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July 2018

Facility

Beginning in July, PPO inpatient admission requests submitted through e-referral could be subject to clinical review

Starting July 9, 2018, inpatient acute care admissions for Blue Cross Blue Shield of Michigan commercial PPO members submitted through e-referral could be subject to clinical review. It’s a process that our facilities already follow for Medicare Advantage PPO inpatient acute care admissions and certain other members.

Clinical reviews like this become necessary as customers look for ways to reduce the amount they spend on medical services and as we try to consistently apply utilization management programs. For example, Blue Care Network, BCN AdvantageSM and Medicare Advantage PPO all have full inpatient review programs at Michigan hospitals.

These reviews also help us ensure that the patient stays are appropriate and billed correctly based on the patient’s diagnosis and condition.

With this inpatient review program, select facilities must submit medical inpatient stays through e-referral, and the requests could be reviewed and approved or pended for review by a clinician.

Additionally, behavioral health authorization requests and clinical reviews will continue according to the current process with the assigned behavioral health management vendor. However, inpatient admission authorization requests processed through New Directions** will be subject to full clinical review from the first day of admission and subject to non-approval. 

We’ve notified the affected facilities if their inpatient medical and behavioral health admissions require this new clinical review process.

If you’re not already familiar with e-referral or how the process works, contact your provider consultant for more information.

**New Directions is an independent company that provides behavioral health services for Blue Cross Blue Shield of Michigan.


We encourage you to join PGIP as a physician organization

We’re pleased to announce that we’ll accept applications for the Physician Group Incentive Program from new physician organizations from Aug. 1 through Aug. 31, 2018.

A PGIP physician organization consists of physicians working together to:

  • Transform systems of care to effectively manage patient populations.
  • Build the infrastructure needed to optimize, measure and monitor quality of care.

Physician organizations promote collaborative relationships and support the most cost-effective delivery of services to improve patient outcomes.

If you represent a physician organization and would like to join PGIP, send an email to valuepartnerships@bcbsm.com.

About PGIP
PGIP is an innovative provider program developed with input from doctors across Michigan to help improve the quality and efficiency of health care in the state. PGIP facilitates change through approximately 20 initiatives, including our nationally recognized Patient-Centered Medical Home program. It offers incentives for improving health care delivery to participating physicians, physician organizations and organized systems of care.

If you’re interested in participating in PGIP as an individual practitioner, click here. If you have questions about PGIP, contact your provider consultant. Not sure who that is? Visit the provider contacts page on our Blue Cross website. You’ll find more information in the middle of the page under the Provider consultants tab.

For more information
Visit these sites:


Reminder: Notify Medicare Plus Blue PPO members about their rights if post-acute care services will be terminated

As communicated in the June 2017 Record, post-acute care facility providers, whether contracted or non-contracted, must notify Medicare Plus BlueSM PPO members about their rights to appeal a decision regarding termination of post-acute care services.

They must do this by complying with the requirements for the delivery of a valid Notice of Medicare Non-Coverage (Centers for Medicare & Medicaid Services form 10123-NOMNC). This notice must be delivered to the member no later than two days before service termination.

Post-acute care facility providers include skilled nursing facilities, comprehensive outpatient rehabilitation facilities and home health agencies.

Upon receipt of a Notice of Medicare Non-Coverage, or NOMNC, members or their authorized representative have the right to an expedited appeal to a CMS-delegated quality improvement organization. In Michigan, KEPRO® is the delegated QIO.

When a member appeals

If the member or the authorized representative appeals to the QIO, the provider will receive an Expedited Appeal Documentation Request from the QIO. The provider must:

  • Deliver a valid Detailed Explanation of Non-Coverage to the member.
  • Respond to the QIO’s Expedited Appeal Documentation Request.
  • Submit supporting documentation within the time frame set by the QIO.

According to the Medicare Claims Processing Manual, Chapter 30, “If a Qualified Independent Contractor (QIO) determines that a provider did not deliver a valid NOMNC to a beneficiary, the provider is financially liable for continued services until two days after the beneficiary receives valid notice, or until the effective date of the valid notice, whichever is later.” Providers may not bill members for the balance of these services.

CMS forms and instructions
To access NOMNC and DENC forms and instructions, click here.**

**Blue Cross Blue Shield of Michigan doesn’t own or control this website.


Outpatient facilities added to Medicare Plus Blue prior authorization program

Beginning June 28, 2018, Blue Cross Blue Shield of Michigan expanded its prior authorization program for Medicare Plus BlueSM PPO specialty medical medications that are billed on a professional claim form to include outpatient facilities, place of service 19, 22 and 24. Currently, only place of service 11 is part of this program.

What you need to know

  • Select specialty medications are covered under the Medicare Part B medical benefit. The selected medications are not self-administered and must be administered (via injection or infusion) by a doctor or health care professional. In addition to current place of service 11, expansion to include outpatient facilities with place of service 19, 22 and 24 will begin June 28, 2018.
  • Place of service definitions:
    • 11 – Provider office
    • 19 – Off-campus outpatient hospital
    • 22 – On-campus outpatient hospital
    • 24 – Ambulatory surgical center
  • Prior authorization is required for professional claims submitted on an HCFA 1500 form or ANSI 837P electronic submission with place of service 11, 19, 22 and 24. Facility claims submitted using UB claim submission aren’t in scope for this expansion.
  • Providers must obtain prior authorization and verify patient benefits to be eligible for payment for administering these services. If a prior authorization isn’t obtained before services are rendered, the claim will be denied for no authorization on file. At that time, a provider may submit a retroactive authorization request within 90 days of the date of service. Patient must meet all requirements and have the necessary coverage for the claim to be payable.
  • Authorization isn’t a guarantee of payment. Benefits and eligibility must be determined at the time services are rendered.

Providers will submit Part B medical drug requests for dates of service electronically through NovoLogix®, a secure online tool, on or after June 28, 2018. NovoLogix allows providers to obtain real-time status checks on prior authorizations and to obtain immediate approvals for certain medications when patients meet the criteria. Submitting these requests electronically is the preferred method because it saves time and allows you to view the status of the request at any time. If your patient has an existing prior authorization for a provider-administered drug on file, an additional authorization for place of service 19, 22 or 24 isn’t required.

Future notifications will be sent that will provide you with the date when you can begin entering cases through the medical prior authorization e-tool if the patient doesn’t have an existing prior authorization on file with the provider’s office.

Look for more information about NovoLogix training and other program details in future issues of The Record and on web-DENIS.


Reminder: Update Provider Authorization Form when changes occur with your 835 ERA routing destination

Blue Cross Blue Shield of Michigan is dedicated to safeguarding the protected health information of our members. These safeguards include completion of a Trading Partner Agreement and Provider Authorization Form as part of the electronic data interchange setup process. All EDI trading partners must complete these forms to exchange PHI with Blue Cross.

Terms of the TPA require you to notify Blue Cross of any changes in your trading partner information. You must update your provider authorization information if you send claims using a different submitter ID or route your 835 electronic remittance advice to a different unique receiver or trading partner ID. Updating the form ensures information is routed to the appropriate destination.

Whenever you switch vendors, billing services or clearinghouses, you need to update your provider authorization. To make changes to your EDI setup, visit bcbsm.com/providers and follow these steps:

  • Click on Quick Links.
  • Click on Electronic Connectivity EDI.
  • Click on How to use EDI to exchange information with us electronically.
  • Click on Update your Provider Authorization Form.

Review your provider authorization information if you’ve:

  • Joined a new group practice
  • Left a group practice and now bill using your own NPI
  • Hired a new billing service
  • Started submitting claims through a clearinghouse or you’ve changed clearinghouses
  • Decided you no longer want to receive 835 files
  • Selected a new destination for your 835 files

If you have questions about EDI enrollment, contact our Help Desk at 1-800-542-0945. For assistance with the Trading Partner Agreement and Provider Authorization Form, select the TPA option.


Comply with semiannual request to update or confirm demographic data

Blue Cross Blue Shield of Michigan and Blue Care Network members rely on our online provider directory for correct, up-to-date information. Twice each year, the Provider Enrollment and Data Management team sends you the demographic information we have on file for you with a request to update or confirm it.

Facilities that don’t respond to this mailing won’t appear in our online directory.

Make it a priority to:

  • Respond to each request to update or confirm your demographic data.
  • Update your demographic data throughout the year as needed.

If you need to make changes to your data, send them Provider Enrollment and Data Management by mail, fax or email:

  • Mail: Provider Enrollment – Attestation
    20500 Civic Center Dr.
    Southfield, MI 48076-4115
    H200-PDA
  • Fax: 1-844-216-4941
    Email: providerdataintegrity@bcbsm.com

Need help making changes or have questions? You’ve got options:

  • Visit the Contact Us page of bcbsm.com/providers. (Scroll down to Update your information with us and select your provider type.)
  • Call Provider Enrollment at 1-800-822 2761.

Use modifier 96 for habilitative services

Health care providers must use modifier 96 to identify any physical therapy, occupational therapy or speech-language pathology codes for habilitative services. This allows us to track when habilitative (versus rehabilitative) services are reported.

On Jan. 1, 2018, modifier SZ was deleted and can no longer be used for tracking habilitative services. Modifier 96 replaces modifier SZ.


Professional

Improve HEDIS scores, reduce medical record requests through proper claims coding

Submitting claims with CPT® Category II and ICD-10 codes can help Blue Cross Blue Shield of Michigan determine if certain HEDIS® measures are met without needing to review medical records. This lessens the administrative burden on office staff because it reduces the need for them to pull medical records for Blue Cross’ review.

CPT II codes that support select HEDIS measures include:

HEDIS measure

CPT II code

Description

Medication reconciliation post discharge

*1111F

Discharge medications reconciled with the current medication list in outpatient medical record

Comprehensive diabetes care - eye exam
(The patient’s eye exam report must be included in your medical record).

*2022F

Dilated retinal eye exam with interpretation by an ophthalmologist or optometrist documented and reviewed

*3072F

Low risk for retinopathy (no evidence of retinopathy in the prior year)

Comprehensive diabetes care - HbA1c control

*3044F

Most recent HbA1c level < 7.0%

*3045F

Most recent HbA1c level 7.0-9.0%

*3046F

Most recent HbA1c level > 9.0%

Comprehensive diabetes care - medical attention for nephropathy

*3066F

Documentation of treatment for nephropathy (includes visit to nephrologist, receiving dialysis, treatment for end stage renal disease, chronic renal failure, acute renal failure or renal insufficiency)

*4010F

Angiotensin converting enzyme inhibitor or angiotensin receptor blocker therapy prescribed or currently being taken

Comprehensive diabetes care - blood pressure control

and

Controlling high blood pressure**

*3074F

Most recent systolic blood pressure <130 mm Hg

*3075F

Most recent systolic blood pressure 130 – 139 mm Hg

*3077F

Most recent systolic blood pressure > 140 mm Hg

*3078F

Most recent diastolic blood pressure <80 mm Hg

*3079F

Most recent diastolic blood pressure 80 – 89 mm Hg

*3080F

Most recent diastolic blood pressure > 90 mm Hg

**The National Committee for Quality Assurance requires medical record review for the controlling high blood pressure measure. However, for the comprehensive diabetes care – blood pressure control measure, CPT Category II codes can be used to identify compliant members through claims data when the member’s latest blood pressure reading is compliant (<140/90).

