmacy Prior Authorization Master Opt-in/out Group List. This list is available on the Blue Cross Drugs Covered Under the Medical Benefit page of the ereferrals.bcbsm.com website.

These changes don’t apply to Federal Employee Program® Service Benefit Plan members.

An authorization approval isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.


Prior authorization lists changing for Medicare Plus Blue, BCN and BCN Advantage members

We’re adding authorization requirements for four specialty drugs covered under the medical benefit for Medicare Plus BlueSM, BCN commercial and BCN AdvantageSM members. The drugs (listed below) will require authorization through AIM Specialty Health®.

For dates of service on or after July 24, 2020:

  • Trodelvy™ (sacituzumab govitecan-hziy; HCPCS codes J3490, J3590, J9999)
  • Jelmyto™ (mitomycin; HCPCS codes J3490, J3590, J9999)
  • Darzalex Faspro™ (daratumumab and hyaluronidase-fihj; HCPCS codes J3490, J3590, J9999)

For dates of service on or after Aug. 24, 2020:

  • Imlygic® (talimogene laherparepvec; HCPCS code J9325)

How to submit AIM authorization requests

To learn more about the AIM ProviderPortal, check out their Frequently Asked Questions page** and register for an account.**

More about the authorization requirements
Authorization isn’t a guarantee of payment. Health care providers need to verify eligibility and benefits for members.

For more information on requirements related to drugs covered under the medical benefit, see:

We’ll update these lists with the new drug information before the effective dates.

**Blue Cross Blue Shield of Michigan and Blue Care Network don’t own or control this website.


Blue Cross and BCN will cover Truvada for HIV PrEP, starting in July

Effective July 1, 2020, Blue Cross Blue Shield of Michigan and Blue Care Network will cover HIV medication Truvada® for pre-exposure prophylaxis with no cost share for most commercial members at high risk for HIV.

A generic version of Truvada is expected to be released in September 2020. At that time, only the generic version will be covered with no cost share. The cost for brand Truvada will depend on the member’s benefit.

Truvada and Descovy® are the only two drugs indicated for HIV PrEP. If a member is newly prescribed Descovy for PrEP on or after May 1, 2020, we won’t cover the prescription unless prior authorization criteria are met. In such situations, prescribers should submit a prior authorization request. Otherwise, the prescription claim won’t be covered at the pharmacy.

We’ll only approve a prior authorization for Descovy for PrEP if there is documentation of a creatinine clearance (CrCl) less than 60 mL/min or osteoporosis.

Truvada and Descovy both contain tenofovir and emtricitabine. Each tenofovir component is formulated as a pro-drug.

Differences in pro-drug formulation and subsequent half-life don’t affect efficacy but can influence side effect profiles. Descovy demonstrated non-inferiority to Truvada in the DISCOVER trial, which means both drugs are equally effective in preventing the transmission of HIV-1.

Both drugs are contraindicated as PrEP in patients with unknown or positive HIV status. Using Descovy or Truvada for PrEP without confirmation of negative HIV status may increase the risk of developing HIV-1 resistance substitutions.

For members using Descovy to treat HIV, their normal cost share will apply.

Which members can receive this at $0 cost share?
This medication will be covered at $0 cost share for Blue Cross and BCN commercial members who are at high risk of contracting HIV. We’ll cover generic Truvada for PrEP at $0 cost share when it’s available. 
This change doesn’t apply to grandfathered employees, retirees or groups with religious accommodation exceptions.

Why are we doing this?
The U.S. Preventive Services Task Force has recommended that:

  • Providers offer PrEP with effective antiretroviral therapy to patients at high risk for HIV.
  • It must be offered with no cost share.

The Centers for Disease Control and Prevention reports that PrEP is highly effective for preventing HIV. Studies have shown that it reduces the risk of contracting HIV through sexual transmission by about 99% when taken daily. Among people who inject drugs, PrEP reduces the risk of getting HIV by at least 74% when taken daily. PrEP is much less effective if it isn’t taken consistently.

What is the USPSTF recommendation?
The following is the draft recommendation summary:

Population Recommendation Grade
People at high risk of HIV acquisition The USPSTF recommends that clinicians offer pre-exposure prophylaxis with effective antiretroviral therapy to people who are at high risk of HIV acquisition. A

A grade of A or B means it must be offered as preventive at $0 cost share.

Who can prescribe PrEP?
Any licensed prescriber can prescribe PrEP. Specialization in infectious diseases or HIV medicine isn’t required. In fact, primary care providers who routinely see people at risk for HIV acquisition should consider offering PrEP to all eligible members.

No portion of this publication may be copied without the express written permission of Blue Cross Blue Shield of Michigan, except that BCBSM participating health care providers may make copies for their personal use. In no event may any portion of this publication be copied or reprinted and used for commercial purposes by any party other than BCBSM.

*CPT codes, descriptions and two-digit numeric modifiers only are copyright 2019 American Medical Association. All rights reserved.