ICD-10 codes that support HEDIS exclusion criteria include:

Patients will not be identified for certain HEDIS measures when ICD-10 exclusion codes are submitted on a claim. These include:

Measure

ICD-10 code

Description

Breast cancer screening
Patients who have bilateral or two unilateral mastectomies

Z90.13

Acquired absence of bilateral breasts and nipples

Z90.12

Acquired absence of left breast and nipple

Z90.11

Acquired absence of right breast and nipple

Colorectal cancer screening
Patients who currently have or with a history of colorectal cancer. (Cancer of the small intestine doesn’t count.)

Z85.038

Personal history of other malignant neoplasm of large intestine

Z85.048

Personal history of other malignant neoplasm of rectum, rectosigmoid junction and anus

ICD-10 codes that support the adult BMI assessment measure include:

HEDIS measure

ICD-10 code

Description

Adult BMI

Z68.1

BMI of 19.99 or less

Z68.20

BMI 20.0-20.9

Z68.21

BMI 21.0-21.9

Z68.22

BMI 22.0-22.9

Z68.23

BMI 23.0-23.9

Z68.24

BMI 24.0-24.9

Z68.25

BMI 25.0-25.9

Z68.26

BMI 26.0-26.9

Z68.27

BMI 27.0-27.9

Z68.28

BMI 28.0-28.9

Z68.29

BMI 29.0-29.9

Z68.30

BMI 30.0-30.9

Z68.31

BMI 31.0-31.9

Z68.32

BMI 32.0-32.9

Z68.33

BMI 33.0-33.9

Z68.34

BMI 34.0-34.9

Z68.35

BMI 35.0-35.9

Z68.36

BMI 36.0-36.9

Z68.37

BMI 37.0-37.9

Z68.38

BMI 38.0-38.9

Z68.39

BMI 39.0-39.9

Z68.41

BMI 40.0-44.9

Z68.42

BMI 45.0-49.9

Z68.43

BMI 50.0-59.9

Z68.44

BMI 60.0-69.9

 

Z68.45

BMI 70.0 or greater

For more information on HEDIS measures, see our Clinical Quality Corner tip sheets. An article in this issue explains how to access them on web-DENIS.

HEDIS® is a registered trademark of the National Committee for Quality Assurance.


2018 Clinical Quality Corner tip sheets posted on web-DENIS

As you may have read in the May – June Hospital and Physician Update, we’ve updated our Clinical Quality Corner tip sheets for 2018.

The tip sheets are part of our ongoing efforts to give you the tools you need to improve health care quality. Each of the 27 tip sheets focuses on a specific HEDIS® measure.

This year, they’ve been posted on both the BCBSM Provider Publications and Resources section of web-DENIS, as well as on the BCN Provider Publications and Resources section. Here’s one way to access them:

From the homepage of web-DENIS:

  • Click on BCBSM Provider Publications and Resources.
  • Click on Newsletters & Resources.
  • Click on Clinical Quality Corner on the left side of the page.

HEDIS®, which stands for Healthcare Effectiveness Data and Information Set, is a registered trademark of the National Committee for Quality Assurance.


Talk with your patients about importance of complying with statin therapy

Several modifiable risk factors for cardiovascular disease are well-known and can be treated, including hyperlipidemia. Although treatments for hyperlipidemia, such as statin therapy, are effective and relatively inexpensive, many people aren’t controlling their condition adequately.

Talk with your patients about their risk factors associated with cardiovascular disease and the importance of complying with their statin treatment.

To read more about why statin therapy is beneficial for patients with cardiovascular disease, see the article in the July – August 2017 issue of Hospital and Physician Update, a Blue Cross Blue Shield of Michigan newsletter.

Did you know?
According to the Centers for Disease Control and Prevention:

  • Heart disease is the leading cause of death for men and women in the U.S.
  • An estimated one in every seven U.S. dollars spent on health care goes toward cardiovascular disease.
  • This expenditure totals more than $300 billion in annual health care costs and lost productivity from premature deaths each year.

Coding corner: Diabetic eye disease

Patients with diabetes require ongoing medical care and monitoring to reduce the risk of complications, such as diabetic retinopathy, and improve outcomes. Clinical interventions go far beyond glycemic control.

Diabetic retinopathy
Diabetic retinopathy is caused by persistent high blood sugar levels that, over time, cause damage to the blood vessels in the retina. The blood vessels can swell, leak or close, which impairs the blood supply to the retina. In advanced cases, abnormal new blood vessels can grow on the retina, a process known as neovascularization, which results in loss of vision.

What should primary care doctors do?
Ensure that your diabetic patients have an annual dilated eye screening exam for diabetic eye diseases to prevent or delay blindness. Also, obtain a copy of the eye exam report from the ophthalmologist or optometrist and include it in the patient’s medical record.

Stages of diabetic eye disease

  • Non-proliferative diabetic retinopathy: In this early stage, the blood vessels leak, making the retina swell and resulting in blurred vision
    • Swelling of the macula (the central part of the retina) is known as macular edema; it’s the most common reason for vision loss among diabetics.
    • Macular ischemia results when the blood supply to the macula is interrupted.
    • Stages of NPDR range from mild to severe, with or without macular edema.
  • Proliferative diabetic retinopathy: This advanced stage includes neovascularization, where the retina grows new abnormally fragile blood vessels, resulting in loss of vision.
    • These new blood vessels often bleed into the vitreous, causing floaters or varying degrees of vision loss.
    • The new blood vessels can also cause scar tissue to develop, resulting in problems with the macula and can lead to a detached retina.

Accurate documentation and coding
Health care providers should use the ICD-10-CM code Z13.5 (Encounter for screening for eye and ear disorders) until a definitive diagnosis has been determined by an eye care professional. Once definitively diagnosed, documentation and coding should be to the highest specificity of the disorder.

If primary care doctors receive no communication from the eye care professional but are aware of the presence of diabetic eye disease, they should document and code the condition to the highest specificity known to them. See the chart below for some examples.

Condition

ICD-10 code

Type 2 diabetes mellitus with unspecified diabetic retinopathy with macular edema

E11.311

Type 2 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema right eye

**E11.3211

Type 2 diabetes mellitus with severe nonproliferative diabetic retinopathy without macular edema left eye

**E11.3492

Type 2 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment involving the macula bilateral

**E11.3523

Type 2 diabetes mellitus with stable proliferative diabetic retinopathy unspecified eye

**E11.3559

Type 2 diabetes mellitus with diabetic cataract

E11.36

Type 2 diabetes mellitus with diabetic macular edema, resolved following treatment bilateral

**E11.37X3

**The seventh character is required for subcategories E11.32, E11.33, E11.34, E11.35 and E11.37 to designate laterality.

2018 updates to ICD-CM-10 Official Guidelines for Coding and Reporting

In Chapter 7, “Diseases of the Eye and Adnexa, Disorders of the Globe,” you’ll see a change to H42, Glaucoma in diseases classified elsewhere. The manual deletes the “excludes 2” note for glaucoma in diabetes mellitus and replaces it with an instructional note for appropriate sequencing that follows familiar coding conventions. The new note reads: “Code first glaucoma (in) diabetes mellitus (E08.39, E09.39, E10.39, E11.39, E13.39).”

None of the information included in this article is intended to be legal advice and, as such, it remains the provider’s responsibility to ensure that all coding and documentation are done in accordance with all applicable state and federal laws and regulations.


FEP provides pregnancy care incentives, promotes healthy lifestyles

The Blue Cross and Blue Shield Federal Employee Program® offers the Pregnancy Care Incentive Program to pregnant members and the Healthy Families programs for members with children.

The pregnancy care program encourages pregnant mothers to receive timely prenatal care and helps them make good choices to keep themselves and their babies healthy. It offers support and incentives during each stage of pregnancy. Eligible members can earn rewards toward a health account to be used for qualified expenses.

Once a child is born, FEP members can take advantage of the Healthy Families programs. These programs offer tools for developing healthy lifestyle habits from an early age, and address such topics as:

  • Vaccination schedules
  • Regular well-child visits
  • Weight management strategies
For more information, you can direct your patients to fepblue.org. There they can find details on both the Pregnancy Care Incentive Program and the Healthy Families programs under the Wellness Resources & Tools tab. Members can also call Customer Service at 1-800-482-3600.

We’ve made changes to Benefit Explainer

We’ve made changes to Benefit Explainer to make it easier for you to use.

On June 4, 2018, the Alerts — Form, General, Group and Topic — links and icons appeared in a larger, bold red typeface in the middle of the screen. This change affects the BPR, Medical/Payment Policy and Source Documents tabs in Benefit Explainer.

Below is an example of where the Alerts links and icons were located before the change in the BPR tab view.

1

Below is an example of where the Alerts links and icons are currently located in the BPR tab view.

2


Outpatient facilities added to Medicare Plus Blue prior authorization program

Beginning June 28, 2018, Blue Cross Blue Shield of Michigan expanded its prior authorization program for Medicare Plus BlueSM PPO specialty medical medications that are billed on a professional claim form to include outpatient facilities, place of service 19, 22 and 24. Currently, only place of service 11 is part of this program.

What you need to know

  • Select specialty medications are covered under the Medicare Part B medical benefit. The selected medications are not self-administered and must be administered (via injection or infusion) by a doctor or health care professional. In addition to current place of service 11, expansion to include outpatient facilities with place of service 19, 22 and 24 will begin June 28, 2018.
  • Place of service definitions:
    • 11 – Provider office
    • 19 – Off-campus outpatient hospital
    • 22 – On-campus outpatient hospital
    • 24 – Ambulatory surgical center
  • Prior authorization is required for professional claims submitted on an HCFA 1500 form or ANSI 837P electronic submission with place of service 11, 19, 22 and 24. Facility claims submitted using UB claim submission aren’t in scope for this expansion.
  • Providers must obtain prior authorization and verify patient benefits to be eligible for payment for administering these services. If a prior authorization isn’t obtained before services are rendered, the claim will be denied for no authorization on file. At that time, a provider may submit a retroactive authorization request within 90 days of the date of service. Patient must meet all requirements and have the necessary coverage for the claim to be payable.
  • Authorization isn’t a guarantee of payment. Benefits and eligibility must be determined at the time services are rendered.

Providers will submit Part B medical drug requests for dates of service electronically through NovoLogix®, a secure online tool, on or after June 28, 2018. NovoLogix allows providers to obtain real-time status checks on prior authorizations and to obtain immediate approvals for certain medications when patients meet the criteria. Submitting these requests electronically is the preferred method because it saves time and allows you to view the status of the request at any time. If your patient has an existing prior authorization for a provider-administered drug on file, an additional authorization for place of service 19, 22 or 24 isn’t required.

Future notifications will be sent that will provide you with the date when you can begin entering cases through the medical prior authorization e-tool if the patient doesn’t have an existing prior authorization on file with the provider’s office.

Look for more information about NovoLogix training and other program details in future issues of The Record and on web-DENIS.


Six additional drugs to be added to commercial PPO 15-day Specialty Drug Limitation Program, starting Aug. 1

Starting Aug. 1, 2018, the following six drugs are being added to the Blue Cross Blue Shield of Michigan commercial PPO 15-Day Specialty Drug Limitation Program:

  • Bosulif®
  • Caprelsa®
  • Exjade®
  • Erivedge®
  • Gilotrif®
  • Jadenu®

Instead of a 30-day supply, we’ll limit all fills to a 15-day supply. This includes first fills and refills. Members will pay half of their copayment for a 15-day supply.

Blue Cross limits the day-supply quantity of a medication that a pharmacy can dispense to:

  • Help save members money on copayments
  • Reduce drug waste

We’ll add more drugs to the 15-day program throughout the year. Here’s the full list, including the six new drugs:

Blue Cross commercial PPO
15-day Specialty Drug Limitation Program
Full drug list as of Aug. 1, 2018

Afinitor®

Bosulif®

Afinitor® Disperz

Cabometyx®

Calquence®

Caprelsa®

Cometriq®

Erivedge®

Exjade®

Gilotrif®

Imbruvicia® capsules

Lenvima®

Nexavar®

Nerlynx®

Tarceva®

Verzenio™

Votrient™

Zejula™

Zelboraf®

Zytiga™


Authorization for Fasenra™ and Luxturna™ required for Medicare Advantage members starting in August

As communicated in a May web-DENIS message, for dates of service on or after Aug. 7, 2018, authorization will be required for the following Part B specialty drugs covered under the medical benefit for Medicare Plus BlueSM PPO and BCN AdvantageSM members:

  • Fasenra (benralizumab)
  • Luxturna (voretigene neparvovec-rzyl)

Authorization for these drugs is already required for Blue Cross Blue Shield of Michigan and Blue Care Network commercial members.

For Medicare Plus Blue and BCN Advantage members, these medications require authorization when they are billed on a professional HCFA 1500 claim form or by electronic submission via ANSI 837P for these sites of care:

  • Physician office (place of service 11)
  • Outpatient facility (place of service 19, 22 and 24 for Medicare Plus Blue members and place of service 19 and 22 BCN Advantage members)

Authorization isn’t required for these medications when they are billed on a facility claim form, such as the UB-92, UB-04 or UCB.

You should bill both medications with procedure code J3590 and submit authorization requests for these medications through the NovoLogix online tool. Authorization must be obtained prior to administering the medications.


Commercial Medical Drug Prior Authorization Program adds Ilumya™

Starting Aug. 1, 2018, Ilumya (tildrakizumab-asmn) will be part of the Blue Cross Blue Shield of Michigan commercial Medical Drug Prior Authorization Program.

You can find information about the program by logging in to web-DENIS, clicking on BCBSM Provider Publications and Resources, and selecting Newsletters and Resources. Click Forms (under Other Resources), then Physician administered medications.

Keep in mind that the prior authorization requirement doesn’t apply to Federal Employee Program® members.

The list below reflects all the medications in the program as of Aug. 1:

Drug names

Actemra®

Elaprase®

Kalbitor®

Remicade®

Acthar® gel

Elelyso™           

Kanuma™

Ruconest®

Adagen®               

Entyvio™

Krystexxa®

Signifor® LAR

Aldurazyme®       

Exondys 51™

Lemtrada™

Simponi Aria®

Aralast NP™

Fabrazyme®

Lumizyme®

Soliris®

Aveed®

Fasenra™

Luxturna™

Spinraza™

Benlysta®

Firazyr®

Makena®

Stelara®

Berinert®

Flebogamma® DIF

Mepsevii™

Stelara IV®

Bivigam™

Gammagard Liquid®

Myobloc®

Synagis®

Botox®

Gammagard® S/D

Myozyme®          

Testopel®

Brineura™

Gammaked®

Naglazyme®    

Tysabri®

Carimune® NF

Gammaplex®

Nplate®

Vimizim™

Cerezyme®

Gamunex®

Nucala®

Vpriv®

Cimzia®

Glassia™

Ocrevus™

Xeomin®

Cinqair®

Hizentra®

Octagam®

Xgeva®

Cinryze®

HyQvia®

Orencia®

Xiaflex®

Cosentyx™

Ilaris®

Privigen®

Xolair®

Crysvita®

Ilumya™

Prolastin®-C

Yescarta®

Cuvitru®

Immune globulin

Prolia®

Zemaira®

Dysport®

Inflectra™

Radicava™

Zinplava™


Reminder: Update Provider Authorization Form when changes occur with your 835 ERA routing destination

Blue Cross Blue Shield of Michigan is dedicated to safeguarding the protected health information of our members. These safeguards include completion of a Trading Partner Agreement and Provider Authorization Form as part of the electronic data interchange setup process. All EDI trading partners must complete these forms to exchange PHI with Blue Cross.

Terms of the TPA require you to notify Blue Cross of any changes in your trading partner information. You must update your provider authorization information if you send claims using a different submitter ID or route your 835 electronic remittance advice to a different unique receiver or trading partner ID. Updating the form ensures information is routed to the appropriate destination.

Whenever you switch vendors, billing services or clearinghouses, you need to update your provider authorization. To make changes to your EDI setup, visit bcbsm.com/providers and follow these steps:

  • Click on Quick Links.
  • Click on Electronic Connectivity EDI.
  • Click on How to use EDI to exchange information with us electronically.
  • Click on Update your Provider Authorization Form.

Review your provider authorization information if you’ve:

  • Joined a new group practice
  • Left a group practice and now bill using your own NPI
  • Hired a new billing service
  • Started submitting claims through a clearinghouse or you’ve changed clearinghouses
  • Decided you no longer want to receive 835 files
  • Selected a new destination for your 835 files

If you have questions about EDI enrollment, contact our Help Desk at 1-800-542-0945. For assistance with the Trading Partner Agreement and Provider Authorization Form, select the TPA option.


Use modifier 96 for habilitative services

Health care providers must use modifier 96 to identify any physical therapy, occupational therapy or speech-language pathology codes for habilitative services. This allows us to track when habilitative (versus rehabilitative) services are reported.

On Jan. 1, 2018, modifier SZ was deleted and can no longer be used for tracking habilitative services. Modifier 96 replaces modifier SZ.


All Providers

Here’s an update on Blue Distinction Specialty Care

We wanted to remind you about this important Blue Cross and Blue Shield Association designation program and let you know how the program has changed over the past year.

About the program
Blue Distinction® Specialty Care recognizes health care facilities that demonstrate proven expertise in delivering high-quality, effective and cost-efficient care for select specialty areas. The program currently includes the following seven areas of specialty care:

  • Bariatric surgery
  • Cardiac care
  • Knee and hip replacement
  • Spine surgery
  • Maternity care
  • Cancer care
  • Transplants

The program includes two levels of designation:

Blue Distinction Centers are providers recognized for their expertise in delivering safe, effective, high-quality specialty care.

Blue Distinction Centers+ are providers recognized for their expertise and cost-efficiency in delivering specialty care. Only those providers that first meet Blue Distinction Centers’ nationally established, objective quality criteria are considered for designation as a Blue Distinction Center+.

Recent program changes

  • The complex and rare cancers program ended Dec. 31, 2017, and the new cancer care program launched Jan. 1, 2018. Here are features of the new program:
    • There’s no restriction on cancer type
    • Hospitals, physician groups and individual physicians can be designated.
    • The provider must be engaged in a value-based payment arrangement with a Blue plan to be designated.
    • There’s no BDC+ designation, only BDC.
  • As of Jan. 1, 2018, the bariatric surgery program went from a type of service designation (stapling versus banding) to a place-of-service designation (comprehensive center versus ambulatory surgery center). This means that an entity can either be designated for bariatric surgery as a comprehensive center or as an ASC.

Program refreshes

  • The Blue Cross and Blue Shield Association refreshes criteria for designation in each specialty area of the program about every two years to provide meaningful quality and cost differentiation to employers, employees and providers. To remain designated, facilities must reapply for Blue Distinction Center designations during each re-evaluation cycle.
  • The spine surgery and knee and hip replacement programs are being refreshed this year. In the new cycle, ASCs can earn BDC designation in addition to hospitals. This summer, Blue Cross Blue Shield of Michigan will be sending a letter to each facility that performs these procedures, inviting them to apply for designation by submitting a provider survey. The refreshed programs are tentatively scheduled to be effective July 1, 2019.

Coming next

  • A new fertility care program will launch Jan. 1, 2019.
  • A new gene therapy and cellular immunotherapy program is tentatively scheduled to launch Jan. 1, 2019.
  • A new substance use disorder program is tentatively scheduled to launch Jan. 1, 2020.

About selection criteria
Blue Distinction Center and Blue Distinction Center+ designations are awarded to facilities and providers based on a thorough, objective evaluation of their performance in the areas that matter most, including quality care, treatment expertise and overall patient results. Selection criteria are developed with the help of expert physicians and medical organizations. Blue Distinction Centers and Blue Distinction Centers+ have a proven history of delivering better quality and results, such as fewer complications and lower readmission rates, than those without these recognitions.

Finding a center
The Blue Distinction Specialty Care program provides broad national access to facilities and providers by delivering better quality specialty care, making them easy to find wherever you work and live across the U.S. You can easily locate a Blue Distinction Center at bcbs.com/blue-distinction-center-finder or by using our Find a Doctor feature at bcbsm.com.

Did you know?
Today, more than 3,600 Blue Distinction Center and Blue Distinction Center+ designations have been awarded to more than 1,900 health care facilities in 48 states.


Members who don’t meet criteria for covered services pay only the amount allowed by Blue Cross

When providers perform services that are covered under a member’s benefit plan but the coverage criteria isn’t met, the member is responsible for payment. However, the health care provider is obligated to accept the Blue Cross Blue Shield of Michigan allowed amount as payment in full.

This includes emergency department visits, ambulance services and non-cosmetic procedures. It doesn’t include services that aren’t covered under the benefit plan.

In addition, members are fully liable for any deductibles that haven’t been satisfied or if they failed to meet prior authorization requirements required by certain benefit plans. Again, their liability would be limited to the allowed amount for services that are covered under the benefit plan.

Our requirements for communicating the expected cost of services that aren’t part of the benefits under a plan haven’t changed.


Battling the opioid epidemic: A roundup of news and information

1 Campaign created to raise awareness of prescription drug abuse
Blue Cross Blue Shield of Michigan, the Michigan Health & Hospital Association, Michigan Osteopathic Association, the Michigan Open Prescribing Engagement Network and the Michigan State Medical Society recently teamed up to announce the “Be Rx SAFE” opioid awareness campaign. The campaign was created to raise awareness about the dangers of prescription drug abuse and overuse and encourage prescribers and patients to do their part in addressing the opioid crisis.

To learn more, read the MI Blues Perspective blog.

NIH doubles funding to develop scientific solutions to opioid crisis
At the 2018 National Rx Drug Abuse and Heroin Summit in April, the National Institutes of Health announced the launch of the Helping to End Addiction Long-term Initiative, or HEAL. As part of its effort to speed scientific solutions to stem the national opioid public health crisis, NIH is nearly doubling funding for research on opioid misuse, addiction and pain — from approximately $600 million in 2016 to $1.1 billion in 2018. The initiative has two main objectives: preventing addiction through enhanced pain management and improving treatments for opioid misuse disorder and addiction.

More information is available in the NIH news release.

New opioid treatment program tested for BCN members
A new clinical pilot program will test a comprehensive treatment model that Dr. William Beecroft, medical director for Blue Care Network, hopes will yield better results for members struggling with addiction. The program is called CLIMB, which stands for Community-based Life-changing Individualized Medically-assisted evidence-Based treatment program. It kicked off May 1 for 250 BCN and BCN AdvantageSM members. The 12-month pilot project will serve members at Pine Rest Christian Mental Health Services near Grand Rapids and at the Henry Ford Maplegrove Center in Bloomfield Hills.

Click here for more information.

Blue Cross, Walgreens team up to promote safe medication disposal
Blue Cross Blue Shield of Michigan and Walgreens have joined forces to make it easy and safe to dispose of unwanted medications with year-round medication disposal kiosks at 20 Walgreens pharmacies across the state. This is a convenient way to dispose of unused medications, including opioids and other controlled substances, and ensure they don’t fall into the wrong hands. The kiosks at select Walgreens pharmacies are available during regular pharmacy hours. The program began in 2016 and was recently expanded to include additional stores nationwide.

For more information and a list of the Walgreens kiosk locations in Michigan, see the May issue of Value Partnerships Update.

New online resource available to help curb opioid epidemic
Blue Cross Blue Shield of Michigan recently developed a website, mibluesperspectives.com/opioids101, to educate our members and the general public about the opioid epidemic, show what Blue Cross and its participating health care providers have done to tackle the problem, what we plan to do going forward and how the community can help. This easy-to-use website includes a wealth of resources that can be shared with patients and family members.


HCPCS update: New codes added

The Centers for Medicare & Medicaid Services has added several new codes as part of its quarterly Health Care Procedure Coding System updates. The codes, effective dates and Blue Cross Blue Shield of Michigan’s coverage decisions are below.

Medicine supplementary — Injections

Code

Change

Coverage comments

Effective date

Q9991

Added

Covered

July 1, 2018

Q9992

Added

Covered

July 1, 2018

Q9993

Added

Covered

July 1, 2018

Medicine supplementary — Durable medical equipment

Code

Change

Coverage comments

Effective date

Q9994

Added

Not covered

July 1, 2018

Medicine supplementary (anti-hemophilia drugs) — Injections

Code

Change

Coverage comments

Effective date

Q9995

Added

Covered

July 1, 2018

None of the information included in this article is intended to be legal advice and, as such, it remains the provider’s responsibility to ensure that all coding and documentation are done in accordance with all applicable state and federal laws and regulations.


Effective July 1, use new procedure code Q9995 for anti-hemophilia drug

The Center for Medicare & Medicaid Services has established a procedure code for emicizumab-kxwh, effective July 1, 2018.

When reporting injection services for this drug that were performed from Nov. 16, 2017, through June 30, 2018, continue to use code J7199. All injection services performed on or after July 1, 2018, must be reported with procedure code Q9995.

Emicizumab-kxwh continues to be covered for FDA-approved indications as established on Nov. 16, 2017. The U.S. Food and Drug Administration has approved this drug for use in preventing or reducing frequency of bleeding episodes in adults and pediatric patients who:

  • Have hemophilia A
  • Have developed antibodies called Factor VIII inhibitors via subcutaneous injection

This drug doesn’t require prior authorization from Blue Cross Blue Shield of Michigan.


Effective July 1, use new procedure code Q9993 when billing for Zilretta®

Effective July 1, 2018, the Center for Medicare & Medicaid Services has established a new procedure code for Zilretta, or triamcinolone acetonide.

All injection services for Zilretta from Oct. 9, 2017, through June 30, 2018, will continue to be reported with procedure code J3490. All injection services performed on or after July 1, 2018, must be reported with procedure code Q9993.

The National Drug Code for Zilretta is 70801-0003-01.

Zilretta continues to be covered for the FDA-approved indications as establisted on Oct. 9, 2017. The U.S. Food and Drug Administration approved Zilretta for the management of osteoarthritis pain of the knee.

This drug doesn’t require prior authorization from Blue Cross Blue Shield of Michigan.


Billing chart: Blues highlight medical, benefit policy changes

You’ll find the latest information about procedure codes and Blue Cross Blue Shield of Michigan billing guidelines in the following chart.

This billing chart is organized numerically by procedure code. Newly approved procedures will appear under the New Payable Procedures heading. Procedures for which we have changed a billing guideline or added a new payable group will appear under Updates to Payable Procedures. Procedures for which we are clarifying our guidelines will appear under Policy Clarifications. New procedures that are not covered will appear under Experimental Procedures.

You will also see that descriptions for the codes are no longer included. This is a result of recent negotiations with the AMA on use of the codes.

We will publish information about new BCBS groups or changes to group benefits under the Group Benefit Changes heading.

For more detailed descriptions of the BCBSM policies for these procedures, please check under the Medical/Payment Policy tab in Explainer on web-DENIS. To access this online information:

  • Log in to web-DENIS.
  • Click on BCBSM Provider Publications & Resources.
  • Click on Benefit Policy for a Code.
  • Click on Topic.
  • Under Topic Criteria, click on the drop-down arrow next to Choose Identifier Type and then click on HCPCS Code.
  • Enter the procedure code.
  • Click on Finish.
  • Click on Search.
Code* BCBSM changes to:
Basic Benefit and Medical Policy, Group
Variations Payment Policy, Guidelines
NEW PAYABLE PROCEDURES

81257, 81258, 81259, 81269

Basic benefit and medical policy

Genetic testing for alpha thalassemia

The safety and effectiveness of genetic testing for α-thalassemia for specified populations has been established. It may be considered a useful therapeutic option for patients who meet specific selection criteria, effective July 1, 2018.

Payment policy
Requires documentation for individual consideration.

Inclusions:
Preconception (carrier) testing for α-thalassemia in prospective parents may be considered established when the following are met:

  • Based on biochemical testing, one or both parents have evidence of one of the following:
    • A-thalassemia, including α-thalassemia minor or hemoglobin H disease (α-thalassemia intermedia)
    • A-thalassemia major

Exclusions:

  • Genetic testing to confirm a diagnosis of α-thalassemia
  • Genetic testing of patients with hemoglobin H disease (alpha-thalassemia intermedia) to determine prognosis
  • Genetic testing in other clinical situations

See policy guidelines below for more information.

Biochemical testing to determine whether α-thalassemia is present should be the first step in evaluating the presence of the condition. Biochemical testing consists of complete blood count, or CBC, microscopic examination of the peripheral blood smear, and hemoglobin electrophoresis. In silent carriers and in α-thalassemia trait, the hemoglobin electrophoresis will most likely be normal. However, there should be evidence of possible α-thalassemia minor on the CBC and peripheral smear.

The probability of a pregnancy with hemoglobin Bart’s (α-thalassemia major) is dependent on the specific genotype found in each parent. Table PG1 summarizes the risk according to each category of α-thalassemia.

 1

This policy doesn’t address prenatal (in utero or preimplantation) genetic testing for α-thalassemia.

Genetic testing for alpha thalassemia
Evidence indicates that confirmation of diagnosis in individuals who have suspected alpha-thalassemia can be verified based on biochemical testing without the need for genetic testing.

There is some evidence for a genotype-phenotype correlation with disease severity in individuals with hemoglobin H disease (alpha-thalassemia intermedia). However, there is no current evidence to indicate that patient management or outcomes would be altered. Therefore, the evidence is insufficient to determine the effects of the technology on health outcomes.

Preconception (carrier) testing is intended to avoid the most serious form of alpha-thalassemia, hemoglobin Bart’s. This condition leads to intrauterine death or death shortly after birth and is associated with increased obstetrical risks for the mother. Screening of populations at risk is first done by biochemical tests, including hemoglobin electrophoresis and complete blood count, along with peripheral smear. For individuals who are considering conception and have biochemical confirmation of alpha thalassemia, the evidence is sufficient to determine that genetic testing for alpha-thalassemia results in a meaningful improvement in the net health outcome.

90785, 90791, 90832, 90834, 90837, 90839, 90840, 90846,            90847, 90853, 90875, 90876, 90901, 96102, 96150, 96151, 96152, 96153, 96154

Basic benefit and medical policy

Modifiers HO and AJ

Starting June 1, 2018, when billing for behavioral health services supervised and rendered by limited or temporary limited license providers, please confirm that you’ve included an HO or AJ modifier on the claim.

This will properly identify the type of provider that rendered care to the patient and ensure accurate payment. Use the modifiers as follows:

HO
Limited license marriage and family therapist
Limited license professional counselor
Temporary limited license psychologist
Limited license psychologist

AJ
Limited license master social worker

Claims will be reimbursed at 80 percent of the Traditional Fee Schedule minus applicable member copay and/or deductible.

90785, 90791, 90832, 90834, 90837, 90839, 90840, 90846, 90847, 90853

Basic benefit and medical policy

Licensed marriage and family therapists

Beginning June 1, 2018, licensed marriage and family therapists are eligible to bill Blue Cross Blue Shield of Michigan and Blue Care Network for services within their scope of practice. The behavioral health procedures listed will be payable to licensed marriage and family therapists at 80 percent of the Traditional Fee Schedule.

90750

Basic benefit and medical policy

Shingrix (zoster vaccine recombinant, adjuvanted)

Effective Oct. 23, 2017, Shingrix (zoster vaccine recombinant, adjuvanted) is covered for the FDA-approved indications for the prevention of shingles. Shingrix (zoster vaccine recombinant, adjuvanted) should be reported with procedure code 90750. Pharmacy doesn’t require preauthorization of this drug. 

J3490

Basic benefit and medical policy

Cinvanti™ (aprepitant)

Effective Jan. 2, 2018, Cinvanti™ (aprepitant) is covered for the following Food and Drug Administration approved indications:

Cinvanti (aprepitant), an injectable emulsion for IV infusion, will be used to prevent chemotherapy-induced nausea and vomiting among adults. It must be used along with the other anti-emetic drugs, dexamethasone and a serotonin-3 (5-HT3) receptor inhibitor such as ondansetron. It can be administered to prevent chemotherapy-induced nausea and vomiting caused by chemo drugs that are either moderately or highly associated with chemotherapy-induced nausea and vomiting. Both acute and delayed episodes may be prevented, and Cinvanti can be used for first treatments as well as for subsequent rounds of chemo.

A substance P/neurokinin-1 (NK1) receptor antagonist, it works by blocking receptor sites in the brain. Doses are given as a 30-minute infusion about 30 minutes before the start of chemo on the first day. Recommended dosing is 130 milligrams for chemo that has a high risk of causing chemotherapy-induced nausea and vomiting and 100 milligrams for drugs with moderate risk. Packaged in single-dose 130mg vials, Cinvanti doesn’t contain polysorbate 80, an inactive ingredient that has caused infusion site reactions and hypersensitivity for some patients receiving products that include it.

Pharmacy doesn’t require preauthorization of this drug.

Note: This drug isn’t a benefit for URMBT.

J3490

Basic benefit and medical policy

Brineura (cerliponase alfa)

Effective April 27, 2017, Brineura (cerliponase alfa) is covered for the following FDA-approved indications:

Brineura is a hydrolytic lysosomal N-terminal tripeptidyl peptidase indicated to slow the loss of ambulation in symptomatic pediatric patients ages 3 and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase 1 (TPP1) deficiency. The recommended dosage is 300 milligrams administered once every other week as an intraventricular infusion followed by infusion of intraventricular electrolytes over approximately four-and-a-half hours.

The National Drug Code is 68135-0811-02.

J9999

Basic benefit and medical policy

FDA approves Lutathera

The Food and Drug Administration approved Lutathera as appropriate for use in the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs), including foregut, midgut and hindgut neuroendocrine tumors in adults, effective Jan. 26, 2018.

Lutathera will be reviewed for individual consideration.

URMBT is excluded.

UPDATES TO PAYABLE PROCEDURES

43644, 43645, 43770- 43775, 43842- 43848, 43886- 43888, 43999, 44130, 96101- 96103, S2083

Non-covered:
 43999**

** When used to indicate any of the following procedures:

  • Loop gastric bypass gastroplasty, also known as mini-gastric bypass
  • Stomach stapling
Endoscopic procedures to treat weight gain after bariatric surgery

Basic benefit and medical policy

Bariatric surgery

The safety and effectiveness of laparoscopic and open gastric restrictive procedures including, but not limited to, gastric-band, Roux-en-Y, gastric bypass, sleeve gastrectomy and biliopancreatic diversion have been established. They may be considered useful therapeutic options when specified criteria are met.

The exclusionary criteria have been updated, effective July 1, 2018.

Basic benefit policy group variations
Reference member benefits

Inclusions:
The surgical procedures for severe obesity, including sleeve gastrectomy, are considered established treatment options if all the following criteria are met:

  • The patient has a BMI >40 or a BMI of >35 with one or more co-morbid conditions including, but not limited to:
    • Degenerative joint disease (including degenerative disc disease)
    • Hypertension
    • Hyperlipidemia, coronary artery disease
    • Presence of other atherosclerotic diseases
    • Type II diabetes mellitus
    • Sleep apnea
    • Congestive heart failure 
  • Bariatric surgery may be indicated for patients ages 18 to 60. Requests for bariatric surgery for patients younger than 18 should include documentation that the primary care physician has addressed the risk of surgery on future growth, the patient's maturity level and the patient’s ability to understand the procedure and comply with postoperative instructions, as well as the adequacy of family support. Patients older than 60 may be considered if it’s documented in the medical record that the patient’s physiologic age and co-morbid conditions result in a positive risk/benefit ratio.
  • The patient has been clinically evaluated by an M.D. or D.O. (or their authorized delegate (e.g., physician assistant, etc.). The physician has documented failure of nonsurgical management including a structured, professionally supervised (physician or non-physician) weight loss program for a minimum of:
    • For Blue Cross Blue Shield of Michigan patients, six full, consecutive months (180 days) within the last four years prior to the recommendation for bariatric surgery.
    • For Blue Care Network patients, six full, consecutive months (180 days) within the last two years prior to the recommendation for bariatric surgery. 
    • The weight loss program listed above (six full, consecutive months, or 180 days) is waived for super morbidly obese individuals who have a BMI ≥50. Documentation should include periodic weights, dietary therapy and physical exercise, as well as behavioral therapy, counseling and pharmacotherapy, as indicated.
  • Documentation that the primary care doctor and the patient have a good understanding of the risks involved and reasonable expectations that the patient will be compliant with all post-surgical requirements.
  • A psychological evaluation must be performed as a pre-surgical assessment by a contracted mental health professional to establish the patient’s emotional stability, ability to comprehend the risk of surgery and to give informed consent, and ability to cope with expected post-surgical lifestyle changes and limitations.  Such psychological consultations may include one unit total of psychological testing for purposes of personality assessment (e.g., the MMPI-2 or adolescent version, the MMPI-A).
  • The physician needs to be aware and follow up with individuals who have had gastric surgery for any long-term complications.
  • In cases where a revision of the original procedure is planned because of failure due to anatomic or technical reasons (e.g., obstruction, staple dehiscence, etc.), or excessive weight loss of 20 percent or more below ideal body weight, the revision is determined to be medically appropriate without consideration of the initial preoperative criteria. The medical records should include documentation of:
    • The date and type of the previous procedure.
    • The factors that precipitated the failure or the nature of the complications from the previous procedure that mandate (necessitate) the takedown.
  • If the indication for the revision is a weight gain or a failure of the patient to lose a desired amount of weight due to patient nonadherence, then the patient must requalify for the subsequent procedure and meet all the initial preoperative criteria.

Exclusions:
The following surgical procedures are considered experimental because their safety or effectiveness have not been proven:

  • Gastric bypass using a Billroth II type of anastomosis, also known as mini gastric bypass
  • Biliopancreatic bypass without duodenal switch
  • Long-limb gastric bypass procedure (i.e., >150 cm).
  • Stomach stapling
  • Endoscopic/endoluminal procedures (including, but not limited to, insertion of the StomaphyX™ device, insertion of a gastric balloon, endoscopic gastroplasty or use of an endoscopically placed duodenojejunal sleeve) as a primary bariatric procedure or as a revision procedure, (i.e., to treat weight gain after bariatric surgery to remedy large gastric stoma or large gastric pouches)
  • Any bariatric surgery for patients with Type 2 diabetes who have a BMI of less than 35
  • Laparoscopic gastric plication
  • Vagus nerve blocking (see separate policy, “Vagus Nerve Blocking for Morbid Obesity”)
  • Single anastomosis duodenoileal bypass with sleeve gastrectomy, or ADI-S
  • Stomach intestine pylorus sparing surgery, or SIPS
  • Bariatric surgery for pre-adolescents
  • Intragastric balloons
  • Aspiration therapy device

81302, 81303, 81304, 81404, 81406

Basic benefit and medical policy

Genetic testing for Rett syndrome

The safety and effectiveness of genetic testing for Rett syndrome have been established. It may be considered a useful diagnostic option for select individuals.

Inclusionary criteria have been updated, effective July 1, 2018.

Inclusions:

  • When testing is performed to confirm a diagnosis of Rett syndrome in a female child with developmental delay and signs or symptoms of Rett syndrome, but when there is uncertainty in the clinical diagnosis (e.g., MECP2, FOXG1 or CDKL5).
  • Targeted genetic testing for a known familial Rett syndrome-associated variant to determine carrier status of a mother or a sister of an individual with Rett syndrome.

Exclusions:

  • All other indications for genetic testing for Rett syndrome-associated genes (e.g., MECP2, FOXG1 or CDKL5), including carrier testing (preconception or prenatal), and testing of asymptomatic family members to determine future risk of disease.

81324, 81325, 81326, 81403, 81404, 81405, 81406, 81448, 81479

Basic benefit and medical policy

Genetic testing for the diagnosis of inherited peripheral neuropathies

The safety and effectiveness of genetic testing for inherited peripheral neuropathies have been established. It may be considered a useful diagnostic option for patients meeting the specified selection criteria.

Inclusionary and exclusionary criteria have been updated, effective July 1, 2018.

Inclusions:
Genetic testing for an inherited peripheral neuropathy is considered established when:

  • The diagnosis of an inherited peripheral motor or sensory neuropathy is suspected due to clinical signs and symptoms but a definitive diagnosis can’t be made.

Exclusions:

  • Genetic testing for an inherited peripheral neuropathy is excluded for all other indications.

J3490

Basic benefit and medical policy

Giapreza (angiotensin II)

Giapreza (angiotensin II) is a vasoconstrictor to increase blood pressure in adults with septic or other distributive shock. It’s administered intravenously at 20 nanograms (ng)/kg/min. Titrate as frequently as every five minutes by increments of up to 15 ng/kg/min as needed. During the first three hours, the maximum dose should not exceed 80 ng/kg/min. Maintenance dose should not exceed 40 ng/kg/min.

URMBT groups are excluded from this change.

POLICY CLARIFICATIONS

19294

Basic benefit and medical policy

Accelerated breast irradiation after breast-conserving surgery for early stage breast cancer and breast brachytherapy as boost with whole-breast irradiation

Following breast-conserving surgery for early stage breast cancer:

  • Accelerated whole breast irradiation and interstitial or balloon brachytherapy may be considered established for patients who meet inclusionary guidelines. These procedures are useful therapeutic options for patients meeting selection criteria.
  • Accelerated whole breast irradiation is considered experimental in all other situations involving treatment of early stage breast cancer after breast-conserving surgery.
  • Interstitial or balloon brachytherapy may be considered established for patients undergoing initial treatment for stage I or II breast cancer when used as local boost irradiation in those who are also treated with breast-conserving surgery and whole-breast external-beam radiotherapy.
  • Accelerated partial breast irradiation and intra-operative APBI are established when meeting ASTRO guidelines.
  • Noninvasive brachytherapy using Accuboost® for patients undergoing initial treatment for stage 1 or 2 breast cancer when used as local boost irradiation in patients who are also treated with breast-conserving surgery and whole breast external-beam radiotherapy is considered experimental.

Local boost irradiation when combined with whole-breast radiotherapy but without surgical excision is considered experimental. There is a lack of published data to validate the efficacy of brachytherapy without surgical excision of the tumor. This policy is effective May 1, 2018.

Inclusions:
Following breast-conserving surgery for early stage breast cancer:

  • Accelerated whole breast irradiation may be considered appropriate for both 1 and 2 stages of breast cancer. 
  • Accelerated partial breast irradiation may be considered appropriate when all of the following criteria are met:
    • Age 45 or older for invasive breast cancer and older than age 50 for DCIS
    • Tumor less than or equal to three centimeters with pathologically negative surgical margins
    • Lymph nodes are negative show only immune histochemical involvement.
  • Intraoperative radiation therapy is appropriate when all the following criteria are met:
    • Age 50 or older
    • Tumor equal to or less than three centimeters with grossly uninvolved surgical margins
    • Lymph nodes are grossly negative and negative on intraoperative frozen section if performed.
  • Interstitial or balloon brachytherapy may be considered established for patients undergoing initial treatment for stage 1 or 2 breast cancer when used as local boost irradiation in patients who are also treated with breast-conserving surgery and whole-breast external-beam radiotherapy.

Exclusions:

  • Accelerated whole breast irradiation for patients not meeting the above inclusions
  • Interstitial or balloon brachytherapy in all other situations not specified under the inclusions
  • Noninvasive brachytherapy using Accuboost® for patients undergoing initial treatment for stage 1 or 2 breast cancer when used as local boost irradiation in patients who are also treated with breast-conserving surgery and whole breast external-beam radiotherapy
  • Local boost irradiation when combined with whole-breast radiotherapy but without surgical excision

27415, 27416, 28446, 29866, 29867

Noncovered:
29999**, 27899**

**Unlisted procedures for arthroscopy
 or leg and ankle

Basic benefit and medical policy

Autografts and allografts in the treatment of focal articular cartilage lesions

The safety and effectiveness of osteochondral allografting and autografting for defects of the knee joint and talus bone have been established. It’s a useful therapeutic option for patients meeting specific patient selection criteria.

Osteochondral allografting
The safety and effectiveness of osteochondral allografting to repair large (e.g., 10 cm2), full-thickness chondral defect of the knee caused by acute or repetitive trauma have been established. It’s a useful therapeutic option for selected patients.

Osteochondral allografting for all other joints (other than the knee) is experimental. It hasn’t been shown to improve patient outcomes better than conventional treatment.

Osteochondral autografting
The safety and effectiveness of osteochondral autografting, using one or more cores of osteochondral tissue, have been established for the treatment of symptomatic full-thickness cartilage defects of the knee caused by acute or repetitive trauma in patients who have had an inadequate response to a prior surgical procedure, when the inclusionary criteria are met.

Osteochondral autografting for all other joints and any indications other than those listed above is considered experimental.

Treatment of focal articular cartilage lesions with autologous or allogeneic minced cartilage is considered experimental.

Treatment of focal articular cartilage lesions with decellularized osteochondral allograft plugs (e.g., Chondrofix) is considered experimental.

Treatment of focal articular cartilage lesions with reduced osteochondral allograft discs (e.g., ProChondrix, Cartiform) is considered experimental.

Inclusionary and exclusionary criteria have been updated, effective July 1, 2018.

Inclusions:

  • Full-thickness chondral defects of the knee caused by acute or repetitive trauma when other cartilage repair techniques (e.g., microfracture, osteochondral autografting or autologous chondrocyte implantation) would be inadequate due to lesion size, location or depth.
  • Large (area >1.5 cm2) or cystic (volume >3.0 cm3) osteochondral lesions of the talus when autografting would be inadequate due to lesion size, depth or location.
  • Revision surgery after failed prior marrow stimulation for large (area >1.5 cm2) or cystic (volume >3.0 cm3) osteochondral lesions of the talus when autografting would be inadequate due to lesion size, depth or location.

For osteochondral autografting:

  • This procedure is appropriate for patients with full-thickness chondral defect of the knee caused by acute or repetitive trauma in patients who have had an inadequate response to a prior surgical procedure. In addition, all the following criteria must be met:
    • Patient age:
      • Adolescent patients should be skeletally mature, with documented closure of growth plates (e.g., 15 years or older).
      • Adult patients should be too young to be considered an appropriate candidate for total knee arthroplasty or other reconstructive knee surgery (e.g., younger than 55 years)
    • Focal, full-thickness (grade III or IV) unipolar lesions on the weight-bearing surface of the femoral condyles, trochlea, or patella that are between 1 and 2.5 cm2 in size
    • Documented minimal to absent degenerative changes in the surrounding articular cartilage (Outerbridge grade II or less) and normal-appearing hyaline cartilage surrounding the border of the defect
    • Normal knee biomechanics or alignment and stability achieved concurrently with osteochondral grafting
    • Large (area >1.5 cm2) or cystic (volume >3.0 cm3) osteochondral lesions of the talus
    • Revision surgery after failed marrow stimulation for osteochondral lesion of the talus

Exclusions:

  • Osteochondral allografting or autografting for all other joints, including shoulder, elbow and any indications other than those listed above, is considered experimental.
  • Treatment of focal articular cartilage lesions with autologous or allogenic minced cartilage
  • Treatment of focal articular cartilage lesions with decellularized osteochondral allograft plugs (e.g., Chondrofix) is considered experimental.
  • Treatment of focal articular cartilage lesions with reduced osteochondral allograft discs (e.g., ProChondrix, Cartiform) is considered experimental.

78608, 78609, 78811, 78812, 78813, 78814, 78815, 78816, 78999, G0235

Noncovered:

G0219, G0252

Basic benefit and medical policy

Positron emission tomography for oncologic conditions

The safety and effectiveness of PET scanning for selected oncologic applications have been established.  It’s a useful diagnostic option for patients meeting patient selection criteria.

Inclusionary and exclusionary criteria have been updated, effective July 1, 2018.

Inclusions:
General statements
All inclusionary and exclusionary statements apply to both positron emission tomography scans and PET and CT scans, i.e., PET scans with or without PET or CT fusion.

A PET or PET and CT may be appropriate for a patient with a known diagnosis of a malignancy in order to determine the optimal anatomic site for a biopsy or other invasive diagnostic procedure if standard imaging is equivocal. It also may replace conventional imaging when conventional imaging would be inadequate for accurate staging and when clinical management will depend upon the stage of disease. In general, for most solid tumors, a tissue diagnosis is made prior to the performance of PET scanning. PET scans following a tissue diagnosis are performed for staging, not diagnosis. If the results of the PET scan won’t influence treatment decisions, these situations would be considered not medically necessary.

PET scans may be considered appropriate for the following oncologic conditions:

Anal cancer
Inclusions:

  • For the diagnosis, staging, restaging and monitoring of anal cancer

Exclusions:

  • Conditions not listed above

Bone cancer
Inclusions:

  • For the staging of Ewing sarcoma and osteosarcoma

Exclusions:

  • For the staging of chondrosarcoma

Brain cancer
Inclusions:

  • For diagnosis and staging, where lesions metastatic from the brain are identified but no primary is found
  • For restaging, to distinguish recurrent tumor from radiation necrosis

Exclusions:

  • Conditions not listed above

Breast cancer
Inclusions:

  • Staging and restaging of breast cancer
  • Detecting locoregional or distant recurrence or metastasis (except axillary lymph nodes) when suspicion of disease is high and other imaging is inconclusive.
  • Staging axillary lymph nodes

Exclusions:

  • For the differential diagnosis in patients with suspicious breast lesions, or an indeterminate or low suspicion finding on mammography
  • Staging axillary lymph nodes
  • For predicting pathologic response to neoadjuvant therapy for locally advanced disease

Cancers of unknown primary
Inclusions:

  • Patients with an unknown primary who meet all the following criteria:
    • In patients with a single site of disease outside the cervical lymph nodes
    • Patient is considering local or regional treatment for a single site of metastatic disease.
    • Patient has received a negative workup for an occult primary tumor.
    • The PET scan will be used to rule out or detect additional sites of disease that would eliminate the rationale for local or regional treatment.

Exclusions:

  • For patients with an unknown primary including, but not limited to, the following:
    • As part of the initial workup of an unknown primary
    • As part of the workup of patients with multiple sites of disease

Cervical cancer
Inclusions:

  • For the initial staging of patients with locally advanced cervical cancer
  • For the evaluation of known or suspected recurrence

Exclusions:

  • For the initial diagnosis of cervical cancer in all other situations

Colorectal cancer
Inclusions:

  • Staging and restaging (initial and subsequent treatment strategy) to detect and assess resectability of hepatic or extrahepatic metastases of colorectal cancer
  • To evaluate a rising and persistently elevated carcinoembryonic antigen level when standard imaging, including CT scan, is negative

Exclusions:

  • When used as a technique to assess the presence of scarring versus local bowel recurrence in patients with previously resected colorectal cancer
  • When used as a technique contributing to radiotherapy treatment planning

Endometrial cancer
Inclusions include all of the following:

  • Detection of lymph node metastases
  • Assessment of endometrial cancer recurrence

Exclusions:

  • Conditions not listed above

Esophageal cancer
Inclusions:

  • Staging and restaging of esophageal cancer 
  • Determining response to preoperative induction therapy

Exclusions:

  • Detection of primary esophageal cancer

Gastric (stomach) cancer
Inclusions:

  • Diagnosis, staging and restaging of gastric carcinoma if other imaging is inconclusive.
  • Determining response to preoperative induction therapy

Exclusions:

  • Conditions not listed above

Head and neck cancer
Inclusions:

  • For the evaluation of the head and neck in the diagnosis of suspected head and neck cancer
  • For the initial staging of the disease
  • For restaging of residual or recurrent disease during follow up after treatment for their head and neck cancer

Exclusions:

  • Conditions not listed above

Lung cancer
Inclusions:

  • Patients with a solitary pulmonary nodule as a single-scan technique (not dual-time) to distinguish between benign and malignant disease when prior CT scan and chest X-ray findings are inconclusive or discordant
  • To determine resectability for patients with a presumed solitary metastatic lesion from lung cancer
  • As a staging or restaging technique in those with known non-small cell lung cancer

Exclusions:

  • Conditions not listed above

Lymphoma, including Hodgkin’s disease
Inclusions:

  • PET scanning as a technique for staging lymphoma either during initial staging or for restaging at follow-up

Exclusions:

  • Conditions not listed above

Melanoma
Inclusions:

  • Assessing extranodal spread of malignant melanoma at initial staging or at restaging during follow-up treatment

Exclusions:

  • When used as a technique to detect regional lymph node metastases in patients with clinically localized melanoma who are candidates to undergo sentinel node biopsy

Multiple myeloma
Inclusions:

  • For the initial and subsequent treatment strategy of multiple myeloma

Exclusions:

  • Not applicable

Neuroendocrine tumors
Inclusions:

  • For the diagnosis, staging, restaging and monitoring of neuroendocrine tumors

Exclusions:

  • Conditions not listed above

Ovarian cancer
Inclusions:

  • Initial staging of ovarian cancer
  • For the evaluation of patients with signs or symptoms of suspected ovarian cancer recurrence (restaging) when standard imaging, including CT scan, is inconclusive.

Exclusions:

  • For the initial evaluation (not staging) of known or suspected ovarian cancer in all other situations

Pancreatic cancer
Inclusions:

  • For the initial diagnosis and staging of pancreatic cancer when other imaging and biopsy are inconclusive

Exclusions:

  • Evaluating other aspects of pancreatic cancer

Penile cancer
Inclusions:

  • Staging inguinal lymph nodes in patients with squamous cell carcinoma of the penis

Exclusions:

  • All other indications

Prostate cancer
Inclusions:

  • PET scanning with 11C-choline for evaluating response to primary treatment in prostate cancer

Exclusions:

  • PET scanning with 68Gallium in all aspects of managing prostate cancer
  • PET scanning for all other indications

Renal cell carcinoma
Inclusions:

  • Not applicable

Exclusions:

  • PET scanning in all aspects of managing renal cancer

Soft tissue sarcoma
Inclusions:

  • For initial staging prior to resection of an apparently solitary metastasis
  • When the grade of a unresectable tumor remains in doubt after biopsy.
  • Differentiation of suspected tumor from radiation or surgical fibrosis
  • Determination of response to therapy.
  • Gastrointestinal stromal tumor for initial staging and re-staging when there is documented recurrence

Exclusions:

  • When used in evaluation of soft tissue sarcoma including, but not limited to, the following applications:
    • Distinguishing between benign lesions and malignant soft tissue sarcoma
    • Distinguishing between low grade and high grade soft tissue sarcoma
    • Detecting locoregional recurrence
    • Detecting distant metastasis

Testicular cancer
Inclusions:

  • PET scanning in the evaluation of residual mass following chemotherapy of stage IIB and III seminomas

Exclusions:

  • All other indications

Thyroid cancer
Inclusions:

  • For the initial treatment strategy of thyroid cancer types known not to concentrate radioactive iodine
  • For subsequent treatment strategy for differentiated thyroid cancer of follicular cell origin that is known to concentrate radioactive iodine, in all the following situations:
    • When done following prior treatment with thyroidectomy and radioiodine ablation
    • With a current serum thyroglobulin > 10 ng/ml (except in the setting of documented anti-thyroglobulin antibodies)
    • With a negative whole-body RAI scan in the past

Exclusions:

  • For the evaluation of known or suspected differentiated or poorly differentiated thyroid cancer in all other situations

Cancer surveillance
Inclusions:

  • Not applicable

Exclusions:

  • When used as a surveillance tool for patients with cancer or with a history of cancer. A scan is considered surveillance if performed more than six months after completion of cancer therapy (12 months for lymphoma) in patients without objective signs or symptoms suggestive of cancer recurrence

Established
81287

Experimental

81120, 81121

Basic benefit and medical policy

Genetic testing – analysis of MGMT promoter methylation in malignant gliomas

The safety and effectiveness of the analysis of MGMT promoter methylation in malignant gliomas are established. It may be considered a useful option when indicated. Procedure code 81287 will now be an established procedure. This policy is effective May 1, 2018.

The analysis of IDH1/IDH2 mutations for prognostic value is experimental. It hasn’t been scientifically demonstrated to improve patient clinical outcomes.

Inclusionary and exclusionary guidelines

Methylation analysis of the O6-methylguanine DNA methyltransferase (MGMT) gene promoter from glioma tumor tissue is established for individuals who meet all of the following criteria:

  • They have a tumor type consistent with high-grade malignant glioma (e.g., glioblastoma multiforme, anaplastic astrocytoma).
  • Candidate for temozolomide therapy or radiation therapy
  • Methylation results will be used to direct their therapy choices.

MGMT promoter methylation analysis is experimental in situations that don’t meet the above criteria.

Payable
Q4122

Experimental
Q4175

Basic benefit and medical policy

Skin and tissue substitutes

The safety and effectiveness of skin and tissue substitutes approved by the U.S. Food and Drug Administration and the Centers for Medicare & Medicaid Services have been established for patients meeting specified selection criteria. They may be useful therapeutic options when indicated.

Human tissue products are subject to the rules and regulations of banked human tissue by the American Association of Tissue Banks.

  • Alloderm is a human tissue product that is established for use in breast reconstruction and treatment of severe burns.
  • Theraskin is a human tissue product that is established for use in standard therapeutic compression for venous stasis ulcers and standard diabetic foot ulcer care for neuropathic diabetic foot ulcers.
  • GraftJacket is a human tissue product that is established for the treatment of neuropathic diabetic foot ulcers.
  • EpiFix is an amniotic membrane allograft that is established for the treatment of neuropathic diabetic foot ulcers and venous stasis ulcers that have failed to respond to conservative measures.

This policy is effective July 1, 2018.

Inclusions:
The following skin and tissue substitutes are considered established as they have been approved by the FDA.

This list may not be all-inclusive:

  • Apligraft®
  • Biobrane®
  • Cytal® Burn Matrix
  • Cytal® MicroMatrix™
  • Cytal® Wound Sheet
  • Dermagraft®
  • Endoform Dermal Template™
  • Epicel® has FDA Humanitarian Device Approval
  • E-Z Derm™
  • Hyalomatrix®
  • Integra® Bilayer Matrix
  • Integra® Dermal Regeneration Template
  • Integra® Flowable Wound Matrix
  • MediSkin®
  • Oasis® Burn Matrix
  • Oasis® Ultra Tri-Layer Wound Matrix
  • Oasis® Wound Matrix
  • OrCel®
  • Permacol™ (Covidien)
  • PriMatrix™
  • PuraPly Wound Matrix (PuraPly)
  • PuraPly Antimicrobial Wound Matrix (PuraPly AM)
  • Strattice™
  • Suprathel®
  • SurgiMend®
  • Talymed™
  • TenoGlide™
  • TheraSkin®
  • TransCyte®

Exclusions:
All other uses of bioengineered skin and soft tissue substitutes listed above unless they meet the following criteria:

  • FDA approval and provided in accordance with the FDA guidelines
  • Covered by Centers for Medicare & Medicaid Services         

All other skin and soft tissue substitutes including, but not limited to:

  • ACell® UBM Hydrated/Lyophilized Wound Dressing
  • AlloSkin™
  • AlloSkin™ RT
  • Aongen™ Collagen Matrix
  • Architect® ECM, PX, FX
  • ArthroFlex™ (Flex Graft)
  • Atlas Wound Matrix
  • Avagen Wound Dressing
  • AxoGuard® Nerve Protector (AxoGen)
  • CollaCare®
  • CollaCare® Dental
  • Collagen Wound Dressing (Oasis Research)
  • CollaGUARD®
  • CollaMend™
  • CollaWound™
  • Collexa®
  • Collieva®
  • Conexa™
  • Coreleader Colla-Pad
  • CorMatrix®
  • Cymetra™ (Micronized AlloDerm™)
  • Dermadapt™ Wound Dressing
  • DermaPure™
  • DermaSpan™
  • DressSkin
  • Durepair Regeneration Matrix®
  • ENDURAGen™
  • Excellagen
  • ExpressGraft™
  • FlexiGraft®
  • GammaGraft
  • Graftjacket® Xpress, injectable
  • Helicoll™
  • hMatrix®
  • Keramatrix®
  • Kerecis™
  • MariGen™/Kerecis™ Omega3™
  • MatriDerm®
  • Matrix HD™
  • MemoDerm™
  • Microderm® biologic wound matrix
  • NeoForm™
  • NuCel
  • Pelvicol®/PelviSoft®
  • Puros® Dermis
  • RegenePro™
  • Repliform®
  • Repriza™
  • StrataGraft®
  • TenSIX™ Acellular Dermal Matrix
  • TissueMend
  • TheraForm™ Standard/Sheet
  • TruSkin™
  • Veritas® Collagen Matrix
  • XCM Biologic® Tissue Matrix
  • XenMatrix™ AB
EXPERIMENTAL PROCEDURES

0494T, 0495T, 0496T

Basic benefit and medical policy

Ex vivo lung perfusion

Ex vivo lung perfusion is experimental. It hasn’t been scientifically demonstrated to improve patient clinical outcomes.

This policy is effective July 1, 2018.

64640**

**May be used for services other than those indicated in this policy.

Basic benefit and medical policy

Radiofrequency ablation of peripheral nerves to treat pain, including Coolief® Cooled RF

Radiofrequency ablation of peripheral nerves to treat pain, including Coolief® Cooled RF is experimental. It hasn’t been scientifically demonstrated to improve patient clinical outcomes, effective July 1, 2018.

81105, 81106, 81107, 81108, 81109, 81110, 81111, 81112

Basic benefit and medical policy

Genetic testing — Human platelet antigen genotyping

Human platelet antigen genotyping for neonatal alloimmune thrombocytopenia, also known as NAIT, is experimental. It hasn’t been scientifically demonstrated to improve patient clinical outcomes, effective July 1, 2018.

81255, 81406

Basic benefit and medical policy

Genetic testing for Tay-Sachs disease

The safety and effectiveness of genetic testing for Tay-Sachs disease (HEXA gene) is considered established. Genetic testing may be considered a useful diagnostic option when indicated.

This policy is effective July 1, 2018.

For preimplantation testing, refer to the member’s specific certificate for coverage of in-vitro services

Inclusions:
Genetic testing for Tay-Sachs disease (HEXA gene) is established in:

  • Those who belong to high-risk populations (e.g., Ashkenazi Jewish, French-Canadian, Louisiana Cajun, Pennsylvania Dutch or Irish/British Isle heritage)
  • Those unsure of their Ashkenazi Jewish heritage
  • Those with a blood relative with Tay-Sachs disease
  • Partners of those who have been positively identified as a carrier
  • Those with ambiguous β-hexosaminidase A enzyme assay results
  • Those with low β-hexosaminidase A enzyme levels, who aren’t in a high-risk population, where pseudodeficiency is suspected
  • Those who are suspected of having Tay-Sachs disease based on symptoms:
    • For confirmation of diagnosis or
    • For testing to provide information to relatives at risk

Preimplantation or prenatal genetic testing of HEXA gene (for Tay-Sachs disease) is established:

  • When both parents are carriers of HEXA gene variants, or
  • In families with genetically confirmed Tay-Sachs disease

Note: Genetic counseling should be offered prior to testing to explain the significance of anticipated test results.

Exclusions:
Genetic testing when used as screening for Tay-Sachs disease in the general population

81327, 81382, 81479, 82397, 82784, 83520, 84999, 86021, 86140, 86255, 87045, 87046, 87075, 87102, 87177, 87209, 87328, 88346, 88350

Basic benefit and medical policy

Miscellaneous genetic and molecular diagnostic tests

Diagnostic, prognostic and therapeutic genetic testing of :

  1. An affected (symptomatic) individual’s germline to benefit the individual (excluding reproductive testing), or
  2. Of an asymptomatic individual to determine future risk of disease is considered experimental for the following:
    • Ceilac PLUS
    • ColonSentry®
    • Crohn’s Prognostic
    • DecisionDx-Melanoma™
    • DecisionDx-Thymoma
    • DNA Methylation Pathway Profile
    • GI Effects® (Stool)
    • IBD sgi Diagnostic™
    • ImmunoGenomic® Profile
    • Know Error™
    • ResponseDX®: Colon
    • SEPT9 methylated DNA (for example: ColoVantage®, Epi proColon®)
    • TransPredict Fc gamma 3A

This policy is effective July 1, 2018.

81401, 81404, 81405, 81406, 81407, 81408, 81434, 81479

Basic benefit and medical policy

Human genetic testing for retinal dystrophies

Genetic testing in patients with retinal dystrophy for biallelic RPE65 mutation is established in patients who are eligible for voretigene neparvovec-rzyl, also known as SPK-RPE65 gene therapy.

The peer reviewed medical literature hasn’t demonstrated the clinical utility of general genetic testing for retinal dystrophies. Therefore, this service is experimental.

Inclusionary and exclusionary guidelines

Criteria for biallelic RPE65 mutation testing:

  • Visual acuity of 20/60 or worse in both eyes, or
  • Binocular visual field less than 20 degrees in any meridian, and
  • Retinal thickness of >100 microns within the posterior pole
All requests must be supported by submission of chart notes and patient specific documentation.

Established
A0430, A0431, A0435, A0436

Non-established

A0420, S9960, S9961

Basic benefit and medical policy

Air ambulance services

The safety and effectiveness of air ambulance services have been established. In order for medical necessity to be established, the attending/ordering physician must determine that the patient’s condition requires air ambulance transport and that any alternative form of transport (ground ambulance, commercial transport) would be clinically inappropriate or detrimental to the health or outcome of the patient.

Transport by fixed wing or rotary wing transport may also be required when the patient requiring transport is physically inaccessible by ground ambulance.

This policy is effective July 1, 2018.

Inclusions (must meet all):

  • Clinical condition must support medical necessity and need for air transport
  • Transport by commercial or ground ambulance is clinically inappropriate — usually due to clinical instability of the patient
  • Ground ambulance transport may be appropriate but patient is physically inaccessible
  • Transport is directed to the nearest facility capable of providing necessary care or to a capable facility within a 25-mile radius of the nearest facility.**

**Transport beyond the 25-mile radius of the nearest capable facility may be reviewed based on the patient’s case or care management needs and other factors as determined by the attending physician in collaboration with Blue Cross Blue Shield of Michigan and Blue Care Network.

Exclusions:

  • Patients with contracts or certificates specifically excluding coverage for air ambulance
  • Patients who are pronounced dead before the ambulance is called
  • Transport where patient’s clinical condition doesn’t require air ambulance transport
  • Transport by an entity that isn’t licensed to provide air ambulance services (e.g., commercial airlines)
  • Transport provided by fire departments, rescue squads or other emergency transport providers whose fees are in the form of donations

(Services involving a destination other than an acute care facility such as a specialized nursing facility, rehabilitation facility or home are rarely considered to meet coverage criteria and should be preceded by a prior authorization communication with Blue Cross Blue Shield of Michigan/Blue Care Network.)

GROUP BENEFIT CHANGES

American Axle

American Axle acquired the following groups:

  • Metaldyne Performance Group LLC (group number 71473)
  • Hephaestus Holdings Inc. (group number 71343)
  • Grede Holdings LLC (group number 71743)
  • Cloyes Gear & Products Inc. (group number 71747)

Effective July 1, 2018, these groups will be canceled and the membership contracts will be transferred into American Axle — group number 75415.

New plans that will be created under American Axle, effective July 1, 2018, are as follows:

  • Consumer Basic HSA Blue Cross Blue Shield of Michigan plan
  • Consumer Basic HSA Aetna plan
  • Consumer Plus HSA Aetna plan
  • OMF PPO Legacy plan
  • U.S. Salaried Inpatriates PPO plan

Group number: 75415
Alpha prefix: PPO (AXL)
Platform: NASCO

Plans offered:
Medical/surgical
Hearing
Prescription drugs: ESI Direct (carve-out) for all plans with an exception: AAM Brillion Retiree CMM-PPO


Pharmacy

Six additional drugs to be added to commercial PPO 15-day Specialty Drug Limitation Program, starting Aug. 1

Starting Aug. 1, 2018, the following six drugs are being added to the Blue Cross Blue Shield of Michigan commercial PPO 15-Day Specialty Drug Limitation Program:

  • Bosulif®
  • Caprelsa®
  • Exjade®
  • Erivedge®
  • Gilotrif®
  • Jadenu®

Instead of a 30-day supply, we’ll limit all fills to a 15-day supply. This includes first fills and refills. Members will pay half of their copayment for a 15-day supply.

Blue Cross limits the day-supply quantity of a medication that a pharmacy can dispense to:

  • Help save members money on copayments
  • Reduce drug waste

We’ll add more drugs to the 15-day program throughout the year. Here’s the full list, including the six new drugs:

Blue Cross commercial PPO
15-day Specialty Drug Limitation Program
Full drug list as of Aug. 1, 2018

Afinitor®

Bosulif®

Afinitor® Disperz

Cabometyx®

Calquence®

Caprelsa®

Cometriq®

Erivedge®

Exjade®

Gilotrif®

Imbruvicia® capsules

Lenvima®

Nexavar®

Nerlynx®

Tarceva®

Verzenio™

Votrient™

Zejula™

Zelboraf®

Zytiga™


Authorization for Fasenra™ and Luxturna™ required for Medicare Advantage members starting in August

As communicated in a May web-DENIS message, for dates of service on or after Aug. 7, 2018, authorization will be required for the following Part B specialty drugs covered under the medical benefit for Medicare Plus BlueSM PPO and BCN AdvantageSM members:

  • Fasenra (benralizumab)
  • Luxturna (voretigene neparvovec-rzyl)

Authorization for these drugs is already required for Blue Cross Blue Shield of Michigan and Blue Care Network commercial members.

For Medicare Plus Blue and BCN Advantage members, these medications require authorization when they are billed on a professional HCFA 1500 claim form or by electronic submission via ANSI 837P for these sites of care:

  • Physician office (place of service 11)
  • Outpatient facility (place of service 19, 22 and 24 for Medicare Plus Blue members and place of service 19 and 22 BCN Advantage members)

Authorization isn’t required for these medications when they are billed on a facility claim form, such as the UB-92, UB-04 or UCB.

You should bill both medications with procedure code J3590 and submit authorization requests for these medications through the NovoLogix online tool. Authorization must be obtained prior to administering the medications.


Commercial Medical Drug Prior Authorization Program adds Ilumya™

Starting Aug. 1, 2018, Ilumya (tildrakizumab-asmn) will be part of the Blue Cross Blue Shield of Michigan commercial Medical Drug Prior Authorization Program.

You can find information about the program by logging in to web-DENIS, clicking on BCBSM Provider Publications and Resources, and selecting Newsletters and Resources. Click Forms (under Other Resources), then Physician administered medications.

Keep in mind that the prior authorization requirement doesn’t apply to Federal Employee Program® members.

The list below reflects all the medications in the program as of Aug. 1:

Drug names

Actemra®

Elaprase®

Kalbitor®

Remicade®

Acthar® gel

Elelyso™           

Kanuma™

Ruconest®

Adagen®               

Entyvio™

Krystexxa®

Signifor® LAR

Aldurazyme®       

Exondys 51™

Lemtrada™

Simponi Aria®

Aralast NP™

Fabrazyme®

Lumizyme®

Soliris®

Aveed®

Fasenra™

Luxturna™

Spinraza™

Benlysta®

Firazyr®

Makena®

Stelara®

Berinert®

Flebogamma® DIF

Mepsevii™

Stelara IV®

Bivigam™

Gammagard Liquid®

Myobloc®

Synagis®

Botox®

Gammagard® S/D

Myozyme®          

Testopel®

Brineura™

Gammaked®

Naglazyme®    

Tysabri®

Carimune® NF

Gammaplex®

Nplate®

Vimizim™

Cerezyme®

Gamunex®

Nucala®

Vpriv®

Cimzia®

Glassia™

Ocrevus™

Xeomin®

Cinqair®

Hizentra®

Octagam®

Xgeva®

Cinryze®

HyQvia®

Orencia®

Xiaflex®

Cosentyx™

Ilaris®

Privigen®

Xolair®

Crysvita®

Ilumya™

Prolastin®-C

Yescarta®

Cuvitru®

Immune globulin

Prolia®

Zemaira®

Dysport®

Inflectra™

Radicava™

Zinplava™


DME

Clarification: Requirements for providers billing DME prosthetics, orthotics and supplies

All durable medical equipment and medical supply providers that bill for custom prosthetic and orthotic services (including professional providers that meet Centers for Medicare & Medicaid Services exemption requirements) will be required to bill Blue Cross Blue Shield of Michigan claims with a separate, valid prosthetic and orthotic supplier provider PIN.

Although CMS allows for payment using only one provider DMEPOS NPI, effective July 1, 2018, Blue Cross will require a separate P&O provider NPI for billing custom P&O and a DME provider NPI for billing DME and off-the-shelf P&O services. All claims must include your NPI and the taxonomy code affiliated with your DMEPOS supplier number.

If you have a 10-digit DMEPOS supplier number, also known as a DMEPOS provider transaction access number, from the National Supplier Clearinghouse, and you bill for custom P&O HCPCS codes, submit a copy to Blue Cross’ Provider Enrollment and Data Management to request registration as a P&O provider. If you aren’t a registered P&O provider, your claims for custom P&O services will be rejected as not payable to your provider specialty and you’ll be liable for any costs.

Contact Provider Enrollment and Data Management at 1-800-822-2761 for more information to update your provider enrollment status.

Blue Cross Off-the-Shelf L Codes
Payable to a DME Provider

L0120

L0621

L0650

L1848

L3675

L3925

L0160

L0623

L0651

L1850

L3710

L3927

L0172

L0625

L0980

L1902

L3762

L3930

L0174

L0628

L0982

L1906

L3809

L4350

L0450

L0641

L0984

L3100

L3908

L4361

L0455

L0642

L1812

L3170

L3912

L4370

L0457

L0643

L1830

L3650

L3916

L4387

L0467

L0648

L1833

L3660

L3918

L4397

L0469

L0649

L1836

L3670

L3924

L4398


Additional codes added to capped rental list

Effective Sept. 1, 2018, Blue Cross Blue Shield of Michigan is removing more than 50 HCPCS codes from the purchase-only list and adding them to the capped rental list. Click here to see the updated list of capped rental HCPCS codes, with the newly added codes bolded. To see the list of purchase-only codes, click here.

No portion of this publication may be copied without the express written permission of Blue Cross Blue Shield of Michigan, except that BCBSM participating health care providers may make copies for their personal use. In no event may any portion of this publication be copied or reprinted and used for commercial purposes by any party other than BCBSM.

*CPT codes, descriptions and two-digit numeric modifiers only are copyright 2017 American Medical Association. All rights reserved.